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Fig. 3 | Cancer Cell International

Fig. 3

From: Identification of icaritin derivative IC2 as an SCD-1 inhibitor with anti-breast cancer properties through induction of cell apoptosis

Fig. 3

The antiproliferation effect of ICT derivatives in breast cancer cell lines. IC2 inhibited the growth of MCF-7 (A) and SK-BR-3 (B) cells to a greater extent than ICT and the other derivatives. C IC2 treatment (from 5 μM to 20 μM) for 24 h showed no cytotoxicity to normal human embryonic kidney cells (293T). D Observation under the microscope at ×50  magnification. Data are presented as the mean ± SEM of three independent experiments (n = 3). E LIVE/DEAD assay showed that the number of dead cells increased significantly after treatment with 20 μM IC2. *P < 0.05, **P < 0.01 and ***P < 0.001 vs. control

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Cancer Cell International

ISSN: 1475-2867

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