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Fig. 4 | Cancer Cell International

Fig. 4

From: Comparison of anti-cancer effects of novel protein disulphide isomerase (PDI) inhibitors in breast cancer cells characterized by high and low PDIA17 expression

Fig. 4

Effects of parallel PDIA17 and PDIA1 inhibition (C-3353) on breast cancer cell proliferation, migration and adhesion in PDIA17 low and high expressing cell line (MDA-MB-231 vs MCF-7, respectively). A Half-maximal inhibitory concentration (IC50) for PDIA17 and PDIA1 inhibitor in viability test in breast cancer cell lines; B Effects of parallel PDIA17 and PDIA1 inhibition on adhesion of breast cancer cell lines to collagen, type I; C Effects of parallel PDIA17 and PDIA1 inhibition on wound-healing and migration of breast cancer cells

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