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  1. Content type: Primary research

    The effects of the vitamin A metabolite retinoic acid (RA) are mediated at the transcriptional level by retinoic acid receptors (RAR). These proteins are part of a superfamily of transcription factors which ac...

    Authors: David L Crowe and Randie Kim

    Citation: Cancer Cell International 2002 2:15

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  2. Content type: Primary research

    We previously reported the usefulness of the αGal epitope as a target molecule for gene therapy against cancer. To induce cancer cell specific transcription of the αGal epitope, an expression vector which synt...

    Authors: Tokihiko Sawada, Osamu Yamada, Naoko Yoshimura, Keiko Hatori, Shohei Fuchinoue and Satoshi Teraoka

    Citation: Cancer Cell International 2002 2:14

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  3. Content type: Hypothesis

    A kinetic model has been developed to study cancer growth. Cancer growth has been considered as interaction between various independent but interacting compartments. The model considers cell growth and metasta...

    Authors: Siddhartha Jain

    Citation: Cancer Cell International 2002 2:13

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  4. Content type: Primary research

    The C1D gene is expressed in a broad spectrum of mammalian cells and tissues but its product induces apoptotic cell death when exceeding a critical level. Critical levels are achieved in a fraction of cells by...

    Authors: Karsten Rothbarth, Hermann Stammer and Dieter Werner

    Citation: Cancer Cell International 2002 2:12

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  5. Content type: Primary research

    It is postulated that the unusual manifestations of Kaposis's sarcoma cells in nonendothelial brain tissues and on eyeballs in advanced acquired immune deficiency syndrome (AIDS) cases are metastasized AIDS-Ka...

    Authors: Mahruf U Rahman and Amitabha Mazumder

    Citation: Cancer Cell International 2002 2:11

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  6. Content type: Primary research

    Supplementing mice with high levels of dietary n-3 polyunsaturated fatty acids (PUFAs) increases the n-3 PUFAs in cell membranes, increases the susceptibility of the cells for lipid peroxidation (LPO) and decr...

    Authors: W Elaine Hardman, Jesus Munoz Jr and Ivan L Cameron

    Citation: Cancer Cell International 2002 2:10

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  7. Content type: Primary research

    Isopeptides (ε-peptides) of lysine, with a given Mw and low polydispersity (10–400 units), were synthesized to study the relationship between their chemical structure and biological effect. The designed compou...

    Authors: B Szende, Gy Szökán, E Tyihá, K Pál, R Gáborjányi, M Almás and A R Khlafulla

    Citation: Cancer Cell International 2002 2:4

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  8. Content type: Primary research

    The issue remains unresolved as to whether low frequency magnetic fields can affect cell behaviour, with the possibility that they may be in part responsible for the increased incidence of leukaemia in parts o...

    Authors: Paul A Harris, Justin Lamb, Brian Heaton and Denys N Wheatley

    Citation: Cancer Cell International 2002 2:3

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  9. Content type: Primary research

    The p16INK4A gene product halts cell proliferation by preventing phosphorylation of the Rb protein. The p16INK4a gene is often deleted in human glioblastoma multiforme, contributing to unchecked Rb phosphorylatio...

    Authors: Bryan E Strauss, Ricardo BV Fontes, Claudimara FP Lotfi, Ana Lucia Skorupa, Ione Bartol, José Cipolla-Neto and Eugenia Costanzi-Strauss

    Citation: Cancer Cell International 2002 2:2

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  10. Content type: Primary research

    We describe an alternative method to determine mRNA half-life (t1/2) based on the Real-Time RT-PCR procedure. This approach was evaluated by using the β-actin gene as a reference molecule for measuring of mRNA st...

    Authors: Guy J Leclerc, Gilles M Leclerc and Julio C Barredo

    Citation: Cancer Cell International 2002 2:1

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  11. Content type: Primary research

    5-AzaCytidine (AzaC) is a DNA demethylating drugs that has been shown to inhibit cell growth and to induce apoptosis in certain cancer cells. Induced expression of the galectin1 (Gal1) protein, a galactoside-b...

    Authors: Florence Poirier, Philippe Bourin, Dominique Bladier, Raymonde Joubert-Caron and Michel Caron

    Citation: Cancer Cell International 2001 1:2

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  12. Content type: Review

    Mitotic death is a delayed response of p53 mutant tumours that are resistant to genotoxic damage. Questions surround why this response is so delayed and how its mechanisms serve a survival function. After unco...

    Authors: Jekaterina Erenpreisa and M S Cragg

    Citation: Cancer Cell International 2001 1:1

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