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  1. d-α-tocopherol is a naturally occurring form of vitamin E not previously known to have antitumor activity. Synthetic vitamin E (sE) is a commonly used dietary supplement consisting of a mixture of d-α-tocopher...

    Authors: Ivan L Cameron, Jesus Munoz, Christopher J Barnes and W Elaine Hardman
    Citation: Cancer Cell International 2003 3:3
  2. Eukaryotic initiation factor 4E (eIF4E) is essential for cap-dependent initiation of translation. Cell proliferation is associated with increased activity of eIF4E and elevated expression of eIF4E leads to tum...

    Authors: Hong Jiang, Jennifer Coleman, Robin Miskimins and W Keith Miskimins
    Citation: Cancer Cell International 2003 3:2
  3. Since lung epithelial cells are constantly being exposed to reactive oxygen intermediates (ROIs), the alveolar surface is a major site of oxidative stress, and each cell type may respond differently to oxidati...

    Authors: Yoshihiro Fujii, Katsuyuki Tomita, Hiroyuki Sano, Akira Yamasaki, Yutaka Hitsuda, Ian M Adcock and Eiji Shimizu
    Citation: Cancer Cell International 2002 2:16
  4. The effects of the vitamin A metabolite retinoic acid (RA) are mediated at the transcriptional level by retinoic acid receptors (RAR). These proteins are part of a superfamily of transcription factors which ac...

    Authors: David L Crowe and Randie Kim
    Citation: Cancer Cell International 2002 2:15
  5. We previously reported the usefulness of the αGal epitope as a target molecule for gene therapy against cancer. To induce cancer cell specific transcription of the αGal epitope, an expression vector which synt...

    Authors: Tokihiko Sawada, Osamu Yamada, Naoko Yoshimura, Keiko Hatori, Shohei Fuchinoue and Satoshi Teraoka
    Citation: Cancer Cell International 2002 2:14
  6. A kinetic model has been developed to study cancer growth. Cancer growth has been considered as interaction between various independent but interacting compartments. The model considers cell growth and metasta...

    Authors: Siddhartha Jain
    Citation: Cancer Cell International 2002 2:13
  7. The C1D gene is expressed in a broad spectrum of mammalian cells and tissues but its product induces apoptotic cell death when exceeding a critical level. Critical levels are achieved in a fraction of cells by...

    Authors: Karsten Rothbarth, Hermann Stammer and Dieter Werner
    Citation: Cancer Cell International 2002 2:12
  8. It is postulated that the unusual manifestations of Kaposis's sarcoma cells in nonendothelial brain tissues and on eyeballs in advanced acquired immune deficiency syndrome (AIDS) cases are metastasized AIDS-Ka...

    Authors: Mahruf U Rahman and Amitabha Mazumder
    Citation: Cancer Cell International 2002 2:11
  9. Supplementing mice with high levels of dietary n-3 polyunsaturated fatty acids (PUFAs) increases the n-3 PUFAs in cell membranes, increases the susceptibility of the cells for lipid peroxidation (LPO) and decr...

    Authors: W Elaine Hardman, Jesus Munoz Jr and Ivan L Cameron
    Citation: Cancer Cell International 2002 2:10
  10. Isopeptides (ε-peptides) of lysine, with a given Mw and low polydispersity (10–400 units), were synthesized to study the relationship between their chemical structure and biological effect. The designed compou...

    Authors: B Szende, Gy Szökán, E Tyihá, K Pál, R Gáborjányi, M Almás and A R Khlafulla
    Citation: Cancer Cell International 2002 2:4
  11. The issue remains unresolved as to whether low frequency magnetic fields can affect cell behaviour, with the possibility that they may be in part responsible for the increased incidence of leukaemia in parts o...

    Authors: Paul A Harris, Justin Lamb, Brian Heaton and Denys N Wheatley
    Citation: Cancer Cell International 2002 2:3
  12. The p16INK4A gene product halts cell proliferation by preventing phosphorylation of the Rb protein. The p16INK4a gene is often deleted in human glioblastoma multiforme, contributing to unchecked Rb phosphorylatio...

    Authors: Bryan E Strauss, Ricardo BV Fontes, Claudimara FP Lotfi, Ana Lucia Skorupa, Ione Bartol, José Cipolla-Neto and Eugenia Costanzi-Strauss
    Citation: Cancer Cell International 2002 2:2
  13. We describe an alternative method to determine mRNA half-life (t1/2) based on the Real-Time RT-PCR procedure. This approach was evaluated by using the β-actin gene as a reference molecule for measuring of mRNA st...

    Authors: Guy J Leclerc, Gilles M Leclerc and Julio C Barredo
    Citation: Cancer Cell International 2002 2:1
  14. 5-AzaCytidine (AzaC) is a DNA demethylating drugs that has been shown to inhibit cell growth and to induce apoptosis in certain cancer cells. Induced expression of the galectin1 (Gal1) protein, a galactoside-b...

    Authors: Florence Poirier, Philippe Bourin, Dominique Bladier, Raymonde Joubert-Caron and Michel Caron
    Citation: Cancer Cell International 2001 1:2
  15. Mitotic death is a delayed response of p53 mutant tumours that are resistant to genotoxic damage. Questions surround why this response is so delayed and how its mechanisms serve a survival function. After unco...

    Authors: Jekaterina Erenpreisa and M S Cragg
    Citation: Cancer Cell International 2001 1:1

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