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Table 2 Diagnostic value of MIR4435-2HG in cancers and non-cancerous conditions [ALL: Acute lymphoblastic leukemia, AUC: Area under the Curve]

From: Long non-coding RNA MIR4435-2HG: a key molecule in progression of cancer and non-cancerous disorders

Disease

Expression

Number of samples

Sensitivity

Specificity

AUC

Sample

References

Gastric cancer

Up

51 cancer patients and 53 healthy controls

90.2

74.5

88.2

Plasma

[26]

Gastric cancer

Up

72 cancer patients and adjacent non-cancerous tissues

80

70

83.1

Serum

[27]

Hepatocellular cancer

Up

58 cancer patients and 45 healthy controls

75.9

95.9

91

Serum

[36]

Colorectal cancer

Up

70 cancer patients and adjacent non-cancerous tissues

72

80

81

Tissue

[21]

Colon cancer

Up

46 cancer patients and 42 healthy controls

–

–

84.8

Serum

[20]

Ovarian carcinoma

Up

66 cancer patients and 54 healthy controls

–

–

88.2

Plasma

[50]

ALL

Up

32 cancer patients and 32 healthy controls

–

–

89.5

Bone marrow

[64]

Renal cell carcinoma

Up

118 cancer patients and adjacent non-cancerous tissues

–

–

94.6

Tissue

[67]

Osteoarthritis

Down

78 osteoarthritis and 58 healthy controls

–

–

96

joint fluid

[14]

Osteoporosis

Down

88 osteoporosis patients and 57 healthy control

–

–

92

plasma

[15]

Non-traumatic ONFH

Down

36 ONFH patients and 30 healthy controls

–

–

81.8

Serum

[13]