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Fig. 4 | Cancer Cell International

Fig. 4

From: Role of microRNA-34b-5p in cancer and injury: how does it work?

Fig. 4

Relationship of neurological diseases, genes and miR-34b-5p. A The target genes of miR-34b-5p in hippocampal damage. Grm1 Glutamate receptor, metabotropic 1. Syk Spleen tyrosine kinase. Cdc25a Cell division cycle 25 homolog A. Atxn3 Ataxin 3. BDNF Brain-derived neurotrophic factor. Cdkn1b Cyclin-dependent kinase inhibitor 1B. Ap1b1 Adaptor-related protein complex 1,beta 1 subunit. Ubl3 Ubiquitin-like 3. Agrn Agrin. Pdgfrb Platelet-derived growth factor receptor,beta polypeptide. B The target genes of miR-34b-5p in recurrent seizures. C The target genes of miR-34b-5p in Parkinnson’s disease. BACE1 β-Site amyloid precursor protein cleaving enzyme 1. iNOS inducible nitric oxide synthase. Glu glutamic acid. TH tyrosine hydroxylase. GSH-Px glutathione peroxidase. SOD superoxide dismuta. DA dopamine. MDA malondialdehyde. D The target genes of miR-34b-5p in major depressive disorder. VEGF-A vascular endothelial growth factor

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