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  1. Transgelin, an actin-binding protein, is associated with cytoskeleton remodeling. Findings from our previous studies demonstrated that transgelin was up-regulated in node-positive colorectal cancer (CRC) versu...

    Authors: Zhen-xian Lew, Hui-min Zhou, Yuan-yuan Fang, Zhen Ye, Wa Zhong, Xin-yi Yang, Zhong Yu, Dan-yu Chen, Si-min Luo, Li-fei Chen and Ying Lin

    Citation: Cancer Cell International 2020 20:366

    Content type: Primary research

    Published on:

  2. Cisplatin resistance of ovarian yolk sac tumors (oYST) is a clinical challenge due to dismal patient prognosis, even though the disease is extremely rare. We investigated potential association between cisplati...

    Authors: Silvia Schmidtova, Lambert C. J. Dorssers, Katarina Kalavska, Ad J. M. Gillis, J. Wolter Oosterhuis, Hans Stoop, Svetlana Miklikova, Zuzana Kozovska, Monika Burikova, Katarina Gercakova, Erika Durinikova, Michal Chovanec, Michal Mego, Lucia Kucerova and Leendert H. J. Looijenga

    Citation: Cancer Cell International 2020 20:364

    Content type: Primary research

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  3. Human papillomaviruses (HPVs) and Epstein–Barr virus (EBV), known oncoviruses, can be co-present and cooperate in the initiation and/or progression of human carcinomas, including head and neck. Based on this f...

    Authors: Hamda Al-Thawadi, Ishita Gupta, Ayesha Jabeen, Faruk Skenderi, Tahar Aboulkassim, Amber Yasmeen, Mohammed I. Malki, Gerald Batist, Semir Vranic and Ala-Eddin Al Moustafa

    Citation: Cancer Cell International 2020 20:361

    Content type: Primary research

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  4. Hepatocellular carcinoma (HCC) is the most common malignant heterogeneous disease in primary liver tumors. Circular RNA hsa_circ_0000517 (hsa_circ_0000517) is connected with HCC prognosis. Nevertheless, there ...

    Authors: Shuwei He, Zhengwu Guo, Qian Kang, Xu Wang and Xingmin Han

    Citation: Cancer Cell International 2020 20:360

    Content type: Primary research

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  5. Cervical cancer (CC) is the 4th most common cancer-related death in gynecological cancer worldwide. It has been reported that many lncRNAs contribute to oncogenesis although the fundamental mechanisms are basi...

    Authors: Xinghua Shi, Jinzhi Huo, Xingping Gao, Hua Cai and Weipei Zhu

    Citation: Cancer Cell International 2020 20:358

    Content type: Primary research

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  6. Increasing researches have reported that circular RNA UBAP2 (circUBAP2) may be a potential prognosis biomarker and participate in the development of several cancers; however, the role of circUBAP2 in cervical ...

    Authors: Lingli Meng, Xiupeng Jia, Wenying Yu, Chunnian Wang, Jie Chen and Fenglei Liu

    Citation: Cancer Cell International 2020 20:357

    Content type: Primary research

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  7. EPB41L1 gene (erythrocyte membrane protein band 4.1 like 1) encodes the protein 4.1N, a member of 4.1 family, playing a vital role in cell adhesion and migration, which is associated with the malignant progres...

    Authors: Taotao Liang, Siyao Sang, Qi Shao, Chen Chen, Zhichao Deng, Ting Wang and Qiaozhen Kang

    Citation: Cancer Cell International 2020 20:356

    Content type: Primary research

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  8. Esophageal cancer is one of the most common cancers worldwide with poor prognosis and high mortality. The transcription factor SNAI1, encoding Snail1, is important for metastatic progression in esophageal cancer ...

    Authors: Gang Li, Hong-wei Qi, He-gui Dong, Ping Bai, Ming Sun and Hai-yan Liu

    Citation: Cancer Cell International 2020 20:355

    Content type: Primary research

    Published on:

  9. Cervical cancer (CC) is one of the most common female malignancies over the world. Microtubule-associated protein 7 (MAP7) belongs to the family of microtubule-associated proteins (MAPs) which involve in micro...

