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  1. To evaluate the prognostic value of pretreatment lymphocyte counts with respect to clinical outcomes in patients with solid tumors.

    Authors: Jiawen Zhao, Weijia Huang, Yongxian Wu, Yihuan Luo, Bo Wu, Jiwen Cheng, Junqiang Chen, Deyun Liu and Chengyang Li
    Citation: Cancer Cell International 2020 20:15
    Content type: Primary research Published on:

  2. Increasing evidence has suggested that microRNAs (miRNAs) act as key post-transcriptional regulators in tumor progression. Previous studies have confirmed that miR-17-5p functions as an oncogene in multiple ca...

    Authors: Jian-Xing Wang, Xin-Ju Jia, Yan Liu, Jin-Hui Dong, Xiu-Min Ren, Ou Xu, Sheng-Hui Liu and Chun-Guang Shan
    Citation: Cancer Cell International 2020 20:14
    Content type: Primary research Published on:

  3. microRNA Let-7 serves as a tumor suppressor by targeting various oncogenic pathways in cancer cells. However, the underlying mechanism of its involvement in breast cancer remains largely unknown. With our rese...

    Authors: Hongbin Wang, Yanlv Ren, Cheng Qian, Jiaxin Liu, Ge Li and Zhigao Li
    Citation: Cancer Cell International 2020 20:13
    Content type: Primary research Published on:

  4. Rapid progression contributes to treatment failure in anaplastic thyroid carcinoma (ATC) patients. In a preliminary study, we demonstrated that some hematopoietic factors may be involved in the progression of ...

    Authors: Zhao-Ming Zhong, Xue Chen, Xiao Qi, Xue-Min Wang, Chun-Yan Li, Ru-Jia Qin, Shi-Qi Wang, Jin Liang, Mu-Sheng Zeng and Chuan-Zheng Sun
    Citation: Cancer Cell International 2020 20:11
    Content type: Primary research Published on:

  5. Accumulating evidence has associated aberrant long non-coding RNAs (lncRNAs) with various human cancers. This study aimed to explore the role of LINC00908 in prostate cancer (PCa) and its possible underlying m...

    Authors: Li Fan, Hai Li and Yun Zhang
    Citation: Cancer Cell International 2020 20:10
    Content type: Primary research Published on:

  6. Aurora kinase A (AURKA) has been implicated in the regulation of cell cycle progression, mitosis and a key number of oncogenic signaling pathways in various malignancies including neuroblastoma. Small molecule...

    Authors: Yan Yang, Lili Ding, Qi Zhou, Li Fen, Yuhua Cao, Junjie Sun, Xuefeng Zhou and Aiguo Liu
    Citation: Cancer Cell International 2020 20:9
    Content type: Primary research Published on:

  7. Accumulating evidence indicates that the long noncoding RNA taurine upregulated gene 1(TUG1) plays a critical role in cancer progression and metastasis. However, the overall biological role and clinical signif...

    Authors: Qun Dai, Jingyi Deng, Jinrong Zhou, Zhuhong Wang, Xiao-feng Yuan, Shunwen Pan and Hong-bin Zhang
    Citation: Cancer Cell International 2020 20:8
    Content type: Primary research Published on:

  8. CTLA-4 is a well-studied immune checkpoint protein that negatively regulates T cell-mediated immune responses. However, the expression of CTLA-4 in glioma and the effects of CTLA-4 on prognosis in patients wit...

    Authors: Fangkun Liu, Jing Huang, Xuming Liu, Quan Cheng, Chengke Luo and Zhixiong Liu
    Citation: Cancer Cell International 2020 20:7
    Content type: Primary research Published on:

  9. LncRNA Brain Cytoplasmic RNA 1 (BCYRN1) has been certified to modulate cancer cells growth and aggressiveness in several tumors. However, research about function of BCYRN1 in hepatocellular carcinoma (HCC) is ...

    Authors: Shichao Ding, Yanfeng Jin, Qingzhi Hao, Yanmeng Kang and Ruiping Ma
    Citation: Cancer Cell International 2020 20:6
    Content type: Primary research Published on:

  10. Ovarian cancer (OC) is a common fatal malignant tumor of female reproductive system worldwide. Growing studies have proofed that circular RNAs (circRNAs) engage in the regulation of various types of cancers. H...

