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  1. Emerging studies have disclosed long non-coding RNAs (lncRNAs) as pivotal modulators in the progression of prostate cancer (PCa). Current research planned to figure out the involvement of lncRNA nicotinamide n...

    Authors: Changlei Yao, Xianghua Cheng, Xiuquan Guo, Xulou Lu, Fan Bu and Yanfen Xu
    Citation: Cancer Cell International 2020 20:463
    Content type: Primary research Published on:

  2. Several studies were conducted to explore the prognostic value of modified Glasgow Prognostic Score (mGPS) in pancreatic cancer, which reported contradictory results. The purpose of this meta-analysis was to s...

    Authors: Huan Zhang, Dianyun Ren, Xin Jin and Heshui Wu
    Citation: Cancer Cell International 2020 20:462
    Content type: Primary research Published on:

  3. Large-scale initiatives like The Cancer Genome Atlas (TCGA) performed genomics studies on predominantly Caucasian kidney cancer. In this study, we aimed to investigate genomics of Chinese clear cell renal cell...

    Authors: Qiang Zhao, Jia Xue, Baoan Hong, Wubin Qian, Tiezhu Liu, Bin Fan, Jie Cai, Yongpeng Ji, Jia Liu, Yong Yang, Qixiang Li, Sheng Guo and Ning Zhang
    Citation: Cancer Cell International 2020 20:461
    Content type: Primary research Published on:

  4. LncRNAs act as functional regulators in tumor progression through interacting with various signaling pathways in multiple types of cancer. However, the effect of LINC02418 on colorectal cancer (CRC) progressio...

    Authors: Jun Tian, Peng Cui, Yifei Li, Xuequan Yao, Xiaoyu Wu, Zhirong Wang and Chunsheng Li
    Citation: Cancer Cell International 2020 20:460
    Content type: Primary research Published on:

  5. Centromere protein F (CENPF) is a key component of the kinetochore complex involved in mitosis, cell differentiation and cellular response to stresses. However, the alteration of CENPF in response to endoplasm...

    Authors: Tao Shen, Yan Li, Shuang Liang and Zhiguang Chen
    Citation: Cancer Cell International 2020 20:459
    Content type: Primary research Published on:

  6. Radiotherapy is one of the main treatments for pancreatic cancer, but radiation resistance limits its clinical application. As a result, novel therapeutic agents to improve radiosensitivity are urgently needed...

    Authors: Biqin Tan, Rong Dong, Bo Zhang, Youyou Yan, Qingyu Li, Fei Wang and Nengming Lin
    Citation: Cancer Cell International 2020 20:458
    Content type: Primary research Published on:

  7. Pancreatic cancer is one of the main causes of tumor-related deaths worldwide because of its low morbidity but extremely high mortality, and is therefore colloquially known as the “king of cancer.” Sudden onse...

    Authors: Yizhi Wang, Li Zhou, Jun Lu, Bolun Jiang, Chengxi Liu, Junchao Guo and Gary Guishan Xiao
    Citation: Cancer Cell International 2020 20:457
    Content type: Review Published on:

  8. Cancer immunotherapy has been emerged as a promising strategy for treatment of a broad spectrum of malignancies ranging from hematological to solid tumors. One of the principal approaches of cancer immunothera...

    Authors: Seyed Mohammad Miri, Elham Tafsiri, William Chi Shing Cho and Amir Ghaemi
    Citation: Cancer Cell International 2020 20:456
    Content type: Review Published on:

    The Correction to this article has been published in Cancer Cell International 2020 20:521

  9. Some studies have investigated the prognostic value exhibited by the Prognostic Nutritional Index (PNI) in patients suffering diffuse large B-cell lymphoma (DLBCL), but varying results were obtained. In order ...

    Authors: Chunyan Luan, Fei Wang, Ning Wei and Baoan Chen
    Citation: Cancer Cell International 2020 20:455
    Content type: Research Article Published on:

  10. Triple-negative breast cancer (TNBC) is a clinically aggressive subtype of breast cancer with a bad prognosis. Chemotherapy is still the standard of care for TNBC treatment. Circular RNAs (CircRNAs) have been ...

