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Fig. 3 | Cancer Cell International

Fig. 3

From: Identification of genes with high heterogeneity of expression as a predictor of different prognosis and therapeutic responses in colorectal cancer: a challenge and a strategy

Fig. 3

Association of CXCL1, SFTA2, SELE and SACS expression with prognosis of CRC patients. A Differential expression for identified genes in MIS compared to MSS based on TCGA data. B Volcano plot for univariate Cox regression results for genes with HHE and HR > 1 and logRank < 0.01 were considered for selection of genes related to patients survival. C Calculate patients' risk score for four genes CXCL1, SFTA2, SELE, and SACS using their expression level and beta coefficient of multivariate Cox regression test. The calculated median score was used to divide patients into high-risk and low-risk groups. D Kaplan Meier is shown for high risk patients versus low risk patients. E Sensitivity and specificity of expression level of CXCL1, SFTA2, SELE, and SACS from high risk group against low risk

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Cancer Cell International

ISSN: 1475-2867

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