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Fig. 2 | Cancer Cell International

Fig. 2

From: The anterior gradient homologue 2 (AGR2) co-localises with the glucose-regulated protein 78 (GRP78) in cancer stem cells, and is critical for the survival and drug resistance of recurrent glioblastoma: in situ and in vitro analyses

Fig. 2

UPR markers co-staining with CSC markers. The immunofluorescence images for AGR2 (red) co-localising with either Nestin (green), SSEA4 (green), or VIM (green); and GRP78 (green) co-localising with either SOX2 (red), FZD9 (red), or TUBB3 (red) in A) fresh frozen tissues, B) corresponding primary cell lines and C) Magnified images to show detail intracellular localization of the respective proteins in the cells. DAPI is shown in blue. All images were taken at 20 × magnification. D A barograph showing the percentages of double-positive cells for the aforementioned markers in the primary cell lines. Error bars indicate the data variability between counts for three independent experiments

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