    Authors: Dongwei Dou, Xiaoyang Ren, Mingli Han, Xiaodong Xu, Xin Ge, Yuanting Gu, Xinxing Wang and Song Zhao
    Citation: Cancer Cell International 2020 20:454
    Content type: Primary research Published on:

  11. It has been well documented that long non-coding RNAs (lncRNAs) regulate numerous characteristics of cancer, including proliferation, migration, metastasis, apoptosis, and even metabolism. LncRNA BCYRN1 (BCYRN...

    Authors: Liu Yang, Yinan Zhang, Jun Bao and Ji-Feng Feng
    Citation: Cancer Cell International 2020 20:453
    Content type: Primary research Published on:

  12. Drug resistance to 5-fluorouracil (5-FU) and recurrence after chemotherapy in colorectal cancer remain a challenge to be resolved for the improvement of patient outcomes. It is recognized that a variety of sec...

    Authors: Siyuan Chang, Jing Huang, Huan Niu, Jing Wang, Yang Si, Zhigang Bai, Shan Cheng and Wei Ding
    Citation: Cancer Cell International 2020 20:452
    Content type: Primary research Published on:

  13. Kejinyan decoction, as an experienced formula of Zhou Zhongying (the Master of Traditional Chinese Medicine) has been widely used in clinic for lung cancer treatment in China, while the anti-lung cancer mechan...

    Authors: Meijuan Chen, Cheng Hu, Qian Gao, Liqiu Li, Ziyu Cheng, Qirui Li, Zhihui Li, Zhaohui Wang, Zejia Mao, Weiqian Tian and Xu Zhang
    Citation: Cancer Cell International 2020 20:451
    Content type: Primary research Published on:

  14. Hexokinase domain component 1 (HKDC1) plays an oncogenic role in certain types of cancer, such as lymphoma, liver cancer, and breast cancer. Previous bioinformatics study revealed that HKDC1 was significantly ...

    Authors: Xinyu Wang, Bowen Shi, Yue Zhao, Qijue Lu, Xiang Fei, Chaojing Lu, Chunguang Li and Hezhong Chen
    Citation: Cancer Cell International 2020 20:450
    Content type: Primary research Published on:

  17. Epithelial ovarian cancer (EOC), a subclass of ovarian cancer (OC), is usually diagnosed at advanced stages due to the lack of effective screening means. Mounting reports have disclosed the vitally important r...

    Authors: Deying Wang, Yulan Cui, Aili Xu, Lin Zhao and Peiling Li
    Citation: Cancer Cell International 2020 20:447
    Content type: Primary research Published on:

  18. To analyze the clinical efficacy of intraoperative radiotherapy (IORT) after breast-conserving surgery (BCS) in patients with early-stage breast cancer (BC), and to investigate the relationship between its inf...

    Authors: Lin Wang, Minmin Zhu, Yuelong Cui, Xudong Zhang and Guowen Li
    Citation: Cancer Cell International 2020 20:446
    Content type: Primary research Published on:

  19. Runt related transcription factor3 (RUNX3) is considered as a tumor suppressor gene (TSG) that functions through the TGF-β dependent apoptosis. Promoter methylation of the CpG islands of RUNX3 and overexpressi...

    Authors: Asad Ur Rehman, Mohammad Askandar Iqbal, Real Sumayya Abdul Sattar, Snigdha Saikia, Mohammad Kashif, Wasif Mohammad Ali, Subhash Medhi, Sundeep Singh Saluja and Syed Akhtar Husain
    Citation: Cancer Cell International 2020 20:445
    Content type: Primary research Published on:

  20. Urological cancers are responsible for thousands of cancer-related deaths around the world. Despite all developments in therapeutic approaches for cancer therapy, the absence of efficient treatments is a criti...

    Authors: Mohammad Hossein Pourhanifeh, Azam Hosseinzadeh, Kobra Bahrampour Juybari and Saeed Mehrzadi
    Citation: Cancer Cell International 2020 20:444
    Content type: Review Published on:

    The Correction to this article has been published in Cancer Cell International 2020 20:466

  21. The microRNA miR-221-3p has previously been found to be an underlying biomarker of pancreatic cancer. However, the mechanisms of miR-221-3p underlying its role in pancreatic cancer pathogenesis, proliferation ...

