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  1. Acute myeloid leukemia (AML) with FMS-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) mutation accounts for a large proportion of AML patients and diagnosed with poor prognosis. Although the prog...

    Authors: Xinhua Xiao, Peihong Wang, Weina Zhang, Jiayi Wang, Mansi Cai, Hua Jiang, Yingli Wu and Huizhuang Shan
    Citation: Cancer Cell International 2023 23:302
  2. T lymphoma invasion and metastasis 1 (Tiam1) is a tumor related gene that specifically activates Rho-like GTPases Rac1 and plays a critical role in the progression of various malignancies. Glycolysis plays an ...

    Authors: Ying Liu, Aihua Jin, Xianglan Quan, Xionghu Shen, Houkun Zhou, Xingyu Zhao and Zhenhua Lin
    Citation: Cancer Cell International 2023 23:301
  3. Glucose metabolism is associated with the development of cancers, and m6A RNA methylation regulator-related genes play vital roles in bladder urothelial carcinoma (BLCA). However, the role of m6A-related gluco...

    Authors: Guanwen Zhou, Yi Li, Xiangguo Ren, Guoliang Qin, Zhaocun Zhang, Haifeng Zhao, Lijian Gao and Xianzhou Jiang
    Citation: Cancer Cell International 2023 23:300
  4. Brain metastasis is a common complication among patients with lung cancer, yet the underlying mechanisms remain unclear. In this study, we aimed to investigate the pathogenesis of brain metastasis in lung cancer.

    Authors: Jung Eun Lee, Jihye Park, Eun Ju Kim, Yoon Ho Ko, Soon Auck Hong, Seung Ho Yang and Young-Ho Ahn
    Citation: Cancer Cell International 2023 23:299
  5. Methyltransferase-like 3 (METTL3) is the key subunit of methyltransferase complex responsible for catalyzing N6-methyladenosine (m6A) modification on mRNA, which is the most prevalent post-transcriptional modific...

    Authors: Qingbin Liu, Jingjing Qi, Weiyang Li, Xinchen Tian, Jiaqi Zhang, Fen Liu, Xiulian Lu, Hengchang Zang, Chenqiao Liu, Changlin Ma, Yong Yu and Shulong Jiang
    Citation: Cancer Cell International 2023 23:298
  6. Acute myeloid leukemia (AML) is a clonal malignant disorder which originates from a small number of leukemia-initiating cells or leukemic stem cells (LSCs)—the subpopulation that is also the root cause of rela...

    Authors: Phatchanat Klaihmon, Sudjit Luanpitpong, Xing Kang and Surapol Issaragrisil
    Citation: Cancer Cell International 2023 23:297
  7. Colorectal cancer is a highly prevalent and deadly. The most common metastatic site is the liver. We performed a whole exome sequencing analysis of a series of metachronous colorectal cancer liver metastases (...

    Authors: Lucie Heczko, Viktor Hlaváč, Petr Holý, Pavel Dvořák, Václav Liška, Ondřej Vyčítal, Ondřej Fiala and Pavel Souček
    Citation: Cancer Cell International 2023 23:295
  8. Triple-negative breast Cancer (TNBC) is a highly malignant cancer with unclear pathogenesis. Within the tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) vitally influence tumor onset and prog...

    Authors: Ganggang Wang, Hao Zhang, Xiaowei Shen, Wenzhi Jin, Xiaoliang Wang and Zhijie Zhou
    Citation: Cancer Cell International 2023 23:294
  9. The m6a demethyltransferase ALKBH5 dynamically modulates gene expression and intracellular metabolic molecules by modifying RNA m6a in cancer cells. However, ALKBH5’s function in gastric cancer (GC) has remain...

    Authors: Chunting Chen, Ertao Zhai, Yinan Liu, Yan Qian, Risheng Zhao, Yan Ma, Jianqiu Liu, Zhixin Huang, Jianhui Chen and Shirong Cai
    Citation: Cancer Cell International 2023 23:293
  10. Despite intensive developments of adoptive T cell and NK cell therapies, the efficacy against solid tumors remains elusive. Our study demonstrates that macrophage-based cell therapy could be a potent therapeut...

