Fig. 1From: Transcriptomic landscape of TIMP3 oncosuppressor activity in thyroid carcinomaA TCGA-PTC tumors cohort stratified in four quartiles according to TIMP3 expression levels. B Methylation levels of TIMP3 gene in 121 quartile I and 122 quartile IV PTC cases. The average Beta values (y-axis) were calculated for each quartile (x-axis) on the four probes specific for the CpG Island nearer to TSS (left panel), and on all ten probes profiling TIMP3 global methylation status, also considering shore and shelf regions (right panel). Significant p-value of Wilcoxon rank sum test with continuity correction is reported for each analysisBack to article page