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Fig. 3 | Cancer Cell International

Fig. 3

From: BI-847325, a selective dual MEK and Aurora kinases inhibitor, reduces aggressive behavior of anaplastic thyroid carcinoma on an in vitro three-dimensional culture

Fig. 3

The effect of BI-847325 on the protein levels of NIS and Tg in C643 and SW1736 ATC cell lines. NIS was quantified by flow cytometry 48 h after BI-847325 treatment. The Representative histograms indicate the FITC unspecific background fluorescence (isotype) and the level of NIS protein Pre- and post-treatment in C643 A and SW1736 B. C Graphical representation of the protein level of NIS based on flow cytometry in 48 h after BI-847325 treatment of ATC cell lines compared to untreated cells as control. Tg was measured using IRMA assay 48 h after BI-847325 treatment. D The concentration of Tg protein is indicated for C643 and SW1736 cells. Statistical significances are expressed as p < .05 (*); p < .01 (**); p < .001 (***); p < .0001 (****)

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Cancer Cell International

ISSN: 1475-2867

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