Skip to main content
Fig. 8 | Cancer Cell International

Fig. 8

From: METTL3 promotes glycolysis and cholangiocarcinoma progression by mediating the m6A modification of AKR1B10

Fig. 8

METTL3 exerts an oncogenic role in CCA through AKR1B10. A The proliferation of RBE cells after knockdown of AKR1B10 upon METTL3 overexpression was detected by CCK8 assay. B Statistical results of Transwell assays. The numbers of migrating and invading cells were counted for comparison. C The migration and invasion of RBE cells after knockdown of AKR1B10 upon METTL3 overexpression were detected by Transwell assays. Scale bar: 100 μm. D Glucose uptake of RBE cells after knockdown of AKR1B10 upon METTL3 overexpression was detected using a commercial kit. E Lactate production in RBE cells after knockdown of AKR1B10 upon METTL3 overexpression. *Means P < 0.05, **means P < 0.01, ***means P < 0.001

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us