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  1. Authors: P Wimberger, A Burges, V Gorbounova, H Sommer, B Schmalfeldt, J Pfisterer, M Lichinitser, A Makhson, M Ströhlein, W Eiermann, M Biakhov, V Moiseenko, A du Bois and R Kimmig

    Citation: Cancer Cell International 2004 4(Suppl 1):S3

    Content type: Oral presentation

    Published on:

    This article is part of a Supplement: Volume 4 Supplement 1

  2. Malignant peripheral nerve sheath tumors (MPNSTs) are neoplasms leading to death in most cases. Patients with Neurofibromatosis type 1 have an increased risk of developing this malignancy. The metabolites of t...

    Authors: Silke Frahm, Andreas Kurtz, Lan Kluwe, Faris Farassati, Reinhard E Friedrich and Victor F Mautner

    Citation: Cancer Cell International 2004 4:4

    Content type: Primary research

    Published on:

  3. Flow cytometry, DNA fragmentation, ion ratiomateric analysis and NMR peaks characterized drug chemosensitivity of antineoplastic drugs. Hypotheses were: 1. The chemosensitive effect of different cancer cell li...

    Authors: Rakesh Sharma and Richard Kline

    Citation: Cancer Cell International 2004 4:3

    Content type: Primary research

    Published on:

  4. Accumulating evidences suggest that Hsp 70, the inducible component of Hsp70 family, might release from a living cell. Here we show that a pharmacological inhibitor of phospholipase C activity U73122 caused a ...

    Authors: Anton L Evdonin, Irina V Guzhova, Boris A Margulis and Natalia D Medvedeva

    Citation: Cancer Cell International 2004 4:2

    Content type: Primary research

    Published on:

  5. The aim of this work was to investigate in vitro the putative role of EGR-1 in the growth of glioma cells. EGR-1 expression was examined during the early passages in vitro of 17 primary cell lines grown from 3...

    Authors: Antonella Calogero, Vincenza Lombari, Giorgia De Gregorio, Antonio Porcellini, Severine Ucci, Antonietta Arcella, Riccardo Caruso, Franco Maria Gagliardi, Alberto Gulino, Gaetano Lanzetta, Luigi Frati, Dan Mercola and Giuseppe Ragona

    Citation: Cancer Cell International 2004 4:1

    Content type: Primary research

    Published on:

  6. Styrylpyrone derivative (SPD) is a plant-derived pharmacologically active compound extracted from Goniothalamus sp. Previously, we have reported that SPD inhibited the proliferation of MCF-7 human breast cancer c...

    Authors: Alvin Teck Chien Lee, Hawariah Lope Pihie Azimahtol and Ann Na Tan

    Citation: Cancer Cell International 2003 3:16

    Content type: Primary research

    Published on:

  7. Mast cells are known to accumulate at sites of inflammation and upon activation to release their granule content, e.g. histamine, cytokines and proteases. The secretory leukocyte protease inhibitor (SLPI) is p...

    Authors: Camilla Hollander, Max Nyström, Sabina Janciauskiene and Ulla Westin

    Citation: Cancer Cell International 2003 3:14

    Content type: Primary research

    Published on:

  8. The β-catenin link between membrane-bound cadherins and the actin cytoskeleton regulates cell adhesion and consequently metastasis. Abnormal stabilisation of β-catenin enhances its transcriptional activities. ...

    Authors: Lindsay JG Jones and Rob B Veale

    Citation: Cancer Cell International 2003 3:13

    Content type: Primary research

    Published on:

  9. One of the major cellular serine/threonine protein phosphatases is protein phosphatase type 1 (PP1). Studies employing many eukaryotic systems all point to a crucial role for PP1 activity in controlling cell c...

    Authors: Jay E Reeder, Mark P Sowden, Edward M Messing, Peter Klover, Emma Villa-Moruzzi and John W Ludlow

    Citation: Cancer Cell International 2003 3:12

    Content type: Primary research

    Published on:

  10. Malignant rhabdoid tumors (MRTs) are extremely aggressive and resist current radio- and chemotherapic treatments. To gain insight into the dysfunctions of MRT cells, the apoptotic response of a model cell line...

    Authors: Silvano Nocentini

    Citation: Cancer Cell International 2003 3:11

    Content type: Primary research

    Published on:

  11. Human MCF-7 cells have been studied extensively as a model for breast cancer cell growth. Many reports have established that serum-starved MCF-7 cells can be induced to proliferate upon the sole addition of 17...

    Authors: Irene HL Hamelers, Richard FMA van Schaik, John S Sussenbach and Paul H Steenbergh

    Citation: Cancer Cell International 2003 3:10

    Content type: Primary research

    Published on:

  12. Telomerase is a ribonucleoprotein that synthesizes telomeres and plays an important role in chromosomal stability and cellular immortalisation. Telomerase activity is detectable in most human cancers but not i...

    Authors: Abd E Elkak, Robert F Newbold, Valene Thomas and Kefah Mokbel

    Citation: Cancer Cell International 2003 3:9

    Content type: Primary research

    Published on:

  13. An important physiological function of the normal prostate gland is the synthesis and secretion of a citrate rich prostatic fluid. In prostate cancer, citrate production levels are reduced as a result of alter...

    Authors: Ali Mobasheri, Richard Fox, Iain Evans, Fay Cullingham, Pablo Martín-Vasallo and Christopher S Foster

    Citation: Cancer Cell International 2003 3:8

    Content type: Primary research

    Published on:

  14. The molecular mechanisms by which iron is physiologically transported trough the cellular membranes are still only partially understood. Several studies indicate that a reduction step of ferric iron to ferrous...

    Authors: Silvia Dominici, Lisa Pieri, Mario Comporti and Alfonso Pompella

    Citation: Cancer Cell International 2003 3:7

    Content type: Primary research

    Published on:

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