    Authors: Wen-Han Chuang, Evgeny Pislyagin, Liang-Yu Lin, Ekaterina Menchinskaya, Oleg Chernikov, Valery Kozhemyako, Tatiana Gorpenchenko, Igor Manzhulo, Elena Chaikina, Irina Agafonova, Alexandra Silchenko, Sergey Avilov, Valentin Stonik, Shey-Cherng Tzou, Dmitry Aminin and Yun-Ming Wang
    Citation: Cancer Cell International 2023 23:292
  11. Lack of Schlafen family member 11 (SLFN11) expression has been recently identified as a dominant genomic determinant of response to DNA damaging agents in numerous cancer types. Thus, several strategies aimed ...

    Authors: Christophe Michel Raynaud, Eiman I. Ahmed, Ayesha Jabeen, Apryl Sanchez, Shimaa Sherif, Tatiana C. Carneiro-Lobo, Amany Awad, Dina Awartani, Adviti Naik, Remy Thomas, Julie Decock, Gabriele Zoppoli, Davide Bedongnetti and Wouter R. L. Hendrickx
    Citation: Cancer Cell International 2023 23:291
  12. The aim of this study was to explore the associations of RIPK1 polymorphisms, plasma levels and mRNA expression with susceptibility to epithelial ovarian cancer (EOC) and clinical outcome.

    Authors: Xuedong Wang, Kui Deng, Jing Tao, Juan Zou, Yiting Du and Li Dai
    Citation: Cancer Cell International 2023 23:290
  13. Protein tripartite motif-containing 21 (TRIM21/Ro52), an E3 ubiquitin ligase, is an essential regulator of innate immunity, and its dysregulation is closely associated with the development of autoimmune diseas...

    Authors: Chueh-Hsuan Hsu and Yung-Luen Yu
    Citation: Cancer Cell International 2023 23:289
  14. CircRNAs, a special type of noncoding RNAs characterized by their stable structure and unique abilities to form backsplicing loops, have recently attracted the interest of scientists. These RNAs are abundant t...

    Authors: Chunjie Huang, Pooya Esfani Sarafraz, Parisa Enayati, Elham Mortazavi Mamaghani, Emad Babakhanzadeh and Majid Nazari
    Citation: Cancer Cell International 2023 23:288

    The Correction to this article has been published in Cancer Cell International 2024 24:40

  15. Osteosarcoma (OS) commonly metastasizes to the lung, yet the underlying molecular mechanisms remain poorly understood. Exosomes play a crucial role in tumor migration, including OS lung migration. However, the...

    Authors: Xinyu Chang, Qiuyu Tan, Jinwen Xu, Xu Wu, Ying Wang, Yuan Zhang, Hao Zhang, Haijun Liu and Liang Yan
    Citation: Cancer Cell International 2023 23:287
  16. Chemoresistance is a major clinical challenge that leads to tumor metastasis and poor clinical outcome. The mechanisms underlying gastric cancer resistance to chemotherapy are still unclear.

    Authors: Long-Long Cao, Yu-Kai Wu, Tong-Xin Lin, Mi Lin, Yu-Jing Chen, Ling-Qian Wang, Jia-Bin Wang, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Ru-Hong Tu, Ze-Ning Huang, Ju-Li Lin, Hua-Long Zheng, Jian-Wei Xie, Ping Li…
    Citation: Cancer Cell International 2023 23:286
  17. TSTA3 gene encoding GDP-l-fucose synthase has recently been proved to be closely related to the prognosis of patients with various tumors. However, its role in lung cancer is still unclear. The purpose of this st...

    Authors: Yanlin Guo, Yanlong Hao, Liuyi Shen, Yu Du, Xiaohui Wang, Lvye Gao, Xuefei Feng, Yuanfang Zhai, Zhifei Liu, Enwei Xu, Yue Yang, Yanfeng Xi, Bin Yang and Ling Zhang
    Citation: Cancer Cell International 2023 23:285
  18. Carcinoma of the lung is among the most common types of cancer globally. Concerning its histology, it is categorized as a non-small cell carcinoma (NSCLC) and a small cell cancer (SCLC) subtype. MicroRNAs (miR...

    Authors: Mohammad Saleh Sadeghi, Mohadeseh lotfi, Narges Soltani, Elahe Farmani, Jaime Humberto Ortiz Fernandez, Sheida Akhlaghitehrani, Safaa Hallol Mohammed, Saman Yasamineh, Hesam Ghafouri Kalajahi and Omid Gholizadeh
    Citation: Cancer Cell International 2023 23:284
  19. Hsa_circ_0022383 (circ_0022383) is a newly discovered circRNA. Its functions and relevant molecular mechanisms in tumorigenesis have not been reported. Here we aimed to explore how circ_0022383 regulates the t...

