Skip to main content
Fig. 1 | Cancer Cell International

Fig. 1

From: Combinatorial targeting of menin and the histone methyltransferase DOT1L as a novel therapeutic strategy for treatment of chemotherapy-resistant ovarian cancer

Fig. 1

Evaluation of MEN1 expression and its “fitness” properties in OC cells. (A) Box plot showing MEN1 mRNA expression in ovarian tumors (red) and normal tissues (blue) (*** p ≤ 0.0005). (B) Rank order plot depicting distribution of standardized essentiality scores (average) for genes screened according to [32] in all OC cell lines. Box plots showing MEN1 gene essentiality score according to [32] in all OC cell lines (C) and in cell lines derived from different tumor types (D) (** p ≤ 0.005)

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us