    Authors: Xuejiao Wu, Jia Huang, Zilin Yang, Ying Zhu, Yongping Zhang, Jiancheng Wang and Weiyan Yao
    Citation: Cancer Cell International 2020 20:443
    Content type: Primary research Published on:

  22. Acute lymphoblastic leukemia (ALL) is an aggressive hematopoietic malignancy that is most commonly observed in children. Alantolactone (ALT) has been reported to exhibit anti-tumor activity in different types ...

    Authors: Ce Shi, Wenjia Lan, Zhenkun Wang, Dongguang Yang, Jia Wei, Zhiyu Liu, Yueqiu Teng, Mengmeng Gu, Tian Yuan, Fenglin Cao, Jin Zhou and Yang Li
    Citation: Cancer Cell International 2020 20:442
    Content type: Primary research Published on:

  24. It has reported that long non-coding RNAs (lncRNAs) exerted regulatory functions by targeting specific genes through a competing endogenous RNA (ceRNA) pathway. LncRNA OIP5-AS1 has been identified as a tumor-e...

    Authors: Yu Wang, Lei Dou, Yun Qin, Huiyuan Yang and Peng Yan
    Citation: Cancer Cell International 2020 20:440
    Content type: Primary research Published on:

  25. KLF5 is a member of the Kruppel-like factor, subfamily of zinc finger proteins that are involved in cancers. KLF5 functions as a transcription factor and regulates the diverse protein-coding genes (PCGs) in color...

    Authors: Qi Liao, Linbo Chen, Ning Zhang, Yang Xi, Shiyun Hu, Derry Minyao Ng, Fatma Yislam Hadi Ahmed, Guofang Zhao, Xiaoxiang Fan, Yangyang Xie, Xiaoyu Dai, Yanping Jin, Jiaxin Ge, Changzheng Dong, Xinjun Zhang and Junming Guo
    Citation: Cancer Cell International 2020 20:439
    Content type: Primary research Published on:

  26. Non-small cell lung cancer (NSCLC) is a deadly human malignancy, and previous studies support the contribution of microRNAs (miRNAs) to cancer assessment. It has been reported that miR-1231 can be used as a bi...

    Authors: Jing Li, Jialiang Xu, Zhijun Cao, Shouzuo Du and Luyu Zhang
    Citation: Cancer Cell International 2020 20:438
    Content type: Primary research Published on:

  29. Cholangiocarcinoma (CCA) is a rare tumor that arises from cholangiocytes, the epithelial cells of the bile duct. The tumor is characterized by insidious onset, high degree of malignancy, poor prognosis and hig...

    Authors: Mingzhen Bai, Wenkang Fu, Gang Su, Jie Cao, Long Gao, Chongfei Huang, Haidong Ma, Jinduo Zhang, Ping Yue, Bing Bai, Yanyan Lin, Wenbo Meng and Xun Li
    Citation: Cancer Cell International 2020 20:435
    Content type: Review Published on:

  30. The genetic variants of the ARID5B gene have recently been reported to be associated with disease susceptibility and treatment outcome in childhood acute lymphoblastic leukemia (ALL). However, few studies have ex...

    Authors: Minori Tamai, Meixian Huang, Keiko Kagami, Masako Abe, Shinpei Somazu, Tamao Shinohara, Daisuke Harama, Atsushi Watanabe, Koshi Akahane, Kumiko Goi, Kanji Sugita, Hiroaki Goto, Masayoshi Minegishi, Shotaro Iwamoto and Takeshi Inukai
    Citation: Cancer Cell International 2020 20:434
    Content type: Primary research Published on:

  31. Gastric cancer (GC) is one of the high-risk cancers that lacks effective methods for prognosis prediction. Therefore, we searched for immune cells related to the prognosis of GC and studied the role of related...