    Authors: Wumei Lin, Haiyan Ye, Keli You and Le Chen
    Citation: Cancer Cell International 2020 20:5
    Content type: Primary research Published on:

  11. The issue of drug resistance in gastric cancer has attracted global attention. TSPAN9, a 4-transmembrane protein that plays an important role in tumor progression and signal transduction, has been found to be ...

    Authors: Yaoyue Qi, Weiwei Qi, Shihai Liu, Libin Sun, Aiping Ding, Guohong Yu, Hui Li, Yixuan Wang, Wensheng Qiu and Jing Lv
    Citation: Cancer Cell International 2020 20:4
    Content type: Primary research Published on:

  12. Ubiquilin-4 (UBQLN4) is a member of the ubiquitin–proteasome system that is usually upregulated in many tumor cells. Its overexpression has been associated with poor disease outcomes in various cancer diseases...

    Authors: Yan Yu, Penglin Xu, Guangying Cui, Xiaodong Xu, Kongfei Li, Xiaolong Chen and Jie Bao
    Citation: Cancer Cell International 2020 20:3
    Content type: Primary research Published on:

  13. Lung adenocarcinoma (LUAD), a widespread histopathological subtype of lung cancer, is deemed as a malignant tumor with a peak risk of mortality. Emerged as RNA with a loop structure that depleted protein codin...

    Authors: Nan Gao and Baoguo Ye
    Citation: Cancer Cell International 2020 20:2
    Content type: Primary research Published on:

  14. Gliomas account for the major part of primary brain tumors. Based on their histology and molecular alternations, adult gliomas have been classified into four grades, each with distinct biology and outcome. Pre...

    Authors: Wenxin Zeng, Zhaohua Tang, Yongguo Li, Guangnian Yin, Zili Liu, Jie Gao, Yan Chen and Feilan Chen
    Citation: Cancer Cell International 2020 20:1
    Content type: Primary research Published on:

  15. Increasing studies have suggested that aberrant expression of microRNAs might play essential roles in the progression of cancers. In this study, we sought to construct a high-specific and superior microRNAs si...

    Authors: Rong Ma, Yanyun Zhao, Miao He, Hongliang Zhao, Yifan Zhang, Shuqi Zhou, Mengcong Gao, Di Di, Jue Wang, Jian Ding and Minjie Wei
    Citation: Cancer Cell International 2019 19:360
    Content type: Primary research Published on:

  16. The editor has retracted this article [1] because Fig. 2f has been duplicated from Fig. 6j in a previously published article [2]. In addition, the article contains sections that substantially overlap with a pr...

    Authors: Jie Song, Wei Zhao, Chang Lu and Xue Shao
    Citation: Cancer Cell International 2019 19:359
    Content type: Retraction Note Published on:

    The original article was published in Cancer Cell International 2019 19:60

  17. The editor has retracted this article [1] because Figures 2 and 4 contain duplicated and modified figures from [2–4]. The data reported in this article are therefore unreliable.

    Authors: Xiaoyan Ding, Wei Sun and Jinglong Chen
    Citation: Cancer Cell International 2019 19:358
    Content type: Retraction Note Published on:

    The original article was published in Cancer Cell International 2018 18:176

  18. Neuroblastoma (NB) is one of most common childhood tumors with high mortality among children worldwide. microRNAs (miRNAs) have been reported to play essential roles in the pathogenesis and therapeutics of NB....

    Authors: Fengxia Mao, Ju Zhang, Xinru Cheng and Qianya Xu
    Citation: Cancer Cell International 2019 19:357
    Content type: Primary research Published on:

  19. The DNA damage and repair pathway is considered a promising target for developing strategies against cancer. RAD51, also known as RECA, is a recombinase that performs the critical step in homologous recombinat...

    Authors: Xiaomeng Zhang, Ningyi Ma, Weiqiang Yao, Shuo Li and Zhigang Ren
    Citation: Cancer Cell International 2019 19:356
    Content type: Primary research Published on:

  20. The purpose of this study was to build functional nomograms based on significant clinicopathological features to predict cause-specific survival (CSS) and overall survival (OS) in patients with stage I–III col...

