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Fig. 4 | Cancer Cell International

Fig. 4

From: Identification of icaritin derivative IC2 as an SCD-1 inhibitor with anti-breast cancer properties through induction of cell apoptosis

Fig. 4

IC2 inhibits the expression and activity of SCD1 dose-dependently in MCF-7 cells. MCF-7 cells were treated with three concentrations of IC2 for 24 h, the protein (A and B), mRNA (C) and activity (D and E) levels of SCD1 were detected. (B) Quantification of the protein expression levels of SCD1. E Quantification of SCD1 activity levels. Data are presented as the mean ± SEM of three independent experiments (n = 3). *P < 0.05, **P < 0.01 and ***P < 0.001 vs. control

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