Skip to main content

Articles

Page 2 of 39

  1. Cervical cancer (CC) is the second leading cause of cancer deaths in women worldwide, still lacking effective biomarkers and therapies for diagnosis and treatment. CircRNAs are a class of endogenous RNAs that ...

    Authors: Shuaisai Zhang, Zhengli Chen, Jinxue Sun, Na An and Qinghua Xi

    Citation: Cancer Cell International 2020 20:287

    Content type: Primary research

    Published on:

  2. As one of the most lethal cancers, pancreatic cancer has been characterized by abundant supportive tumor-stromal cell microenvironment. Although the advent of tumor-targeted immune checkpoint blockers has brou...

    Authors: Tong Li, Qiaofei Liu, Ronghua Zhang, Quan Liao and Yupei Zhao

    Citation: Cancer Cell International 2020 20:341

    Content type: Primary research

    Published on:

  3. Long non-coding RNAs (lncRNAs) have been certified to be involved in the occurrence and growth of diverse cancers, including CRC. The purpose of the research was to explore the effects of lncRNA KCNQ1 overlapp...

    Authors: Xing Liu, Yexiang Zhang, Yan Wang, Chao Bian and Fengji Wang

    Citation: Cancer Cell International 2020 20:340

    Content type: Primary research

    Published on:

  4. GATA binding protein 3 (GATA3) and miR-29b are related to colorectal cancer (CRC). The current study explored the regulatory relationship between GATA3 and miR-29b, and the mechanism of the two in the drug res...

    Authors: Wei Wang, Mei Wang, Jing Xu, Fei Long and Xianbao Zhan

    Citation: Cancer Cell International 2020 20:339

    Content type: Primary research

    Published on:

  5. Cell autophagy has been proposed to be involved in drug resistance therapy. However, how the long non-coding RNA (lncRNA) reduces risks of drug resistance in renal cancer (RC) cells needs a thorough inquiry. T...

    Authors: Dechao Li, Changfu Li, Yongsheng Chen, Lichen Teng, Yan Cao, Wentao Wang, Hongxin Pan, Yongpeng Xu and Dan Yang

    Citation: Cancer Cell International 2020 20:338

    Content type: Primary research

    Published on:

  6. Glioblastoma multiforme (GBM) is the most common and lethal type of primary brain tumor. More than half of GBMs contain mutation(s) of PTEN/PI3K/AKT, making inhibitors targeting the PI3K pathway very attractiv...

    Authors: Zhen Chen, Chao Chen, Tingting Zhou, Chao Duan, Qianqian Wang, Xiaohui Zhou, Xia Zhang, Fangrong Wu, Yunfen Hua and Fan Lin

    Citation: Cancer Cell International 2020 20:337

    Content type: Primary research

    Published on:

  7. Accumulating data suggested that circular RNAs (circRNAs) played important roles in the development of human cancer. However, the potential mechanism of circRNAs in ovarian cancer remains unclear.

    Authors: Chunli Lin, Xiaofeng Xu, Qiumin Yang, Lu Liang and Shulin Qiao

    Citation: Cancer Cell International 2020 20:336

    Content type: Primary research

    Published on:

  8. Antisense non-coding RNA in the INK4 locus (ANRIL) is of great importance in cell biological behaviors, and ANRIL functions in many kinds of cancers including leukemia. However, the mechanism of ANRIL in the p...

    Authors: Gang Li, Lan Gao, Jing Zhao, Dejun Liu, Hui Li and Min Hu

    Citation: Cancer Cell International 2020 20:335

    Content type: Primary research

    Published on:

  9. One of the main reasons for the failure of prostate cancer (PCa) treatment is the generation of chemoresistance. Circular RNA hsa_circ_0000735 (hsa_circ_0000735) is connected with the progression of cancer. Ne...

    Authors: Yisheng Gao, Jie Liu, Jing Huan and Fengyuan Che

    Citation: Cancer Cell International 2020 20:334

    Content type: Primary research

    Published on:

  10. Cervical cancer (CC) is a malignant tumor found in the lowermost part of the womb. Evolving studies on CC have reported that circRNA plays a crucial role in CC progression. In this study, we investigated the m...

    Authors: Xinhua Qu, Liumei Zhu, Linlin Song and Shaohua Liu

    Citation: Cancer Cell International 2020 20:333

    Content type: Primary research

    Published on:

  11. Fatty acid synthase (FASN) is highly expressed in various types of cancer and has an important role in carcinogenesis and metastasis. To clarify the mechanisms of FASN in liver cancer invasion and metastasis, ...

