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Table 1 Clinical data of patients included in the proteome comparison of GBM vs. non-malignant brain (resected from the same patient to approach the tumor site during surgery)

From: Changes in calpain-2 expression during glioblastoma progression predisposes tumor cells to temozolomide resistance by minimizing DNA damage and p53-dependent apoptosis

Patient

Sex

Age

Tumor

MGMT status

EGFR v III

IDH R132H

TP53

Ki67 [%]

1

M

72

Initial

Methylated

Negative

Negative

 +  + 

50

2

F

78

Initial

Methylated

Focal positive

Negative

 + 

7

3

F

79

Initial

Methylated

Positive

Negative

 +  + 

20

4

M

62

Initial

Unmethylated

Negative

Negative

 + 

30

5

M

63

Initial

Unmethylated

Negative

Negative

 + 

20

  1. TP53 status: +  + strong accumulation, + accumulation