BI-847325, a selective dual MEK and Aurora kinases inhibitor, reduces aggressive behavior of anaplastic thyroid carcinoma on an in vitro three-dimensional culture

Table 1 The sequences of the primers

Gene	Sequence
AURKA	F: ATCGGCACCTGAAAATAATCC R: TCTTCCAAAGCCCACTGC
AURKB	F: CATCTGCACTTGTCCTCATG R: GAAGTGCCGCGTTAAGATG
BIM	F: CACTACCACCACTTGATTCTTG R: GGTCACACTCAGAACTTACATC
MDR1	F: TGGACAAGCACTGAAAGATAAG R: TTCCTCAAAGAGTTTCTGTATGG
MRP1	F: CCATCCACGACCCTAATCC R: CGCATTCCTTCTTCCAGTTC
NFκB2	F: GAGTTGCTACAACCCAGGTC R: ACAGTGGGATAGGTCTTTCG
P16	F: GAAGGTCCCTCAGACATCC R: AATGGACATTTACGGTAGTGG
Tg	F: GGTTCCTCGCAGTTCAATC R: GCCTTCAGCACAAGATGG
VEGF	F: ATCACGAAGTGGTGAAGTTC R: TGAGGTTTGATCCGCATAATC
NIS	F: CATCCTGAACCAAGTGACC R: TAGCATCACCACGACCTG
NFκB1	F: GTGCTGGAGTTCAGGATAACC R: GTGGATGATTGCTAAGTGTAA GAC
β-actin	F: CTTCCTTCCTGGGCATG R: GTCTTTGCGGATGTCCAC

AURKA Aurora Kinase A, AURKB Aurora Kinase B, AURKBC Aurora Kinase C, BIM BCL2 Like 11, MDR1 ATP Binding Cassette Subfamily B Member 1, MRP1 ATP Binding Cassette Subfamily C Member 1, NFκB1 Nuclear Factor Kappa B Subunit 1, NFκB2 Nuclear Factor Kappa B Subunit 2, NIS Sodium/Iodide Symporter, P16 Cyclin Dependent Kinase Inhibitor 2 A, p-H3 phospho-Histone H3, TFs Transcription Factors, Tg Thyroglobulin, VEGF Vascular Endothelial Growth Factor

ISSN: 1475-2867