    Authors: Juan Huang, Yao Tang, Xiaoqin Zou, Yi Lu, Sha She, Wenyue Zhang, Hong Ren, Yixuan Yang and Huaidong Hu

    Citation: Cancer Cell International 2020 20:332

    Content type: Primary research

    Published on:

  12. Although major driver gene have been identified, the complex molecular heterogeneity of renal cell cancer (RCC) remains unclear. Therefore, more relevant genes need to be identified to explain the pathogenesis...

    Authors: Yeda Chen, Di Gu, Yaoan Wen, Shuxin Yang, Xiaolu Duan, Yongchang Lai, Jianan Yang, Daozhang Yuan, Aisha Khan, Wenqi Wu and Guohua Zeng

    Citation: Cancer Cell International 2020 20:331

    Content type: Primary research

    Published on:

  13. The incidence of lung squamous cell carcinoma (LUSC) increased substantially in recent years. Systematical investigation of the immunogenomic pattern is critical to improve the prognosis of LUSC.

    Authors: Jianguo Zhang, Jianzhong Zhang, Cheng Yuan, Yuan Luo, Yangyi Li, Panpan Dai, Wenjie Sun, Nannan Zhang, Jiangbo Ren, Junhong Zhang, Yan Gong and Conghua Xie

    Citation: Cancer Cell International 2020 20:330

    Content type: Primary research

    Published on:

  14. Endometrial cancer (EnCa) ranks fourth in menace within women’s malignant tumors. Large numbers of studies have proven that functional genes can change the process of tumors by regulating the cell cycle, there...

    Authors: Jinhui Liu, Jie Mei, Siyue Li, Zhipeng Wu and Yan Zhang

    Citation: Cancer Cell International 2020 20:329

    Content type: Primary research

    Published on:

  15. Despite decades of therapeutic trials, effective diagnosis, many drugs available and numerous studies on breast cancer, it remains the deadliest cancer in women. In order to choose the most appropriate treatme...

    Authors: Augustin Le Naour, Yvonne Koffi, Mariane Diab, Delphine Le Guennec, Stéphanie Rougé, Sahar Aldekwer, Nicolas Goncalves-Mendes, Jérémie Talvas, Marie-Chantal Farges, Florence Caldefie-Chezet, Marie-Paule Vasson and Adrien Rossary

    Citation: Cancer Cell International 2020 20:328

    Content type: Primary research

    Published on:

  16. Long non-coding RNAs (lncRNAs) has been extensively reported play important roles in regulating the development and progression of cancers, including Glioblastoma (GBM). LINC01426 is a novel lncRNA that has be...

    Authors: Jingwei Cao, Zhanbin Tang and Zhiqiang Su

    Citation: Cancer Cell International 2020 20:327

    Content type: Primary research

    Published on:

  17. The outlook for new therapeutic approaches is pivotal to ameliorate the deterioration caused by the abrogated Wnt signaling. Long non-coding RNAs (lncRNAs) are tiny molecules that have begun emerging as vital mol...

    Authors: Zeeshan Javed, Khushbukhat Khan, Haleema Sadia, Shahid Raza, Bahare Salehi, Javad Sharifi-Rad and William C. Cho

    Citation: Cancer Cell International 2020 20:326

    Content type: Review

    Published on:

  18. Methylation of histone 3 at lysine 9 (H3K9) and DNA methylation are epigenetic marks correlated with genes silencing. The tumor microenvironment significantly influences therapeutic responses and clinical outc...

    Authors: Li Zhang, Sijuan Tian, Minyi Zhao, Ting Yang, Shimin Quan, Qing Yang, Lihua Song and Xiaofeng Yang

    Citation: Cancer Cell International 2020 20:325

    Content type: Primary research

    Published on:

  19. Cholangiocarcinoma (CCA) is a mortal cancer with high mortality, whereas the function and mechanism of occurrence and progression of CCA are still mysterious. Long non-coding RNAs (lncRNAs) could function as i...

    Authors: Lining Huang, Xingming Jiang, Zhenglong Li, Jinglin Li, Xuan Lin, Zengtao Hu and Yunfu Cui

    Citation: Cancer Cell International 2020 20:324

    Content type: Primary research

    Published on:

  20. Prostate cancer (PCa) is a malignant heterogeneous tumor that threatens men’s health. Long non-coding RNA activated by DNA damage (NORAD) and microRNA-495-3p (miR-495-3p) have been revealed to be concerned wit...