    Authors: Xiaofang Xu, Binbin Song, Qiuliang Zhang, Weibo Qi and Yufen Xu
    Citation: Cancer Cell International 2023 23:282
  20. Chimeric antigen receptor (CAR)-T cell therapy has been used to treat pediatric refractory or relapsed mature B-cell non-Hodgkin lymphoma (r/r MB-NHL) with significantly improved outcomes, but a proportion of ...

    Authors: Yang Li, Yang Liu, Keyan Yang, Ling Jin, Jing Yang, Shuang Huang, Ying Liu, Bo Hu, Rong Liu, Wei Liu, Ansheng Liu, Qinlong Zheng and Yonghong Zhang
    Citation: Cancer Cell International 2023 23:281
  21. Gastrointestinal (GI) cancer is a major health problem worldwide, and current diagnostic and therapeutic approaches are often inadequate. Various metallic nanoparticles (MNPs) have been widely studied for seve...

    Authors: Mohammad Roshani, Arya Rezaian-Isfahni, Mohammad Hassan Lotfalizadeh, Negar Khassafi, Mohammad Hassan Jafari Najaf Abadi and Majid Nejati
    Citation: Cancer Cell International 2023 23:280
  22. Myeloid cells play an essential role in cancer metastasis. The phenotypic diversity of these cells during cancer development has attracted great interest; however, their functional heterogeneity and plasticity...

    Authors: Ansooya A. Bokil, Mathieu Le Boulvais Børkja, Camilla Wolowczyk, Apsana Lamsal, Wenche S. Prestvik, Unni Nonstad, Kristine Pettersen, Sonja B. Andersen, Anna M. Bofin, Geir Bjørkøy, Sjoerd Hak and Miriam S. Giambelluca
    Citation: Cancer Cell International 2023 23:279
  23. Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, with a high mortality and poor survival rate. Abnormal tumor metabolism is considered a hallmark of HCC and is a potential therapeuti...

    Authors: Dongping Li, Xiahui Lin, Jiale Li, Xinyi Liu, Feng Zhang, Wenqing Tang, Si Zhang, Ling Dong and Ruyi Xue
    Citation: Cancer Cell International 2023 23:277
  24. Despite therapeutic advances, the prognosis of pancreatic ductal adenocarcinoma (PDAC) remains extremely poor. Metabolic reprogramming is increasingly recognized as a key contributor to tumor progression and t...

    Authors: Yuchuan Li, Manoj Amrutkar, Anette Vefferstad Finstadsveen, Knut Tomas Dalen, Caroline S. Verbeke and Ivar P. Gladhaug
    Citation: Cancer Cell International 2023 23:276
  25. Cancer-secreted exovesicles are important for cell-to-cell communication by altering cancer-related signalling pathways. Exovesicles-derived miRNAs (exomiRNAs)-target genes can be useful for diagnostic and pro...

    Authors: Antonio Altuna-Coy, Xavier Ruiz-Plazas, Verónica Arreaza-Gil, José Segarra-Tomás and Matilde R. Chacón
    Citation: Cancer Cell International 2023 23:275
  26. Limited benefit population of immunotherapy makes it urgent to select effective biomarkers for screening appropriate treatment population. Herein, we have investigated the predictive values of circulating CD8+ T ...

    Authors: Jiang Liu, Degan Liu, Guangyin Hu, Jingjing Wang, Dadong Chen, Chuanjun Song, Yin Cai, Chentong Zhai and Wenjing Xu
    Citation: Cancer Cell International 2023 23:274
  27. Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease that requires precise diagnosis for effective treatment. However, the diagnostic value of carbohydrate antigen 19 − 9 (CA19-9) is limited. There...

    Authors: Tiandong Li, Junfen Xia, Huan Yun, Guiying Sun, Yajing Shen, Peng Wang, Jianxiang Shi, Keyan Wang, Hongwei Yang and Hua Ye
    Citation: Cancer Cell International 2023 23:273
  28. Helicobacter pylori (H. pylori) infection is a major risk factor for gastric diseases, including gastritis and gastric cancer. Heat shock protein 60 (HSP60) is a chaperone protein involved in various cellular pro...

