Fig. 7

AhR expression positively correlates with the levels of VEGF-B. A AhR and VEGF-B mRNA expression levels in trophoblast cell lines. (a) Choriocarcinoma JEG-3 cells vs. extravillous trophoblast HTR-8 cells in GSE20510; (b) choriocarcinoma JEG-3 cells vs. BoWo cells in GSE2531; B AhR and VEGF-B mRNA expression levels in AhR agonist treated cells vs. parent cells. (a) For mesenchymal stem cells, BMH cells, in GSE95072. (b) For breast cancer MCF-7 cells in GSE98514; (c) for lung cancer A549 cells in GSE122733. C AhR and VEGF-B mRNA expression levels in AhR antagonist or AHR knockdown cells vs. parent cells. (a) For primary human acute myeloid leukemia cells in GSE48843; (b) for breast cancer MCF-7 cells in GSE52036; (c) for multiple myeloma MM1S cells in GSE117160. D Molecular functional network map of AhR and VEGF-B was analyzed using the GeneMANIA tool. AhR aryl hydrocarbon receptor