From: Recent knowledge of NFATc4 in oncogenesis and cancer prognosis
Enzyme | PTM | Studied sites | Verification | References |
---|---|---|---|---|
Calcineurin | Dephosphorylation | multisites | 3 | [2] |
p38 MAP kinase | Phosphorylation | Ser168, 170 | 3, 4 | |
mTOR | Phosphorylation | Ser168, 170 | 2, 3 | [35] |
MAPK7 (ERK5) | Phosphorylation | Ser168, 170 | 2, 3 | [35] |
IRAK-1 | Phosphorylation | Ser168, 170 | 3 | [40] |
JNK1/2 | Phosphorylation | Ser213, 217 | 2, 3, 4 | [41] |
CDK3 | Phosphorylation | Ser259 | 2, 3, 4 | [19] |
PKA | Phosphorylation | Ser272, 289 | 2, 3, 4 | [42] |
RSK2 | Phosphorylation | Ser289, 344, 676 | 1, 2, 3, 4 | |
PARP-1 | ADP-ribosylation | Glu418 | 1, 2, 3, 4 | [36] |
- | Ubiquitination | - | 3 | [37] |
SIRT6 | Deacetylation | - | 3 | [38] |