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Fig. 2 | Cancer Cell International

Fig. 2

From: METTL3 suppresses anlotinib sensitivity by regulating m6A modification of FGFR3 in oral squamous cell carcinoma

Fig. 2

FGFR3 expression level affects antitumor activity of anlotinib in OSCC. A FGFR3 silenced effects were examined by western blotting. B Cell proliferation inhibition assay showed that the cytotoxic ability of anlotinib in OSCC cells (24 h) after transfected with siFGFR3 or treated with rhFGF. C Cell apoptosis assay showed the ratio of apoptosis cells of anlotinib-treated (24 h) OSCC cells after transfected with siFGFR3 or treated with rhFGF. D Western blotting was used to detect the expression of protein and phosphorylated protein of FGFR3, AKT and mTOR and apoptosis-related proteins in indicated treatment OSCC cells. *P < 0.05; **P < 0.01; ***P < 0.001

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Cancer Cell International

ISSN: 1475-2867

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