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Fig. 6 | Cancer Cell International

Fig. 6

From: KMT2B promotes the growth of renal cell carcinoma via upregulation of SNHG12 expression and promotion of CEP55 transcription

Fig. 6

The effect of SNHG12/E2F1/CEP55 on RCC growth and angiogenesis in vivo. Nude mice were treated with sh-SNHG12 + oe-NC, sh-SNHG12 + oe-E2F1, sh-E2F1 + oe-NC or sh-E2F1 + oe-CEP55. A Tumor volume of mice. B Representative images showing xenografts in mice. C Tumor weight of mice. D The mRNA expression of E2F1 and CEP55 in tumor tissues of mice was detected by RT-qPCR. E The protein expression of VEGF in tumor tissues of mice was detected by immunohistochemistry. F Detection of the protein expression of MMP-2, MMP-9 and VEGF in tumor tissues of mice by Western blot; *p < 0.05, **p < 0.01. n = 6

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Cancer Cell International

ISSN: 1475-2867

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