Table 3 Alterations in the expression of dystroglycanopathy-associated genes and proteins in human tumors

POMT1

mRNA

Underexpressed

Kidney

[76]

Overexpressed

Acute myeloid leukemia (AML)

[77]

POMT2

mRNA

Underexpressed

Kidney

[76]

Breast

[111]

Overexpressed

AML

[77]

DOLK

mRNA

Overexpressed

Breast

[112]

DPM1

mRNA

Overexpressed

Head and neck squamous cells

[113]

Esophagus

Colon

Rectum

Liver

Protein

Overexpressed

Liver

[113]

DPM2

mRNA

Overexpressed

Head and neck squamous cells

[113]

Esophagus

Colon

Rectum

Liver

Protein

Overexpressed

Liver

[113]

DPM3

mRNA

Overexpressed

Esophagus

[113]

Liver

Breast

Glioblastoma

Protein

Overexpressed

Liver

[113]

POMGNT1

mRNA

Overexpressed

Kidney

[76]

Glioma

[114]

AML

[77]

Protein

Overexpressed

Glioma

[114, 115]

POMGNT2

mRNA

Underexpressed

Kidney

[76]

Melanoma, uveal

[116]

B3GALNT2

mRNA

Underexpressed

Kidney

[76]

Rhabdomyosarcoma

[96]

Overexpressed

Liver

[117]

Breast

[118]

Protein

Overexpressed

Liver

[117]

POMK

mRNA

Underexpressed

Kidney

[76]

Overexpressed

Breast

[119]

Protein

Overexpressed

Breast

[119]

CRPPA

mRNA

Underexpressed

Kidney

[76, 120]

FKTN

mRNA

Overexpressed

Stomach

[121]

Liver

[122, 123]

AML

[77]

Protein

Overexpressed

Stomach

[121]

FKRP

mRNA

Underexpressed

Kidney

[76]

AML

[77]

B4GAT1

mRNA

Underexpressed

Pancreas

[124]

Overexpressed

Kidney

[76]

LARGE1

mRNA

Underexpressed

Colon

[106]

Prostate

[106]

Kidney

[76, 106]

Urinary bladder

[106]

Breast

Glioma

AML

[77]

Melanoma, skin

[106]

Rhabdomyosarcoma

[96]

Lung

[125]

Overexpressed

Head and neck sqamous cells

[126]

Liver

[127]

Protein

Underexpressed

Oral squamous cells

[81]

LARGE2

mRNA

Underexpressed

Prostate

[87]

Kidney

[76]

Overexpressed

Colorectal

[128]