    Authors: Zheng Zhou, Shaobo Mo, Weixing Dai, Wenqiang Xiang, Lingyu Han, Qingguo Li, Renjie Wang, Lu Liu, Long Zhang, Sanjun Cai and Guoxiang Cai
    Citation: Cancer Cell International 2019 19:355
    Content type: Primary research Published on:

  21. miR-100 has been reported to closely associate with gastric cancer (GC) initiation and progression. However, the underlying mechanism of miR-100-3p in GC is still largely unclear. In this study, we intend to s...

    Authors: Chun-Wei Peng, Ling-Xiao Yue, Yuan-Qin Zhou, Sai Tang, Chen Kan, Lei-Ming Xia, Fan Yang and Si-Ying Wang
    Citation: Cancer Cell International 2019 19:354
    Content type: Primary research Published on:

  24. Gastric cancer (GC) is a common-sighted cancer which is hard to cure over the world. Substantial researches revealed that long non-coding RNAs (lncRNAs) were fundamental regulators in the process of cancers. N...

    Authors: Zhaosheng Chen, Honglei Wu, Zhen Zhang, Guangchun Li and Bin Liu
    Citation: Cancer Cell International 2019 19:351
    Content type: Primary research Published on:

  25. Gastric cancer (GC) is one common cancer which occurs in the stomach leading to high mortality around the world. Long non-coding RNAs (lncRNAs) were found overexpressed or silenced in the occurrence and progre...

    Authors: Hua Zhang, Haitao Huang, Xiaomei Xu, Haiying Wang, Jianxiang Wang, Zuoyi Yao, Xiaoyan Xu, Qian Wu and Fenlan Xu
    Citation: Cancer Cell International 2019 19:350
    Content type: Primary research Published on:

  26. Over the years, long non-coding RNAs (lncRNAs) have been clarified in malignancies, this research was focused on the role of lncRNA cartilage injury-related (lncRNA-CIR) in osteosarcoma cells.

    Authors: Shiwei Liu, Jingchao Li, Liang Kang, Yueyang Tian and Yuan Xue
    Citation: Cancer Cell International 2019 19:349
    Content type: Primary research Published on:

  27. Casticin, an isoflavone compound extracted from the herb Fructus Viticis, has demonstrated anti-inflammatory and anticancer activities and properties. The aim of this study was to investigate the effects and m...

    Authors: Jingxian Liu, Jinghong Yang, Yuhe Hou, Zhenwei Zhu, Jie He, Hao Zhao, Xidong Ye, Dengke Li, Zhaohui Wu, Zhongxi Huang, Bingtao Hao and Kaitai Yao
    Citation: Cancer Cell International 2019 19:348
    Content type: Primary research Published on:

    The Correction to this article has been published in Cancer Cell International 2021 21:138

  28. Ovarian cancer (OC) is a gynecological malignancy with a high mortality. Cisplatin-based treatment is the typical treatment regimen for OC patients; however, it may cause unfavorable resistance. The current st...

    Authors: Hua Guo, Chunfang Ha, Hui Dong, Zhijuan Yang, Yuan Ma and Yonghui Ding
    Citation: Cancer Cell International 2019 19:347
    Content type: Primary research Published on:

  29. Treatments that generate T cell-mediated immunity to a patient’s unique neoantigens are the current holy grail of cancer immunotherapy. In particular, treatments that do not require cumbersome and individualiz...

    Authors: Stephen M. Shaw, Jenny Middleton, Kim Wigglesworth, Amber Charlemagne, Oliver Schulz, Melanie S. Glossop, Giles F. Whalen, Robert Old, Mike Westby, Chris Pickford, Rinat Tabakman, Irit Carmi-Levy, Abi Vainstein, Ella Sorani, Arik A. Zur and Sascha A. Kristian
    Citation: Cancer Cell International 2019 19:346
    Content type: Primary research Published on:

  30. Glioblastoma has been seen as the most common malignancy of brain tumor. Emerging reports has claimed that SNHG29 (LRRC75A-AS1) was involved in several biological processes via modulation of signaling pathway,...

    Authors: Lizhang Han, Zhonggang Li, Yuquan Jiang, Zheng Jiang and Ling Tang
    Citation: Cancer Cell International 2019 19:345
    Content type: Primary research Published on:

  31. Gastric cancer (GC) is one of the most common gastrointestinal malignancies worldwide. Emerging evidence indicates that hyperglycemia promotes tumor progression, especially the processes of migration, invasion...

