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Fig. 7 | Cancer Cell International

Fig. 7

From: Colorectal cancer-derived small extracellular vesicles induce TGFβ1-mediated epithelial to mesenchymal transition of hepatocytes

Fig. 7

sEVs isolated from CRC biopsies modulate the expression of mesenchymal and epithelial markers in hepatocytes. a Representative TEM micrograph of sEVs isolated from CRC biopsy (CRC/B1 in Table 2). Scale bars: 1 µm and 100 nm. b Confocal microscopy analysis of Vimentin (red) and CK8/18 (green) in hepatocytes treated with sEVs isolated from a CRC biopsy (CRC/B2 in Table 2; CRC/B2_sEVs) and from the corresponding non-CRC mucosa (NCRC/B2 in Table 2; NCRC/B2_sEVs) for 24 h; nuclei are in blue. Untreated cells are indicated as control (Ctrl)

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Cancer Cell International

ISSN: 1475-2867

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