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Fig. 4 | Cancer Cell International

Fig. 4

From: LINC01806 mediated by STAT1 promotes cell proliferation, migration, invasion, and stemness in non-small cell lung cancer through Notch signaling by miR-4428/NOTCH2 axis

Fig. 4

STAT1 activates the transcription of LINC01806. A Venn diagram depicted five TFs selected by GEPIA database and HumanTFDB. B RT-qPCR was performed to examine STAT1 and LINC01806 expression in NSCLC cells upon STAT1 knockout. C DNA motif of STAT1 along with one predicted binding site of STAT1 in LINC01806 promoter was predicted from JASPAR. D ChIP assay was utilized to test the binding affinity of STAT1 and LINC01806 promoter. E The combination of STAT1 and LINC01806 promoter was detected through luciferase reporter assay. **P < 0.01, n.s. no significance

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Cancer Cell International

ISSN: 1475-2867

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