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Fig. 6 | Cancer Cell International

Fig. 6

From: Syndecan-1 as an immunogene in Triple-negative breast cancer: regulation tumor-infiltrating lymphocyte in the tumor microenviroment and EMT by TGFb1/Smad pathway

Fig. 6

The effect of SDC1 on breast cancer cell proliferation and migration. A Relative SDC1 mRNA expression after knockdown and overexpression. B Relative SDC1 protein expression after knockdown and overexpression. A CCK-8 assay evaluated the effects of SDC1 on cell proliferation after the C knockdown and D overexpression of SDC1. E Transwell assay determined that SDC1 knockdown promoted the invasion of MDA-MB-231 cells. F The protein levels of EMT-related proteins. G Protein expression in the TGF-β1/Smad signaling pathway. Results with P < 0.05 were considered statistically significant. An unpaired t-test was used for data analysis *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001

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