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Fig. 2 | Cancer Cell International

Fig. 2

From: Molecular subtypes predict therapeutic responses and identifying and validating diagnostic signatures based on machine learning in chronic myeloid leukemia

Fig. 2

Analysis of immune cell infiltration and prediction of upstream regulatory network according to the DEGs. A GSEA analysis of enrichment pathways in the CML group. B GSEA analysis of enrichment pathways in the Normal group. C Differences in infiltration of 22 immune cells between CML and normal samples. D Differences in expression of immune checkpoints between CML and normal samples. E PPI network of the DEGs. F The subnetwork of the top 20 most connected genes in the PPI network. G Kinases and H transcription factors according to the predictions of the DEGs. I Regulatory network diagram according to the prediction of the DEGs. Nodes’ size is scaled proportional to the corresponding degree

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