A review on the role of DANCR in the carcinogenesis

Ghafouri-Fard, Soudeh; Khoshbakht, Tayyebeh; Hussen, Bashdar Mahmud; Baniahmad, Aria; Taheri, Mohammad; Samadian, Mohammad

doi:10.1186/s12935-022-02612-z

Table 2 Function of DANCR in animal models

From: A review on the role of DANCR in the carcinogenesis

Tumor type	Results	References
Bladder cancer	∆ DANCR: ↓ tumor volume, tumor growth and metastasis	[8]
Bladder cancer	∆ DANCR: ↓ tumor weight, and tumor growth	[9]
Breast cancer	∆ DANCR: ↓ tumor growth	[27]
	∆ DANCR: ↓ tumor growth	[29]
	∆ DANCR: ↓ tumor growth	[35]
	∆ DANCR: ↓ tumor weight, tumor volume	[36]
	∆ DANCR: ↓ tumor growth	[37]
	RGD-PEG-ECO/siDANCR nanoparticles: ↓ proliferation	[38]
Cervical cancer	∆ DANCR: ↓ tumor growth	[40]
	∆ DANCR: ↓ tumor weight, tumor volume, and tumor growth	[41]
	↑ miR-665 (a target of DANCR): ↓ tumor weight and tumor growth	[42]
Cholangiocarcinoma	∆ DANCR: ↓ tumor growth	[43]
Cholangiocarcinoma	∆ DANCR: ↓ tumor weight and tumor growth	[44]
Colon cancer	∆ DANCR: ↓ glycolysis rate and ↑ cisplatin sensitivity	[21]
	∆ DANCR: ↓ tumor formation and metastasis	[22]
	∆ DANCR: ↓ tumor volume, and tumor growth	[45]
Colorectal cancer	↑↑ DANCR: ↑ tumor volume and tumor growth	[49]
Gastric cancer	∆ DANCR: ↓ tumor growth	[31]
	∆ DANCR: ↓ tumor weight, tumor volume, tumor size and proliferation	[32]
	↑↑ DANCR: ↑ cell growth and tumorigenicity	[54]
Glioma	∆ DANCR: ↓ tumor weight, tumor volume, and tumor growth	[55]
Glioma	∆ DANCR: ↑ apoptosis-inducing roles of cisplatin in vivo	[58]
Hepatocellular carcinoma	↑↑ DANCR: ↑ sorafenib resistance	[18]
	∆ DANCR: ↓ cell vitality, tumor shrinkage	[19]
	∆ DANCR: ↓ tumor growth and lung metastasis	[20]
	∆ DANCR: ↓ tumor growth and lung metastasis	[62]
Lung cancer	∆ DANCR: ↓ tumor growth	[10]
	∆ DANCR: ↓ tumor growth	[12]
	∆ DANCR: ↓ tumor weight, tumor volume and tumor growth	[65]
	∆ DANCR: ↓ tumor growth	[66]
	∆ DANCR: ↓ tumor volume	[67]
Nasopharyngeal carcinoma	∆ DANCR: ↓ tumor size and tumor growth	[71]
	∆ DANCR: ↓ tumor volume and tumor weight	[72]
	∆ DANCR: ↓ invasion and metastasis	[73]
Oral squamous cell carcinoma	∆ DANCR: ↓ tumor weight, tumor volume, and tumor growth	[75]
Osteosarcoma	↑↑ DANCR: ↑ tumor growth and metastasis	[3]
	∆ DANCR: ↓ tumor size and tumor volumes	[2]
	∆ DANCR: ↓ tumor growth and autophagy	[5]
	∆ METTL3: ↓ tumor volumes (DANCR could be a target of METTL3)	[6]
Ovarian cancer	∆ DANCR: ↓ tumor weight, tumor volume, and tumor growth	[78]
Pancreatic cancer	DANCR was up-regulated as pancreatic cancer progressed	[89]
Pancreatic cancer	∆ DANCR: ↓ tumor growth	[25]
Prostate cancer	∆ DANCR: ↓ tumor weight, tumor volume, and tumor growth	[84]
Prostate cancer	∆ DANCR: ↓ metastasis	[85]
Tongue squamous cell carcinoma	∆ DANCR: ↓ tumor growth and tumor formation	[88]

∆: knock-down or deletion, NOD-SCID-gamma: severe combined immunodeficient, GBM: glioblastoma

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