Fig. 6

MiR-3180 inhibits the proliferation, migration, and invasion of HCC cells by suppressing lipid synthesis and uptake. a Cell proliferation analysis of HepG2 cells transfected with the indicated expression vectors and treated with or without A939572 (15 μM) or SSO (50 μM). The expression of CD36 and SCD1 is shown in the right panel. b Wound healing analysis of HepG2 cells transfected and treated as in (a). Scale bar: 50 μm. Statistical analysis of relative migrations is shown in the lower panel. c Transwell analysis of HepG2 cells transfected and treated as in (a). Statistical analysis of relative invasion is shown in the lower panel. Scale bar: 20 μm. The data shown are presented as the mean ± SD of triplicate measurements with similar results. **p < 0.01