    Authors: Fengling Chen, Ling Liu and Shuya Wang

    Citation: Cancer Cell International 2020 20:323

    Content type: Primary research

    Published on:

  21. Long non-coding RNAs (lncRNAs) have been defined as vital regulators in the progression of human cancers, including colorectal cancer (CRC). Long intergenic non-protein coding RNA 667 (LINC00667) is a tumor pr...

    Authors: Juan Yu, Furang Wang, Jun Zhang, Jing Li, Xiaoguang Chen and Guangsen Han

    Citation: Cancer Cell International 2020 20:322

    Content type: Primary research

    Published on:

  22. Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) play vital roles in human cancers. Nevertheless, the effects of lncRNAs and miRNAs on breast cancer (BC) remain to be further investigated. This study was d...

    Authors: Shaoqiang Cheng, Bingshu Xia, Hongbin Li, Yuying Li, Xinxin Lv, Yue Zhang and Yuanxi Huang

    Citation: Cancer Cell International 2020 20:321

    Content type: Primary research

    Published on:

  23. Breast cancer (BC) is a common malignancy worldwide. It has been reported that long non-coding RNA (lncRNA) HOX transcript antisense RNA (HOTAIR) is abnormally expressed in BC. However, the role of HOTAIR in t...

    Authors: Yuanyuan Wang, Guoliang Gong, Jingyun Xu, Yuanxin Zhang, Shenggui Wu and Shaohong Wang

    Citation: Cancer Cell International 2020 20:320

    Content type: Primary research

    Published on:

  24. Long noncoding RNA (lncRNA) is generally identified as competing endogenous RNA (ceRNA) that plays a vital role in the pathogenesis of kidney renal clear cell carcinoma (KIRC), the most common subtype of renal...

    Authors: Di Zhang, Song Zeng and Xiaopeng Hu

    Citation: Cancer Cell International 2020 20:319

    Content type: Primary research

    Published on:

  25. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Yang Hu, Hong Xie, Yankun Liu, Weiying Liu, Min Liu and Hua Tang

    Citation: Cancer Cell International 2020 20:318

    Content type: Correction

    Published on:

    The original article was published in Cancer Cell International 2017 17:36

  26. Papillary renal cell carcinoma (pRCC) accounting for near 20% of renal cell carcinoma is the second most common histological subtype. MiRNAs have been demonstrated to played significant roles on predicting pro...

    Authors: Ge Li, Haifan Yang, Yong Cheng, Xin Zhao, Xu Li and Rui Jiang

    Citation: Cancer Cell International 2020 20:317

    Content type: Primary research

    Published on:

  27. Cell cycle dysregulation plays a key role in the pathogenesis of malignant tumors. As a part of the CDK-activating kinase (CAK) trimeric complex, cyclin H is necessary to regulate the cell cycle and proliferat...

    Authors: Chen Peng, Yansong Yang, Li Ji, Panpan Yang, Xiaoqing Yang and Yuquan Zhang

    Citation: Cancer Cell International 2020 20:316

    Content type: Primary research

    Published on:

  28. Accumulating amount of evidence has highlighted the important roles of long non-coding RNAs (lncRNAs) acting as competing endogenous RNAs (ceRNAs) in tumor pathogenesis. However, the roles of long non coding R...

    Authors: Zhichen Kang, Lixin Guo, Zhuo Zhu and Rongfeng Qu

    Citation: Cancer Cell International 2020 20:315

    Content type: Primary research

    Published on:

  29. Although the medical level is constantly improving, cancer is still a major disease that threatens human health, and very effective treatments have not been found. In recent years, studies have found that four...

    Authors: Yaoyue Qi, Hui Li, Jing Lv, Weiwei Qi, Liwei Shen, Shihai Liu, Aiping Ding, Gongjun Wang, Libin Sun and Wensheng Qiu

    Citation: Cancer Cell International 2020 20:314

    Content type: Primary research

    Published on:

  30. The aim of this study was to investigate the association between telomerase reverse transcriptase (TERT) gene polymorphisms and acute myeloid leukemia (AML) susceptibility in a Chinese Han population.

    Authors: Yong Tong, Yinzhou Xiang, Bao Li, Shijie Bao, Ying Zhou, Wen Yuan, Yu Ling, Dan Hao, Huamin Zhu and Zhiqiang Sun

    Citation: Cancer Cell International 2020 20:313

    Content type: Primary research

    Published on:

  31. Prostate cancer (PCa) is the second cause of cancer related death in North American men. Androgens play an important role in its progression by regulating the expression of several genes including fusion ones ...

