Fig. 4
From: GRB10 is a novel oncogene associated with cell proliferation and prognosis in glioma
Knockdown of GRB10 inhibits cell invasion and migration in glioma. a The transwell migration assay showed that knockdown of GRB10 inhibited migration and invasion of U251. b Image J was used to count the cells that had invaded or migrated into the bottom of the transwell inserts. c Knockdown of GRB10 was shown to inhibit the migration and invasion of SHG44 cells. d Image J was used to count the SHG44 cells that had invaded or migrated into the bottom of the transwell inserts. e–f Wound healing assay showed that knockdown of GRB10 was inhibit the ability of migration in SHG44 cells. Data are analyzed by a two-tailed Student’s t-test. *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001