Fig. 6
From: Mechanisms of miR-3189-3p-mediated inhibition of c-MYC translation in triple negative breast cancer
MiR-3189-3p directly targets 4EBP1 3′UTR. A Alignment of 4EBP1 3′UTR sequence with miR-3189-3p. In bold are indicated the mutated bases. B Luciferase assay of MDA-MB-231 cells co-transfected with miR-3189-3p (miR) or control (Ctrl) and either 4EBP1 3′UTR (WT 3′UTR) or the mutated 4EBP1 3′UTR (Mut 3′UTR). The scramble sequence of the miRNA was used as control. * Indicates statistical significance