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Table 1 An overview of the effect of the six toxicologically relevant metals in EMT

From: Toxic metals in the regulation of epithelial–mesenchymal plasticity: demons or angels?

Element

Form

Promotes EMT

Inhibits EMT

Arsenic

AsO2-

Yes

ND

 

ATO

Yes

Yes

Cadmium

Cd2+

Yes

Yes

Cobalt

Co2+

Yes

ND

Chromium

Cr6+

Yes

ND

Nickel

Ni2+

Yes

ND

Copper

Cu2+

Yes

Yes

  1. Yes reported in the literature, ND no data (no relevant data was available at the time of this publication)
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Cancer Cell International

ISSN: 1475-2867

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