    Authors: Ning Tang, Dan Lyu, Jian-Fang Chang, Zhi-Tao Liu, Yan Zhang and Hai-Ping Liu

    Citation: Cancer Cell International 2020 20:354

    Content type: Primary research

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  10. anaplastic thyroid cancer (ATC) is one of the most lethal and aggressive cancers. Evidence has shown that the tumorigenesis of ATC is a multistep process involving the accumulation of genetic and epigenetic ch...

    Authors: Hilda Samimi, Sayed Mahmoud Sajjadi-Jazi, Soroush Seifirad, Rasha Atlasi, Habibollah Mahmoodzadeh, Mohammad Ali Faghihi and Vahid Haghpanah

    Citation: Cancer Cell International 2020 20:352

    Content type: Review

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  11. Gastric cancer is a serious malignant tumor associated with aberrant circular RNAs (circRNAs) expression. In this study, we aim to investigate the role and the underlying mechanism of circ_0000190, a circRNA i...

    Authors: Gui-Jun Wang, Tian-Yu Yu, Yan-Rong Li, Yang-Jun Liu and Bei-Bei Deng

    Citation: Cancer Cell International 2020 20:351

    Content type: Primary research

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  12. Genetic and epigenetic alterations have been indicated to be closely correlated with the carcinogenesis, DNA methylation is one of most frequently occurring molecular behavior that take place early during this...

    Authors: Qixin Lian, Bo Wang, Lijun Fan, Junqiang Sun, Guilai Wang and Jidong Zhang

    Citation: Cancer Cell International 2020 20:349

    Content type: Primary research

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  13. Long non-coding RNAs (lncRNAs) are a class of endogenous non-coding RNAs of longer than 200 bp that play crucial roles in cancer biology. Here, we assessed the tumorigenic properties of a long noncoding RNA, M...

    Authors: Zhi Zhou, Shan Zhang and Yaqiong Xiong

    Citation: Cancer Cell International 2020 20:348

    Content type: Primary research

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  14. Human AlkB homolog H5 (ALKBH5) is a primary m6A demethylase, which is dysregulated and acts as a biological and pharmacological role in human cancers or non-cancers. ALKBH5 plays a dual role in various cancers...

    Authors: Jinyan Wang, Jinqiu Wang, Quan Gu, Yajun Ma, Yan Yang, Jing Zhu and Quan’an Zhang

    Citation: Cancer Cell International 2020 20:347

    Content type: Review

    Published on:

  15. Colorectal cancer (CRC) is one of the most common digestive malignant tumors in the world. Ubiquitin-specific peptidase 18 (USP18) plays a regulatory role in tumorigenesis, and abnormal expression of Snail1 is...

    Authors: Fakun Huang, Chengying Zheng, Longkai Huang, Changqing Lin and Jiaxing Wang

    Citation: Cancer Cell International 2020 20:346

    Content type: Primary research

    Published on:

  16. Meningiomas are the second most common primary tumors of the central nervous system. However, there is a paucity of data on meningioma biology due to the lack of suitable preclinical in vitro and in vivo model...

    Authors: Eunhye Kim, Mirae Kim, Kyungha So, Young Seok Park, Chang Gok Woo and Sang-Hwan Hyun

    Citation: Cancer Cell International 2020 20:345

    Content type: Primary research

    Published on:

  17. Concurrent chemoradiotherapy is the common first-line treatment for patients with advanced cervical cancer. However, radioresistance remains a major clinical challenge, which results in recurrence and poor sur...

    Authors: Shan-Shan Yang, De-Yang Yu, Yu-Ting Du, Le Wang, Lina Gu, Yun-Yan Zhang and Min Xiao

    Citation: Cancer Cell International 2020 20:344

    Content type: Primary research

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  18. Long non-coding RNAs (lncRNAs) play significant roles in tumorigenesis and can contribute to identification of novel therapeutic targets for cancers. This paper was aimed at exploring the role of CTBP1 diverge...

    Authors: Shanshan Yang, Feng Shi, Yuting Du, Zhao Wang, Yue Feng, Jiayu Song, Yunduo Liu and Min Xiao

    Citation: Cancer Cell International 2020 20:343

    Content type: Primary research

    Published on:

  19. Aberrant methylation and miRNA-target-gene regulation function as important mechanisms for gene inactivation in colon carcinogenesis. Although a serious of molecular events (such as aberrant alterations of gen...