    Authors: Xin Xu, Bang Chen, Shaopu Zhu, Jiawei Zhang, Xiaobo He, Guodong Cao and Bo Chen
    Citation: Cancer Cell International 2019 19:344
    Content type: Primary research Published on:

  32. The progression of ductal carcinoma in situ (DCIS) into invasive ductal carcinoma (IDC) is prevented by normal breast myoepithelial cells. Studies have suggested that EMT-associated genes were enriched in IDC ...

    Authors: Li Wang, Cong Xu, Xia Liu, Yang Yang, Lu Cao, Guomin Xiang, Fang Liu, Shuling Wang, Jing Liu, Qingxiang Meng, Jiao Jiao and Yun Niu
    Citation: Cancer Cell International 2019 19:343
    Content type: Primary research Published on:

  33. As a novel type of isothiocyanate derived from radish seeds from cruciferous vegetables, sulforaphene (SFE, 4-methylsufinyl-3-butenyl isothiocyanate) has various important biological effects, such as anti-oxid...

    Authors: Chengjuan Zhang, Junxia Zhang, Qiong Wu, Benling Xu, Guoguo Jin, Yan Qiao, Simin Zhao, Yang Yang, Jinwen Shang, Xiaofang Li and Kangdong Liu
    Citation: Cancer Cell International 2019 19:342
    Content type: Primary research Published on:

  34. Circulating tumor cells (CTCs) are a rare subset of cells found in the blood of patients with solid tumors, which function as a seed for metastases. Cancer cells metastasize through the bloodstream either as s...

    Authors: Chang Yang, Bai-Rong Xia, Wei-Lin Jin and Ge Lou
    Citation: Cancer Cell International 2019 19:341
    Content type: Review Published on:

  35. Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, especially in China, with high metastasis and poor prognosis. Recently, as the core component of the polycomb repressive complex...

    Authors: Xiaonian Zhu, Wei Luo, Chunhua Bei, Juan Kong, Shidong Zhang, Yuanyuan Fu, Di Li and Shengkui Tan
    Citation: Cancer Cell International 2019 19:340
    Content type: Primary research Published on:

    The Retraction Note to this article has been published in Cancer Cell International 2020 20:486

  36. Ovarian cancer is one of the leading causes of female death worldwide, with a poor prognosis of advanced patients. Sevoflurane, a volatile anesthetic commonly used in clinical operations, has been reported to ...

    Authors: Chuanfeng Zhang, Baosheng Wang, Xiuqin Wang, Xiugui Sheng and Yongchun Cui
    Citation: Cancer Cell International 2019 19:339
    Content type: Primary research Published on:

  37. The dysregulation of circABCB10 may play an critical role in tumor progression. However, its function in liver cancer (HCC) is still unclear. Therefore, this experimental design is based on circABCB10 to explo...

    Authors: Yu Fu, Limin Cai, Xuexue Lei and Dunwei Wang
    Citation: Cancer Cell International 2019 19:338
    Content type: Primary research Published on:

    The Retraction Note to this article has been published in Cancer Cell International 2020 20:485

  38. Muscle-invasive bladder cancer (MIBC) is originated in the muscle wall of the bladder, and is the ninth most common malignancy worldwide. However, there are no reliable, accurate and robust gene signatures for...

    Authors: Ping-Bao Zhang, Zi-Li Huang, Yong-Hua Xu, Jin Huang, Xin-Yu Huang and Xiu-Yan Huang
    Citation: Cancer Cell International 2019 19:337
    Content type: Primary research Published on:

  39. Autophagy is an evolutionarily conserved process through which cells degrade and recycle cytoplasm. The relation among autophagy, apoptosis and tumor is highly controversial until now and the molecular mechani...

    Authors: Jing Liu, Shuaiyu Long, Huanan Wang, Nannan Liu, Chuchu Zhang, Lingling Zhang and Yingjie Zhang
    Citation: Cancer Cell International 2019 19:336
    Content type: Primary research Published on:

  40. The high prevalence of alternative splicing among genes implies the importance of genomic complexity in regulating normal physiological processes and diseases such as gastric cancer (GC). The standard form of ...

