Fig. 1
From: Radiotherapy-activated NBTXR3 nanoparticles modulate cancer cell immunogenicity and TCR repertoire
NBTXR3 Improves calreticulin exposure. Flow-cytometry analyses of the Ecto-CALR signal acquired 24 h post-treatment by RT, for (A) HCT116, (B) 42-MG-BA and (C) CT26.WT cells. HCT116, 42-MG-BA and CT26.WT cells were treated overnight respectively with 800µM, 100 µM or 400µM of NBTXR3, then irradiated. The next day, cells were stained for Ecto-CALR and fluorescence was determined by flow-cytometry. Presented data were obtained from at least three independent experiments (n ≥ 3). Data are represented as mean fold increase ± SEM compared to unirradiated control cells. D Detailed fold-increase