    Authors: Yujie Li, Hui Cao, Dewen Qiu, Nan Wang, Yan Wang, Tingting Wen, Jianjun Wang and Hong Zhu
    Citation: Cancer Cell International 2023 23:272
  29. Recent developments in sequencing technology and analytical approaches have allowed researchers to show that the healthy gut microbiome is very varied and capable of performing a wide range of tasks. The impor...

    Authors: Fatemehsadat Mousavinasab, Ronika karimi, Sima Taheri, Fatemeh Ahmadvand, Saameh Sanaaee, Sajad Najafi, Masood Soltani Halvaii, Alireza Haghgoo, Marzieh Zamany, Jamal Majidpoor, Mina Khosravifar, Mohammad Baniasadi, Mehrdad Talebi, Abolfazl Movafagh, Seyed Mohsen Aghaei-Zarch, Nastaran Khorram…
    Citation: Cancer Cell International 2023 23:271
  30. Prostate cancer (PCa) is the second leading cause of cancer-related deaths among men worldwide. Immunotherapy is an emerging treatment modality for cancers that harnesses the immune system’s ability to elimina...

    Authors: Parisa Bakhshi, Maryam Nourizadeh, Laleh Sharifi, Mohammad M. Farajollahi and Monireh Mohsenzadegan
    Citation: Cancer Cell International 2023 23:270
  31. The incidence and prevalence of nonalcoholic fatty liver disease related hepatocellular carcinoma (NAFLD-HCC) are rapidly increasing worldwide. This study aimed to identify biomarker genes for prognostic predi...

    Authors: Yuting Song, Ying Wang, Xin Geng, Xianming Wang, Huisi He, Youwen Qian, Yaping Dong, Zhecai Fan, Shuzhen Chen, Wen Wen and Hongyang Wang
    Citation: Cancer Cell International 2023 23:269
  32. Colorectal cancer (CRC) is one of the foremost causes of cancer-related deaths. Lately, a close connection between the course of CRC and the intestinal microbiota has been revealed. Vitamin K2 (VK2) is a bacteria...

    Authors: Joanna Smajdor, Katarzyna Jedlińska, Radosław Porada, Anna Górska-Ratusznik, Aleksandra Policht, Małgorzata Śróttek, Grażyna Więcek, Bogusław Baś and Magdalena Strus
    Citation: Cancer Cell International 2023 23:268
  33. Disulfidptosis and Ferroptosis are two novel forms of cell death. Although their mechanisms differ, research has shown that there is a relationship between the two. Investigating the connection between these t...

    Authors: Xiaoqing Ma, Zilin Deng, Zhen Li, Ting Ma, Guiqing Li, Cuijia Zhang, Wentao Zhang and Jin Chang
    Citation: Cancer Cell International 2023 23:267
  34. The hypoxia-responsive long non-coding RNA, RP11-367G18.1, has recently been reported to induce histone 4 lysine 16 acetylation (H4K16Ac) through its variant 2; however, the underlying molecular mechanism remains...

    Authors: Pei-Hua Peng, Ji-Lin Chen, Heng-Hsiung Wu, Wen-Hao Yang, Li-Jie Lin, Joseph Chieh-Yu Lai, Jeng-Shou Chang, Jia-Ling Syu, Han-Tsang Wu, Fei-Ting Hsu, Wei-Chung Cheng and Kai-Wen Hsu
    Citation: Cancer Cell International 2023 23:266
  35. V-domain immunoglobulin suppressor of T cell activation (VISTA) is a novel negative checkpoint receptor (NCR) primarily involved in maintaining immune tolerance. It has a role in the pathogenesis of autoimmune...

    Authors: Najibeh Shekari, Dariush Shanehbandi, Tohid Kazemi, Habib Zarredar, Behzad Baradaran and Seyed Amir Jalali
    Citation: Cancer Cell International 2023 23:265
  36. "Inflammatory bowel disease" (IBD) is a chronic, relapsing inflammatory disease of the intestinal tract that typically begins at a young age and might transit to colorectal cancer (CRC). In this manuscript, we...