    Authors: Carlos D. Cruz-Hernández, Marian Cruz-Burgos, Sergio A. Cortés-Ramírez, Alberto Losada-García, Ignacio Camacho-Arroyo, Patricia García-López, Elizabeth Langley, Vanessa González-Covarrubias, Monserrat Llaguno-Munive, Martha E. Albino-Sánchez, José L. Cruz-Colín, Carlos Pérez-Plasencia, Fredy O. Beltrán-Anaya and Mauricio Rodríguez-Dorantes

    Citation: Cancer Cell International 2020 20:312

    Content type: Primary research

    Published on:

  32. Long noncoding ribonucleic acid (lncRNA) promoter methylation is closely related to the occurrence and development of hepatocellular carcinoma (HCC). Thus, we aim to screen and verify the lncRNA promoter methy...

    Authors: Zhuo Lin, Xiaofeng Ni, Shengjie Dai, Hao Chen, Jianhui Chen, Boda Wu, Jianyang Ao, Keqing Shi and Hongwei Sun

    Citation: Cancer Cell International 2020 20:311

    Content type: Primary research

    Published on:

  33. Glioblastoma (GBM) is the most common primary malignant brain tumor in adults with a poor prognosis. DEPDC1B (DEP domain-containing protein 1B) has been shown to be associated with some types of malignancies. ...

    Authors: Xu Chen, Zheng-Qian Guo, Dan Cao, Yong Chen and Jian Chen

    Citation: Cancer Cell International 2020 20:310

    Content type: Primary research

    Published on:

  34. Ovarian serous cystadenocarcinoma (OSC) is the most common and lethal gynecological cancer in women worldwide; however, biomarkers to diagnose and predict prognosis of OSC remain limited. Therefore, the presen...

    Authors: Wei Huang, Yongjian Zhang, Ye Xu, Shaoyou Yang, Bing Li, Lan Huang and Ge Lou

    Citation: Cancer Cell International 2020 20:309

    Content type: Primary research

    Published on:

  35. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Rustelle Janse van Vuuren, Mandie Botes, Tamarin Jurgens, Anna Margaretha Joubert and Iman van den Bout

    Citation: Cancer Cell International 2020 20:308

    Content type: Correction

    Published on:

    The original article was published in Cancer Cell International 2019 19:1

  36. Although the fact that long non-coding RNA MCM3AP antisense RNA 1 (MCM3AP-AS1) is oncogenic in several cancers is well documented, very few researchers investigate its expression and function in prostate cancer.

    Authors: Jie Wu, Yalin Lv, Yujun Li, Yanxia Jiang, Lili Wang, Xiangyan Zhang, Mengqi Sun, Yuwei Zou, Jin Xu and Li Zhang

    Citation: Cancer Cell International 2020 20:307

    Content type: Primary research

    Published on:

  37. Autophagy is associated with cancer development. Autophagy-related genes play significant roles in endometrial cancer (EC), a major gynecological malignancy worldwide, but little was known about their value as...

    Authors: Hui Wang, Xiaoling Ma, Jinhui Liu, Yicong Wan, Yi Jiang, Yankai Xia and Wenjun Cheng

    Citation: Cancer Cell International 2020 20:306

    Content type: Primary research

    Published on:

  38. Osteosarcoma (OS) is the most common bone malignant tumor in children, youth, and adolescents. Circular RNA hsa_circ_0005909 (circ_0005909) is involved in the progression of OS. Nevertheless, there are few rep...

    Authors: Shuai Ding, Guangquan Zhang, Yanzheng Gao, Shulian Chen and Chen Cao

    Citation: Cancer Cell International 2020 20:305

    Content type: Primary research

    Published on:

  39. It has been widely reported that the expression levels of SNHG20 are elevated in diverse types of cancers, indicating that SNHG20 may participate in cancer initiation and development. Besides, accumulating evi...

    Authors: Hanlong Zhu, Si Zhao, Ruonan Jiao, Huishan Wang, Ruiyi Tang, Xiaochao Wu, Fei Wang, Xianxiu Ge, Quanpeng Li and Lin Miao

    Citation: Cancer Cell International 2020 20:304

    Content type: Review

    Published on:

  40. Gastric cancer (GC) is the leading cause of death worldwide and is closely related to metastasis. MRTF-A is one of the most well-characterized genetic markers in cancer. However, the mechanism whereby MRTF-A m...

