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Fig. 4 | Cancer Cell International

Fig. 4

From: Long non-coding RNA LSAMP-1 is down-regulated in non-small cell lung cancer and predicts a poor prognosis

Fig. 4

Overexpression of Lnc-LSAMP-1 inhibited NSCLC tumorigenesis and metastasis in vivo. a Nude mice inoculated subcutaneously with A549 and PC-9 cells. Tumor growth rate and tumor volume are compared between Lnc-LSAMP-1 overexpression group and control group. b A subcutaneous tumor-forming HE section of nude mice in xenograft. c The lung suspected metastases in nude mice with A549 and PC-9 cells injected via tail vein. The black circle indicated the suspected cancerous lesions in the naked eyes of sacrificed nude mice. d A HE slice of suspicious lung nodules in nude mice injected with tail vein injection. Scale bar: 100 μm. Significance was defined as p < 0.05 (*p < 0.05; **p < 0.01; ***p < 0.001)

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