    Authors: Wei-zhao Peng, Ji-xi Liu, Chao-feng Li, Ren Ma and Jian-zheng Jie
    Citation: Cancer Cell International 2019 19:335
    Content type: Primary research Published on:

  41. Endometrial carcinoma (EC) accounts for 5.8% of all cancers in Saudi females. Although most ECs are sporadic, 2–5% tend to be familial, being associated with Lynch syndrome and Cowden syndrome. In this study, ...

    Authors: Abdul K. Siraj, Sandeep Kumar Parvathareddy, Rong Bu, Kaleem Iqbal, Sarah Siraj, Tariq Masoodi, Rica Micaela Concepcion, Laila Omar Ghazwani, Ismail AlBadawi, Fouad Al-Dayel and Khawla S. Al-Kuraya
    Citation: Cancer Cell International 2019 19:334
    Content type: Primary research Published on:

  43. Abiraterone and MDV3100 are two effective anticancer agents for prostate cancer, however, the mechanism of their downstream action remains undefined.

    Authors: Jingli Han, Junhua Zhang, Wei Zhang, Dalei Zhang, Ying Li, Jinsong Zhang, Yaqun Zhang, Tongxiang Diao, Luwei Cui, Wenqing Li, Fei Xiao, Ming Liu and Lihui Zou
    Citation: Cancer Cell International 2019 19:332
    Content type: Primary research Published on:

  45. Abnormal activation of the classic Wnt signaling pathway is closely related to the occurrence of epithelial cancers. B-cell lymphoma 9 (BCL9), a transcription factor, is a novel oncogene discovered in the clas...

    Authors: Jing Wang, Mingjun Zheng, Liancheng Zhu, Lu Deng, Xiao Li, Linging Gao, Caixia Wang, Huimin Wang, Juanjuan Liu and Bei Lin
    Citation: Cancer Cell International 2019 19:330
    Content type: Primary research Published on:

  46. Hepatocellular carcinoma (HCC) is the most prevalent type of malignant liver disease worldwide. Molecular changes in HCC collectively contribute to Wnt/β-catenin, as a tumor proliferative signaling pathway, to...

    Authors: Jafar Ai, Neda Ketabchi, Javad Verdi, Nematollah Gheibi, Hossein Khadem Haghighian and Maria Kavianpour
    Citation: Cancer Cell International 2019 19:329
    Content type: Review Published on:

  47. Circular RNA Itchy E3 ubiquitin protein ligase (Circ-ITCH) is significantly down-regulated in various kinds of tumors, however, the mechanisms of action and functions of circITCH gene in prostate cancer (PC) a...

    Authors: Xuegang Wang, Rong Wang, Zhun Wu and Peide Bai
    Citation: Cancer Cell International 2019 19:328
    Content type: Primary research Published on:

  48. The aim of this study was to investigate the regulatory network of lncRNAs as competing endogenous RNAs (ceRNA) in bladder urothelial carcinoma (BUC) based on gene expression data derived from The Cancer Genom...

    Authors: Jiawu Wang, Chengyao Zhang, Yan Wu, Weiyang He and Xin Gou
    Citation: Cancer Cell International 2019 19:327
    Content type: Primary research Published on:

  49. Spindle and kinetochore associated protein 1 (SKA1) is a protein involved in chromosome congression and mitosis. It has been found to be upregulated and oncogenic in several human cancers. Herein, we investiga...

    Authors: Xizhao Wang, Yu Zeng, Mingfeng Zhou, Xian Zhang, Anqi Xu, Jie Lin, Zhiyong Wu, Cheng Xie, Jie Luo, Shengfeng Ding, Zhengming Zhan, Hao Long and Ye Song
    Citation: Cancer Cell International 2019 19:324
    Content type: Primary research Published on:

  50. Autologous tumor-infiltrating lymphocytes (Tils) immunotherapy is a promising treatment in patients with advanced hepatocellular cancer. Although Tils treatment has shown great promise, their persistence and t...

    Authors: Benling Xu, Long Yuan, Guangyu Chen, Tiepeng Li, Jinxue Zhou, Chengjuan Zhang, Peng Qin, Musleh M. Muthana, Shengdian Wang, Xuexiang Du and Quanli Gao
    Citation: Cancer Cell International 2019 19:322
    Content type: Primary research Published on:
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