    Authors: Jiaxin Liu, Zhao Liu, Xiaozhi Zhang, Yanli Yan, Shuai Shao, Demao Yao and Tuotuo Gong

    Citation: Cancer Cell International 2020 20:342

    Content type: Primary research

    Published on:

  20. Cervical cancer (CC) is the second leading cause of cancer deaths in women worldwide, still lacking effective biomarkers and therapies for diagnosis and treatment. CircRNAs are a class of endogenous RNAs that ...

    Authors: Shuaisai Zhang, Zhengli Chen, Jinxue Sun, Na An and Qinghua Xi

    Citation: Cancer Cell International 2020 20:287

    Content type: Primary research

    Published on:

  21. As one of the most lethal cancers, pancreatic cancer has been characterized by abundant supportive tumor-stromal cell microenvironment. Although the advent of tumor-targeted immune checkpoint blockers has brou...

    Authors: Tong Li, Qiaofei Liu, Ronghua Zhang, Quan Liao and Yupei Zhao

    Citation: Cancer Cell International 2020 20:341

    Content type: Primary research

    Published on:

    The Correction to this article has been published in Cancer Cell International 2020 20:397

  22. Long non-coding RNAs (lncRNAs) have been certified to be involved in the occurrence and growth of diverse cancers, including CRC. The purpose of the research was to explore the effects of lncRNA KCNQ1 overlapp...

    Authors: Xing Liu, Yexiang Zhang, Yan Wang, Chao Bian and Fengji Wang

    Citation: Cancer Cell International 2020 20:340

    Content type: Primary research

    Published on:

  23. GATA binding protein 3 (GATA3) and miR-29b are related to colorectal cancer (CRC). The current study explored the regulatory relationship between GATA3 and miR-29b, and the mechanism of the two in the drug res...

    Authors: Wei Wang, Mei Wang, Jing Xu, Fei Long and Xianbao Zhan

    Citation: Cancer Cell International 2020 20:339

    Content type: Primary research

    Published on:

  24. Cell autophagy has been proposed to be involved in drug resistance therapy. However, how the long non-coding RNA (lncRNA) reduces risks of drug resistance in renal cancer (RC) cells needs a thorough inquiry. T...

    Authors: Dechao Li, Changfu Li, Yongsheng Chen, Lichen Teng, Yan Cao, Wentao Wang, Hongxin Pan, Yongpeng Xu and Dan Yang

    Citation: Cancer Cell International 2020 20:338

    Content type: Primary research

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  25. Glioblastoma multiforme (GBM) is the most common and lethal type of primary brain tumor. More than half of GBMs contain mutation(s) of PTEN/PI3K/AKT, making inhibitors targeting the PI3K pathway very attractiv...

    Authors: Zhen Chen, Chao Chen, Tingting Zhou, Chao Duan, Qianqian Wang, Xiaohui Zhou, Xia Zhang, Fangrong Wu, Yunfen Hua and Fan Lin

    Citation: Cancer Cell International 2020 20:337

    Content type: Primary research

    Published on:

  26. Accumulating data suggested that circular RNAs (circRNAs) played important roles in the development of human cancer. However, the potential mechanism of circRNAs in ovarian cancer remains unclear.

    Authors: Chunli Lin, Xiaofeng Xu, Qiumin Yang, Lu Liang and Shulin Qiao

    Citation: Cancer Cell International 2020 20:336

    Content type: Primary research

    Published on:

  27. Antisense non-coding RNA in the INK4 locus (ANRIL) is of great importance in cell biological behaviors, and ANRIL functions in many kinds of cancers including leukemia. However, the mechanism of ANRIL in the p...

    Authors: Gang Li, Lan Gao, Jing Zhao, Dejun Liu, Hui Li and Min Hu

    Citation: Cancer Cell International 2020 20:335

    Content type: Primary research

    Published on:

  28. One of the main reasons for the failure of prostate cancer (PCa) treatment is the generation of chemoresistance. Circular RNA hsa_circ_0000735 (hsa_circ_0000735) is connected with the progression of cancer. Ne...

