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Fig. 3 | Cancer Cell International

Fig. 3

From: CAFs-derived rho-associated kinase1 mediated EMT to promote laryngeal squamous cell carcinoma metastasis

Fig. 3

CAFs-derived ROCK1 promoted the process of EMT of LSCC. (A. B. C. E). The expressions of E-cadherin and N-cadherin, Slug and Vimentin were detected via IF and Western Blot in Hep2/NFs/ROCK1, Hep2/NFs/vector, Hep2/CAFs/parental and Hep2/CAFs/si-ROCK1 cells. E-cadherin level was reduced in Hep2/NFs/ROCK1 cells, while it was increased in Hep2/CAFs/si-ROCK1 cells. The expressions of N-cadherin, Slug and Vimentin were increased in Hep2/NFs/ROCK1 cells, while they were reduced in Hep2/CAFs/si-ROCK1 cells. (D.F). Protein ratio in Hep2/NFs/ROCK1, Hep2/NFs/vector, Hep2/CAFs/parental and Hep2/CAFs/si-ROCK1 cells (*P < 0.05)

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