Fig. 1

The mRNA expression levels of GRB10 in the TCGA, CGGA and GEO dataset. a-c The expression of GRB10 in different histological grades was analyzed based on the gene expression profile data, including CGGA (a) (grade II, n = 172; grade III, n = 248; and grade IV, n = 237), TCGA (b) (grade II, n = 311; grade III, n = 208; and grade IV, n = 166), GEO (c) (grade II, n = 5; grade III, n = 13; and grade IV, n = 32). d qRT-PCR was used to evaluate the expression of GRB10 in tumor tissues (peritumor tissue, n = 13; grade II, n = 20; grade III, n = 16; and grade IV, n = 32). Data are analyzed by Mann–Whitney test. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001