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Fig. 4 | Cancer Cell International

Fig. 4

From: Exosomal LINC00460/miR-503-5p/ANLN positive feedback loop aggravates pancreatic cancer progression through regulating T cell–mediated cytotoxicity and PD-1 checkpoint

Fig. 4

Overexpression of miR-503-5p inhibits the malignant characteristics of PANC-1 cells. A The expression of miR-503-5p after transfection of miR-503-5p mimics/NC into PANC-1 cells was detected by qRT-PCR. B The viability (OD450) of PANC-1 cells was measured by MTT assay. C The proliferation of PANC-1 cells was determined by EdU assay (200 ×). D The apoptosis of PANC-1 cells was analyzed by flow cytometry assay. E The migration ability of PANC-1 cells was measured by transwell assay. F The invasion ability of PANC-1 cells was measured by transwell assay. G The protein levels of E-cadherin and N-cadherin were determined by Western blot. **P < 0.01 vs. the miR-NC group

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Cancer Cell International

ISSN: 1475-2867

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