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Table 1 The sequences of TIMP-2 targeted by Cas9

From: Knock down of TIMP-2 by siRNA and CRISPR/Cas9 mediates diverse cellular reprogramming of metastasis and chemosensitivity in ovarian cancer

Cas9-guided vector

Target Sequence (5′ → 3′)

Gene targeted

Exon

gRNA1

AGCAGCTGCAGGCGTCGGCC

TIMP-2

1

gRNA2

CGCACCCTGCGGCTGGCGCT

TIMP-2

1

Scramble control

GCACTACCAGAGCTAACTCA

None

N/A

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Cancer Cell International

ISSN: 1475-2867

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