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Fig. 3 | Cancer Cell International

Fig. 3

From: Therapeutic effect of a MUC1-specific monoclonal antibody-drug conjugates against pancreatic cancer model

Fig. 3

HzMUC1-MMAE induces cell cycle arrest at G2/M phase in pancreatic cancer cells. A Indicated pancreatic cell lines were treated with indicated concentrations of HzMUC1-MMAE for 24 h, fixed, and stained with Propidium iodide. G1, S, and G2/M phases of the cell cycle were analyzed by Flow cytometry using NovoExpress software. B Quantification of the flow cytometry analysis data from (A). The mean values from four different experiments were presented. The G2/M content of the HzMUC1-MMAE group was compared with that of vehicle control group. Statistical analyses were performed using One-way ANOVA with Bonferroni’s multiple comparision test, **P < 0.01, ***P < 0.001, ****P < 0.0001

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Cancer Cell International

ISSN: 1475-2867

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