    Authors: Gang Hu, Ningjie Sun, Jiansong Jiang and Xiansheng Chen
    Citation: Cancer Cell International 2020 20:433
    Content type: Primary research Published on:

  32. Lung adenocarcinoma is metastatic cancer with a high mortality rate. Circular RNAs (circRNAs) are a type of noncoding RNA and play a vital role in cancer progression. However, the expression and function of ci...

    Authors: Yongyong Yan, Jiantian Yang, Janak L. Pathak, Haiyan Wang, Jun Zha, Yongxiang Wei, Haibo Tang and Linhu Ge
    Citation: Cancer Cell International 2020 20:432
    Content type: Primary research Published on:

  33. Circular RNA (circRNA), an novel type of non-coding RNA, could interact with miRNA and protein molecules to regulate the occurrence and progression of hepatocellular carcinoma (HCC). However, little is known a...

    Authors: Yabin Yu, Suyang Han, Meng Li, Yan Song and Fuzhen Qi
    Citation: Cancer Cell International 2020 20:431
    Content type: Primary research Published on:

  34. Growing evidence has revealed the involvement of circular RNAs (circRNAs) in numerous carcinogenesis. However, the role of circRNAs in the cancer biology of colorectal cancer (CRC) remains vague.

    Authors: Jiabin Du, Jianhua Xu, Junxing Chen, Weinan Liu, Pengcheng Wang and Kai Ye
    Citation: Cancer Cell International 2020 20:430
    Content type: Primary research Published on:

  35. Tumor necrosis factor receptor (TNFR)-related factors (TRAFs) are important linker molecules in the tumor necrosis factor superfamily (TNFSF) and the Toll-like/interleukin-1 receptor (TLR/ILR) superfamily. The...

    Authors: Jiaoduan Li, Nian Liu, Ling Tang, Bei Yan, Xiang Chen, Jianglin Zhang and Cong Peng
    Citation: Cancer Cell International 2020 20:429
    Content type: Review Published on:

  36. Glioma is one prevalent malignant tumor originates from the central nervous system. Dysregulation of long non-coding RNAs (lncRNAs) has been found to be a molecular signature behind the pathology of a variety ...

    Authors: Jianguo Qi, Zhengrui Wang, Zhensheng Zhao and Lijun Liu
    Citation: Cancer Cell International 2020 20:428
    Content type: Primary research Published on:

  37. Circular RNAs (circRNAs) are a novel class of noncoding RNAs. Increasing evidence indicates that circRNAs play an important role in the occurrence and development of tumors. However, the role of circRNA hsa_ci...

    Authors: Liang Jing, Junhui Wu, Xiaocheng Tang, Min Ma, Fei Long, Buning Tian and Changwei Lin
    Citation: Cancer Cell International 2020 20:427
    Content type: Primary research Published on:

  38. The methylation of the CpG islands of the LINE-1 promoter is a tight control mechanism on the function of mobile elements. However, simultaneous quantification of promoter methylation and transcription of LINE...

    Authors: Milad Shademan, Khadijeh Zare, Morteza Zahedi, Hooman Mosannen Mozaffari, Hadi Bagheri Hosseini, Kamran Ghaffarzadegan, Ladan Goshayeshi and Hesam Dehghani
    Citation: Cancer Cell International 2020 20:426
    Content type: Primary research Published on:

  39. Dysregulation of fatty acid (FA) metabolism is involved in hepatocellular carcinoma (HCC) development. Non-POU domain-containing octamer binding protein (NONO), known as the component of nuclear paraspeckles, ...

    Authors: Hongda Ding, Junpeng Liu, Caibin Wang and Yang Su
    Citation: Cancer Cell International 2020 20:425
    Content type: Primary research Published on:

  40. Cervical cancer (CC) is the one of most common malignant gynecological tumors, which is characterized with the high mortality and recurrence rate. Previous studies have elucidated the oncogenic role of small n...

    Authors: Jin Liu, Xiaojiao Liu and Rong Li
    Citation: Cancer Cell International 2020 20:424
    Content type: Primary research Published on:

  42. Krüppel-like factor 8 (KLF8), a cancer-promoting factor that regulates critical gene transcription and cellular cancer-related events, has been implicated in tumor development and progression. However, the fun...

