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Fig. 3 | Cancer Cell International

Fig. 3

From: A pan-cancer analysis of thioredoxin-interacting protein as an immunological and prognostic biomarker

Fig. 3

Mutation and modification feature of TXNIP in different TCGA tumors. A The genetic alteration type and frequency of TXNIP in various cancers. B The three-dimensional structure of TXNIP protein. C Mutation site of the TXNIP. D Correlation analysis of tumor mutational burden (TMB) with TXNIP gene expression. E Correlation analysis of microsatellite instability (MSI) with TXNIP gene expression. F Correlation analysis of four DNA methyltransferases (DNMT1, DNMT2, DNMT3A, DNMT3B) with TXNIP gene expression. G Correlation analysis of five MMR genes (EPCAM, MLH1, MSH2, MSH6 and PMS2) with TXNIP gene expression. H The predicted ubiquitination and phosphorylation sites of TXNIP protein

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