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Table 2 Function of DANCR in animal models

From: A review on the role of DANCR in the carcinogenesis

Tumor type Results References
Bladder cancer ∆ DANCR: ↓ tumor volume, tumor growth and metastasis [8]
∆ DANCR: ↓ tumor weight, and tumor growth [9]
Breast cancer ∆ DANCR: ↓ tumor growth [27]
∆ DANCR: ↓ tumor growth [29]
∆ DANCR: ↓ tumor growth [35]
∆ DANCR: ↓ tumor weight, tumor volume [36]
∆ DANCR: ↓ tumor growth [37]
RGD-PEG-ECO/siDANCR nanoparticles: ↓ proliferation [38]
Cervical cancer ∆ DANCR: ↓ tumor growth [40]
∆ DANCR: ↓ tumor weight, tumor volume, and tumor growth [41]
↑ miR-665 (a target of DANCR): ↓ tumor weight and tumor growth [42]
Cholangiocarcinoma ∆ DANCR: ↓ tumor growth [43]
∆ DANCR: ↓ tumor weight and tumor growth [44]
Colon cancer ∆ DANCR: ↓ glycolysis rate and ↑ cisplatin sensitivity [21]
∆ DANCR: ↓ tumor formation and metastasis [22]
∆ DANCR: ↓ tumor volume, and tumor growth [45]
Colorectal cancer ↑↑ DANCR: ↑ tumor volume and tumor growth [49]
Gastric cancer ∆ DANCR: ↓ tumor growth [31]
∆ DANCR: ↓ tumor weight, tumor volume, tumor size and proliferation [32]
↑↑ DANCR: ↑ cell growth and tumorigenicity [54]
Glioma ∆ DANCR: ↓ tumor weight, tumor volume, and tumor growth [55]
∆ DANCR: ↑ apoptosis-inducing roles of cisplatin in vivo [58]
Hepatocellular carcinoma ↑↑ DANCR: ↑ sorafenib resistance [18]
∆ DANCR: ↓ cell vitality, tumor shrinkage [19]
∆ DANCR: ↓ tumor growth and lung metastasis [20]
∆ DANCR: ↓ tumor growth and lung metastasis [62]
Lung cancer ∆ DANCR: ↓ tumor growth [10]
∆ DANCR: ↓ tumor growth [12]
∆ DANCR: ↓ tumor weight, tumor volume and tumor growth [65]
∆ DANCR: ↓ tumor growth [66]
∆ DANCR: ↓ tumor volume [67]
Nasopharyngeal carcinoma ∆ DANCR: ↓ tumor size and tumor growth [71]
∆ DANCR: ↓ tumor volume and tumor weight [72]
∆ DANCR: ↓ invasion and metastasis [73]
Oral squamous cell carcinoma ∆ DANCR: ↓ tumor weight, tumor volume, and tumor growth [75]
Osteosarcoma ↑↑ DANCR: ↑ tumor growth and metastasis [3]
∆ DANCR: ↓ tumor size and tumor volumes [2]
∆ DANCR: ↓ tumor growth and autophagy [5]
∆ METTL3: ↓ tumor volumes (DANCR could be a target of METTL3) [6]
Ovarian cancer ∆ DANCR: ↓ tumor weight, tumor volume, and tumor growth [78]
Pancreatic cancer DANCR was up-regulated as pancreatic cancer progressed [89]
∆ DANCR: ↓ tumor growth [25]
Prostate cancer ∆ DANCR: ↓ tumor weight, tumor volume, and tumor growth [84]
∆ DANCR: ↓ metastasis [85]
Tongue squamous cell carcinoma ∆ DANCR: ↓ tumor growth and tumor formation [88]
  1. ∆: knock-down or deletion, NOD-SCID-gamma: severe combined immunodeficient, GBM: glioblastoma