    Authors: Yisheng Gao, Jie Liu, Jing Huan and Fengyuan Che

    Citation: Cancer Cell International 2020 20:334

    Content type: Primary research

    Published on:

  29. Cervical cancer (CC) is a malignant tumor found in the lowermost part of the womb. Evolving studies on CC have reported that circRNA plays a crucial role in CC progression. In this study, we investigated the m...

    Authors: Xinhua Qu, Liumei Zhu, Linlin Song and Shaohua Liu

    Citation: Cancer Cell International 2020 20:333

    Content type: Primary research

    Published on:

  30. Fatty acid synthase (FASN) is highly expressed in various types of cancer and has an important role in carcinogenesis and metastasis. To clarify the mechanisms of FASN in liver cancer invasion and metastasis, ...

    Authors: Juan Huang, Yao Tang, Xiaoqin Zou, Yi Lu, Sha She, Wenyue Zhang, Hong Ren, Yixuan Yang and Huaidong Hu

    Citation: Cancer Cell International 2020 20:332

    Content type: Primary research

    Published on:

  31. Although major driver gene have been identified, the complex molecular heterogeneity of renal cell cancer (RCC) remains unclear. Therefore, more relevant genes need to be identified to explain the pathogenesis...

    Authors: Yeda Chen, Di Gu, Yaoan Wen, Shuxin Yang, Xiaolu Duan, Yongchang Lai, Jianan Yang, Daozhang Yuan, Aisha Khan, Wenqi Wu and Guohua Zeng

    Citation: Cancer Cell International 2020 20:331

    Content type: Primary research

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  32. The incidence of lung squamous cell carcinoma (LUSC) increased substantially in recent years. Systematical investigation of the immunogenomic pattern is critical to improve the prognosis of LUSC.

    Authors: Jianguo Zhang, Jianzhong Zhang, Cheng Yuan, Yuan Luo, Yangyi Li, Panpan Dai, Wenjie Sun, Nannan Zhang, Jiangbo Ren, Junhong Zhang, Yan Gong and Conghua Xie

    Citation: Cancer Cell International 2020 20:330

    Content type: Primary research

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  33. Endometrial cancer (EnCa) ranks fourth in menace within women’s malignant tumors. Large numbers of studies have proven that functional genes can change the process of tumors by regulating the cell cycle, there...

    Authors: Jinhui Liu, Jie Mei, Siyue Li, Zhipeng Wu and Yan Zhang

    Citation: Cancer Cell International 2020 20:329

    Content type: Primary research

    Published on:

  34. Despite decades of therapeutic trials, effective diagnosis, many drugs available and numerous studies on breast cancer, it remains the deadliest cancer in women. In order to choose the most appropriate treatme...

    Authors: Augustin Le Naour, Yvonne Koffi, Mariane Diab, Delphine Le Guennec, Stéphanie Rougé, Sahar Aldekwer, Nicolas Goncalves-Mendes, Jérémie Talvas, Marie-Chantal Farges, Florence Caldefie-Chezet, Marie-Paule Vasson and Adrien Rossary

    Citation: Cancer Cell International 2020 20:328

    Content type: Primary research

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  35. Long non-coding RNAs (lncRNAs) has been extensively reported play important roles in regulating the development and progression of cancers, including Glioblastoma (GBM). LINC01426 is a novel lncRNA that has be...

    Authors: Jingwei Cao, Zhanbin Tang and Zhiqiang Su

    Citation: Cancer Cell International 2020 20:327

    Content type: Primary research

    Published on:

  36. The outlook for new therapeutic approaches is pivotal to ameliorate the deterioration caused by the abrogated Wnt signaling. Long non-coding RNAs (lncRNAs) are tiny molecules that have begun emerging as vital mol...

    Authors: Zeeshan Javed, Khushbukhat Khan, Haleema Sadia, Shahid Raza, Bahare Salehi, Javad Sharifi-Rad and William C. Cho

    Citation: Cancer Cell International 2020 20:326

    Content type: Review

    Published on:

  37. Methylation of histone 3 at lysine 9 (H3K9) and DNA methylation are epigenetic marks correlated with genes silencing. The tumor microenvironment significantly influences therapeutic responses and clinical outc...