    Authors: Zeinab Deris Zayeri, Abazar Parsi, Saeid Shahrabi, Masoud Kargar, Nader Davari and Najmaldin Saki
    Citation: Cancer Cell International 2023 23:264
  37. Gamma-butyrobetaine hydroxylase 1 antisense RNA 1 (BBOX1-AS1), located on human chromosome 11 p14, emerges as a critical player in tumorigenesis with diverse oncogenic effects. Aberrant expression of BBOX1-AS1...

    Authors: Juan Hu, Jipeng Liu, Siwei Zhou and Hongliang Luo
    Citation: Cancer Cell International 2023 23:263
  38. Gene status has become the focus of prognosis prediction. Furthermore, deep learning has frequently been implemented in medical imaging to diagnose, prognosticate, and evaluate treatment responses in patients ...

    Authors: Jie Peng, Lushan Xiao, Hongbo Zhu, Lijie Han and Honglian Ma
    Citation: Cancer Cell International 2023 23:262
  39. There is a growing interest to understand the role and mechanism of action of microRNAs (miRNAs) in cancer. The miRNAs are defined as short non-coding RNAs (18-22nt) that regulate fundamental cellular processe...

    Authors: Ali Ameri, Hani Moslem Ahmed, Renzon Daniel Cosme Pecho, Hesamoddin Arabnozari, Hoda Sarabadani, Romina Esbati, Seyedsaber Mirabdali and Omid Yazdani
    Citation: Cancer Cell International 2023 23:261
  40. Circular RNA RHOT1 (circRHOT1) plays crucial roles in tumorigenesis by competing with microRNAs. It is largely abundant in tumor cell-derived exosomes. Meanwhile, cancer-derived exosomes participate in diverse...

    Authors: Weihua Jiang, YinPing Yu, Jianghua Ou, Yongtao Li and Ning Zhu
    Citation: Cancer Cell International 2023 23:260
  41. Disulfidptosis and the disulfidptosis-related gene SLC7A11 have recently attracted significant attention for their role in tumorigenesis and tumour management. However, its association with adrenocortical carc...

    Authors: Tonghu Liu, Yilin Ren, Qixin Wang, Yu Wang, Zhiyuan Li, Weibo Sun, Dandan Fan, Yongkun Luan, Yukui Gao and Zechen Yan
    Citation: Cancer Cell International 2023 23:259
  42. Metastasis is still a major cause of poor pathological outcome and prognosis in esophageal squamous cell carcinoma (ESCC) patients. NUAK1 has been reported highly expressed in many human cancers and is associa...

    Authors: Huiru Yang, Zhen Wei, Yifan Song, Kexin Du, Nannan Yin, Hong Lu, Bingbing Li, Lili Hou, Panfei Xing, Liang Chen, Chaojie Wang and Songqiang Xie
    Citation: Cancer Cell International 2023 23:258
  43. Cancer cells promote glycolysis, which supports rapid cell growth and proliferation. Phosphofructokinase-fructose bisphosphatases (PFKFBs), a family of bidirectional glycolytic enzymes, play key roles in the r...

    Authors: Kai-Fang Hu, Chih-Wen Shu, Cheng-Hsin Lee, Ching-Jiunn Tseng, Yu-Hsiang Chou and Pei-Feng Liu
    Citation: Cancer Cell International 2023 23:257
  44. Gastrointestinal stromal tumors (GIST) represent a significant clinical challenge due to their metastatic potential and limited treatment options. Raf kinase inhibitor protein (RKIP), a suppressor of the MAPK ...

    Authors: Nathália Cristina Campanella, Izabela Natalia Faria Gomes, Ana Laura Vieira Alves, Leticia Ferro Leal, Adriane Feijó Evangelista, Marcela Nunes Rosa, Matias Eliseo Melendez, Viviane Aline Oliveira Silva, Richard Lucas Konichi Dias, Lucas Faria Abrahão-Machado, Iara Santana, Olga Martinho, Denise Peixoto Guimarães, Vitor Marcel Faça and Rui Manuel Reis
    Citation: Cancer Cell International 2023 23:256
  45. THBS2, a member of the extracellular matrix glycoprotein family, can effectively inhibit tumour growth and angiogenesis. This study aimed to investigate the biological role of THBS2 in various types of cancers...

    Authors: Ye Liu, Chunhui Jiang, Chunjie Xu and Lei Gu
    Citation: Cancer Cell International 2023 23:253

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