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Fig. 5 | Cancer Cell International

Fig. 5

From: Exosomal circular RNA: a signature for lung cancer progression

Fig. 5

Illustration shows the connection between oncogenic signaling pathways and exosomal circRNAs in LC. CircRNA can promote tumor cell proliferation, invasion, migration, and survival by targeting particular genes and sponging various types of microRNAs, such as miR-101-3p, miR-498, miR-584-5p, miR-143-3p, and miR-600. CircRNA can act as an oncogene and promote the proliferation of cancer cells by involving in several essential signaling pathways in lung cancer, including EGFR/PI3K, miR-101-3p/KRAS, and miR-584-5p/E2F5 pathways

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