Characteristic | Southern samples N (%) | Eastern samples N (%) | Total N (%) | ||||||
---|---|---|---|---|---|---|---|---|---|
Low expression | High expression | P value | Low expression | High expression | P value | Low expression | High expression | P value | |
Age | |||||||||
  < 60 | 40 (69.0) | 18 (31.0) | 0.155 | 19 (63.3) | 11 (36.7) | 0.311 | 59 (67.0) | 29 (33.0) | 0.508 |
   ≥ 60 | 32 (56.1) | 25 (43.9) |  | 19 (76.0) | 6 (24.0) |  | 51 (62.2) | 31 (37.8) |  |
Gender | |||||||||
 Female | 21 (67.7) | 10 (32.3) | 0.489 | 10 (62.5) | 6 (37.5) | 0.722 | 31 (66.0) | 16 (34.0) | 0.833 |
 Male | 51 (60.7) | 33 (39.3) |  | 28 (71.8) | 11 (28.2) |  | 79 (64.2) | 44 (35.8) |  |
Family tumor history | |||||||||
 No | 62 (60.8) | 40 (39.2) | 0.407 | 36 (70.6) | 15 (29.4) | 0.767 | 98 (64.1) | 55 (35.9) | 0.593 |
 Yes | 10 (76.9) | 3 (23.1) |  | 2 (50.0) | 2 (50.0) |  | 12 (70.6) | 5 (29.4) |  |
Smoking | |||||||||
 No | 25 (64.1) | 14 (35.9) | 0.813 | 11 (73.3) | 4 (26.7) | 0.929 | 36 (66.7) | 18 (33.3) | 0.715 |
 Yes | 47 (61.8) | 29 (38.2) |  | 27 (67.5) | 13 (32.5) |  | 74 (63.8) | 42 (36.2) |  |
Stage (TNM) | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 I + II | 35 (74.5) | 12 (25.5) | 0.029 | 16 (84.2) | 3 (15.8) | 0.078 | 51 (77.3) | 15 (22.7) | 0.006 |
 III + IV | 37 (54.4) | 31 (45.6) |  | 22 (61.1) | 14 (38.9) |  | 59 (56.7) | 45 (43.3) |  |
T status | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 1 + 2 | 47 (66.2) | 24 (33.8) | 0.312 | 13 (54.2) | 11 (45.8) | 0.035 | 60 (63.2) | 35 (36.8) | 0.635 |
 3 + 4 | 25 (56.8) | 19 (43.2) |  | 25 (80.6) | 6 (19.4) |  | 50 (66.7) | 25 (33.3) |  |
N status | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 0 | 34 (75.6) | 11 (24.4) | 0.021 | 22 (75.9) | 7 (24.1) | 0.251 | 56 (75.7) | 18 (24.3) | 0.009 |
 1 + 2 + 3 | 38 (54.3) | 32 (45.7) |  | 16 (61.5) | 10 (38.5) |  | 54 (56.3) | 42 (43.8) |  |
M status | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 0 | 54 (65.1) | 29 (34.9) | 0.382 | 23 (62.2) | 14 (37.8) | 0.111 | 77 (64.2) | 43 (35.8) | 0.820 |
 1 | 18 (56.3) | 14 (43.7) |  | 15 (83.3) | 3 (16.7) |  | 33 (66.0) | 17 (34.0) |  |
Histological classification | Â | Â | Â | Â | Â | Â | Â | Â | Â |
 Adenocarcinoma | 39 (65.0) | 21 (35.0) | 0.632 | 15 (68.2) | 7 (31.8) | 1.000 | 54 (65.9) | 28 (34.1) | 0.752 |
 Squamous carcinoma | 16 (55.2) | 13 (44.8) |  | 13 (68.4) | 6 (31.6) |  | 29 (60.4) | 19 (39.6) |  |
 Other typesa | 17 (65.4) | 9 (34.6) |  | 10 (71.4) | 4 (28.6) |  | 27 (67.5) | 13 (32.5) |  |