Fig. 10

Mifepristone promotes the dissociation of PEO6 spheroids, incubated in adherent PEO6 conditioned media, to the organotypic model composed of fibroblasts embedded in collagen I and topped with a layer of mesothelial cells. PEO6 spheroids were treated with 20 µM of MF for 72 h prior to plating. Scale bar = 200 µm. Data shown represents the mean ± s.e.m. For panel C, **P < 0.01 compared to Vehicle. Statistical analysis was done using student t-test