    Authors: Ming-Da Wang, Hao Xing, Chao Li, Lei Liang, Han Wu, Xin-Fei Xu, Li-Yang Sun, Meng-Chao Wu, Feng Shen and Tian Yang
    Citation: Cancer Cell International 2020 20:422
    Content type: Primary research Published on:

  43. New screening techniques may affect the optimal approaches for the prevention of cervical cancer. We evaluated the cost-effectiveness and accuracy of alternative screening strategies to provide evidence for ce...

    Authors: Binhua Dong, Lihua Chen, Wenyu Lin, Yingying Su, Xiaodan Mao, Diling Pan, Guanyu Ruan, Huifeng Xue, Yafang Kang and Pengming Sun
    Citation: Cancer Cell International 2020 20:421
    Content type: Primary research Published on:

  44. Most cancer cells exhibit increased glycolysis and use this metabolic pathway cell growth and proliferation. Targeting cancer cells’ metabolism is a promising strategy in inhibiting cancer cell progression. We...

    Authors: Ahmed Ghdhban Al-Ziaydi, Ahmed Majeed Al-Shammari, Mohammed I. Hamzah, Haider Sabah kadhim and Majid Sakhi Jabir
    Citation: Cancer Cell International 2020 20:420
    Content type: Primary research Published on:

  45. Glioblastoma (GBM) is a common and aggressive primary brain tumor, and the prognosis for GBM patients remains poor. This study aimed to identify the key genes associated with the development of GBM and provide...

    Authors: Wei-cheng Lu, Hui Xie, Ce Yuan, Jin-jiang Li, Zhao-yang Li and An-hua Wu
    Citation: Cancer Cell International 2020 20:419
    Content type: Primary research Published on:

  46. Tribbles pseudokinase 3 (TRIB3) protein is a pseudokinase which plays an important role in cellular stress, metabolism, and tumor progression. However, the expression and function of TRIB3 in ovarian cancer is...

    Authors: Shuang Wang, Caixia Wang, Xiao Li, Yuexin Hu, Rui Gou, Qian Guo, Xin Nie, Juanjuan Liu, Liancheng Zhu and Bei Lin
    Citation: Cancer Cell International 2020 20:418
    Content type: Primary research Published on:

  47. Immunocompetent animal models are required to study tumor-host interactions, immunotherapy, and immunotherapeutic combinations, however the currently available immunocompetent lung cancer models have substanti...

    Authors: Kyle Nolan, Gregory Verzosa, Tim Cleaver, Darinee Tippimanchai, Lisa N. DePledge, Xiao-Jing Wang, Christian Young, Anh Le, Robert Doebele, Howard Li and Stephen P. Malkoski
    Citation: Cancer Cell International 2020 20:417
    Content type: Primary research Published on:

  48. This study aimed to investigate the relationship among miR-145-5p, ANGPT2 and the NOD_LIKE_RECEPTOR pathway, thereby revealing the molecular mechanism of these three factors underlying the proliferation, migratio...

    Authors: Kai Zhou, Binbin Song, Ming Wei, Jubo Fang and Yufen Xu
    Citation: Cancer Cell International 2020 20:416
    Content type: Primary research Published on:

  49. Oral squamous cell carcinoma (OSCC) is a common kind of squamous cell carcinoma of the head and neck, which is a threat to public health. Long noncoding RNAs (lncRNAs) are associated with the development of va...

    Authors: Su-Wei Fu, Yan Zhang, Shen Li, Zhi-Yan Shi, Juan Zhao and Qing-Li He
    Citation: Cancer Cell International 2020 20:415
    Content type: Primary research Published on:

  50. Long non-coding RNAs (lncRNAs) play a vital role in the genesis and development of human cancer. LncRNA MIR99AHG has been reported to be upregulated in acute myeloid leukemia (AML); however, its function in ga...

    Authors: Qingyang Meng, Xiangjun Wang, Tongqing Xue, Qiangfang Zhao, Wei Wang and Kun Zhao
    Citation: Cancer Cell International 2020 20:414
    Content type: Primary research Published on:
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Cancer Cell International

ISSN: 1475-2867

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