    Authors: Libin Yin, Tao Liu, Chenyao Li, Guoqiang Yan, Chao Li, Jiantao Zhang and Lei Wang

    Citation: Cancer Cell International 2020 20:303

    Content type: Primary research

    Published on:

  41. Bladder cancer (BCa) is one of the important tumors that have been proven to be treatable with immunotherapy. This study aims to identify and validate a molecular prognostic index of BCa based on immunogenomic...

    Authors: Ning Xu, Zhi-Bin Ke, Xiao-Dan Lin, Ye-Hui Chen, Yu-Peng Wu, Yu Chen, Ru-Nan Dong, Shao-Hao Chen, Xiao-Dong Li, Yong Wei, Qing-Shui Zheng, Yun-Zhi Lin and Xue-Yi Xue

    Citation: Cancer Cell International 2020 20:302

    Content type: Primary research

    Published on:

  42. Researches validate that circular RNAs (circRNAs) are dysregulated in a variety of malignancies and play an important role in regulating the malignant phenotype of tumor cells. Nevertheless, the role of circ_0...

    Authors: Li Zhang, Jie Wu, Yujun Li, Yanxia Jiang, Lili Wang, Yunqing Chen, Yalin Lv, Yuwei Zou and Xiaoyan Ding

    Citation: Cancer Cell International 2020 20:301

    Content type: Primary research

    Published on:

  43. The mechanisms of neuronal protein γ-synuclein (SNCG) in the malignancy of oral squamous cell carcinoma (OSCC) are not clear. This study tested the hypothesis that SNCG is involved in nicotine-induced malignan...

    Authors: Chia-Chen Hsu, Yu-Fu Su, Kuo-Yang Tsai, Feng-Chih Kuo, Chi-Fu Chiang, Chu-Yen Chien, Ying-Chen Chen, Chien-Hsing Lee, Yu-Chiao Wu, Kun Wang, Shyun-Yeu Liu and Yi-Shing Shieh

    Citation: Cancer Cell International 2020 20:300

    Content type: Primary research

    Published on:

  44. Small nucleolar RNAs (snoRNAs) are a new non-coding RNAs (ncRNAs), which have not been widely investigated and are identified to be involved in tumorigenesis. But the function of snoRNAs in BLCA has not been r...

    Authors: Rui Cao, Bo Ma, Lushun Yuan, Gang Wang and Ye Tian

    Citation: Cancer Cell International 2020 20:299

    Content type: Primary research

    Published on:

  45. Cancer remains one of the major culprits causing disease-related deaths and leads to a high morbidity and similar mortality. Insidious onset, difficult early detection and a lack of broad-spectrum and effectiv...

    Authors: Yizhi Wang, Li Zhou, Jun Lu, Bolun Jiang, Chengxi Liu and Junchao Guo

    Citation: Cancer Cell International 2020 20:298

    Content type: Review

    Published on:

  46. Pancreatic ductal adenocarcinoma (PDAC), a subtype of pancreatic cancer, is a malignant tumor with unfavorable prognosis. Despite accumulating researches have made efforts on finding novel therapeutic methods ...

    Authors: Liping Wu, Yongcun Liu, Cheng Guo and Yuan Shao

    Citation: Cancer Cell International 2020 20:296

    Content type: Primary research

    Published on:

  47. Hepatocellular carcinoma (HCC) is a common malignant tumor in China. Advanced treatment like transcatheter hepatic arterial chemoembolization (TACE) has prolonged the lives of many HCC patients. However, the p...

    Authors: Xialei Liu, Lewei Yang, Dong Jiang, Wuzhu Lu and Yongyu Zhang

    Citation: Cancer Cell International 2020 20:295

    Content type: Primary research

    Published on:

  48. Thyroid cancer (TC) is the most frequent endocrine malignancy. Long noncoding RNAs (lncRNAs) have been confirmed to act as significant roles in tumor development. The role of lncRNA TMPO-AS1 in TC is still unc...

    Authors: Zhenyu Li, Yun Feng, Zhen Zhang, Xiaozhong Cao and Xiubo Lu

    Citation: Cancer Cell International 2020 20:294

    Content type: Primary research

    Published on:

Annual Journal Metrics

Institutional membership

Visit the membership page to check if your institution is a member and learn how you could save on article-processing charges (APCs).

Funding your APC

​​​​​​​Open access funding and policy support by SpringerOpen​​

​​​​We offer a free open access support service to make it easier for you to discover and apply for article-processing charge (APC) funding. Learn more here