    Authors: Li Zhang, Sijuan Tian, Minyi Zhao, Ting Yang, Shimin Quan, Qing Yang, Lihua Song and Xiaofeng Yang

    Citation: Cancer Cell International 2020 20:325

    Content type: Primary research

    Published on:

  38. Cholangiocarcinoma (CCA) is a mortal cancer with high mortality, whereas the function and mechanism of occurrence and progression of CCA are still mysterious. Long non-coding RNAs (lncRNAs) could function as i...

    Authors: Lining Huang, Xingming Jiang, Zhenglong Li, Jinglin Li, Xuan Lin, Zengtao Hu and Yunfu Cui

    Citation: Cancer Cell International 2020 20:324

    Content type: Primary research

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  39. Prostate cancer (PCa) is a malignant heterogeneous tumor that threatens men’s health. Long non-coding RNA activated by DNA damage (NORAD) and microRNA-495-3p (miR-495-3p) have been revealed to be concerned wit...

    Authors: Fengling Chen, Ling Liu and Shuya Wang

    Citation: Cancer Cell International 2020 20:323

    Content type: Primary research

    Published on:

  40. Long non-coding RNAs (lncRNAs) have been defined as vital regulators in the progression of human cancers, including colorectal cancer (CRC). Long intergenic non-protein coding RNA 667 (LINC00667) is a tumor pr...

    Authors: Juan Yu, Furang Wang, Jun Zhang, Jing Li, Xiaoguang Chen and Guangsen Han

    Citation: Cancer Cell International 2020 20:322

    Content type: Primary research

    Published on:

  41. Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) play vital roles in human cancers. Nevertheless, the effects of lncRNAs and miRNAs on breast cancer (BC) remain to be further investigated. This study was d...

    Authors: Shaoqiang Cheng, Bingshu Xia, Hongbin Li, Yuying Li, Xinxin Lv, Yue Zhang and Yuanxi Huang

    Citation: Cancer Cell International 2020 20:321

    Content type: Primary research

    Published on:

  42. Breast cancer (BC) is a common malignancy worldwide. It has been reported that long non-coding RNA (lncRNA) HOX transcript antisense RNA (HOTAIR) is abnormally expressed in BC. However, the role of HOTAIR in t...

    Authors: Yuanyuan Wang, Guoliang Gong, Jingyun Xu, Yuanxin Zhang, Shenggui Wu and Shaohong Wang

    Citation: Cancer Cell International 2020 20:320

    Content type: Primary research

    Published on:

  43. Long noncoding RNA (lncRNA) is generally identified as competing endogenous RNA (ceRNA) that plays a vital role in the pathogenesis of kidney renal clear cell carcinoma (KIRC), the most common subtype of renal...

    Authors: Di Zhang, Song Zeng and Xiaopeng Hu

    Citation: Cancer Cell International 2020 20:319

    Content type: Primary research

    Published on:

  44. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Yang Hu, Hong Xie, Yankun Liu, Weiying Liu, Min Liu and Hua Tang

    Citation: Cancer Cell International 2020 20:318

    Content type: Correction

    Published on:

    The original article was published in Cancer Cell International 2017 17:36

  45. Papillary renal cell carcinoma (pRCC) accounting for near 20% of renal cell carcinoma is the second most common histological subtype. MiRNAs have been demonstrated to played significant roles on predicting pro...

    Authors: Ge Li, Haifan Yang, Yong Cheng, Xin Zhao, Xu Li and Rui Jiang

    Citation: Cancer Cell International 2020 20:317

    Content type: Primary research

    Published on:

  46. Accumulating amount of evidence has highlighted the important roles of long non-coding RNAs (lncRNAs) acting as competing endogenous RNAs (ceRNAs) in tumor pathogenesis. However, the roles of long non coding R...

    Authors: Zhichen Kang, Lixin Guo, Zhuo Zhu and Rongfeng Qu

    Citation: Cancer Cell International 2020 20:315

    Content type: Primary research

    Published on:

  47. The aim of this study was to investigate the association between telomerase reverse transcriptase (TERT) gene polymorphisms and acute myeloid leukemia (AML) susceptibility in a Chinese Han population.

    Authors: Yong Tong, Yinzhou Xiang, Bao Li, Shijie Bao, Ying Zhou, Wen Yuan, Yu Ling, Dan Hao, Huamin Zhu and Zhiqiang Sun

    Citation: Cancer Cell International 2020 20:313

    Content type: Primary research

    Published on:

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