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Table 2 Expression of c-Rel, p50 and p65 in different stage of HPV16

From: Transcription factor c-Rel regulated by E5 affects the whole process after HPV16 infection through miR-133a-modulated feedback loop aim at mir-379-369 cluster

 

Negative Control (n = 37)

Early Infection 36)

Late Infection(n = 142)

hr-HPVs(-) without lesion

HPV16( +) cervix without lesion /LSIL

χ2

P

HPV16( +) HSIL/infiltrating carcinoma

χ2

P

c-Rel

 Negative (%)

26 (70.3)

17 (47.2)

5.693

0.017

38(26.8)

6.229

0.044

 Low (%)

6 (16.2)

5 (13.9)

38 (26.8)

 High (%)

5 (13.5)

14 (38.9)

66 (46.4)

NF-ĸB p65

 negative (%)

26 (70.3)

14 (38.8)

10.019

0.007

53 (37.4)

1.033

0.597

 Low (%)

9 (24.3)

11 (30.6)

55 (38.7)

 High (%)

2 (5.4)

11 (30.6)

34 (23.9)

NF-ĸB p50

 Negative (%)

23 (62.2)

19 (52.8)

0.753

0.686

40 (28.2)

8.014

0.018

 Low (%)

9 (24.3)

10 (27.8)

66 (46.4)

 High (%)

5 (13.5)

7 (19.4)

36 (25.4)