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  1. A human malignant continuous cell line, named NG97, was recently established in our laboratory. This cell line has been serially subcultured over 100 times in standard culture media presenting no sign of cell ...

    Authors: Camila ML Machado, André Schenka, José Vassallo, Wirla MSC Tamashiro, Estela M Gonçalves, Selma C Genari and Liana Verinaud

    Citation: Cancer Cell International 2005 5:13

    Content type: Primary research

    Published on:

  2. The effects of an omega-3 (n-3) fatty acid enriched diet alone and in combination with gamma irradiation (IR) therapy in nude mice bearing a human MDA-MB231 breast cancer xenograft were tested. The cancer cell...

    Authors: W Elaine Hardman, LuZhe Sun, Nicholas Short and Ivan L Cameron

    Citation: Cancer Cell International 2005 5:12

    Content type: Primary research

    Published on:

  3. Inflammatory breast cancer (IBC) is the most lethal form of locally invasive breast cancer known. However, very little information is available on the cellular mechanisms responsible for manifestation of the I...

    Authors: Michaela R Hoffmeyer, Kristin M Wall and Suranganie F Dharmawardhane

    Citation: Cancer Cell International 2005 5:11

    Content type: Primary research

    Published on:

  4. The almost universal belief that cancer is caused by mutation may gradually be giving way to the belief that cancer begins as a cellular adaptation that involves the local epigenetic silencing of various genes...

    Authors: Richmond T Prehn

    Citation: Cancer Cell International 2005 5:9

    Content type: Hypothesis

    Published on:

  5. Androgens and androgen receptors (AR) regulate normal prostate development and growth. They also are involved in pathological development of prostatic diseases, including benign prostatic hyperplasia (BPH) and...

    Authors: Qing Yang, Kar-Ming Fung, Wanda V Day, Bradley P Kropp and Hsueh-Kung Lin

    Citation: Cancer Cell International 2005 5:8

    Content type: Primary research

    Published on:

  6. Calcineurin (CaN) is an important serine-threonine phosphatase (PP2B), which plays a crucial role in calcium-calmodulin mediated signal transduction events. Calcineurin has been implicated in pathogenesis of v...

    Authors: S Padma, A Pavani Sowjanya, Usha Rani Poli, Meenakshi Jain, BN Rao and Gayatri Ramakrishna

    Citation: Cancer Cell International 2005 5:7

    Content type: Primary research

    Published on:

  7. A full-term pregnancy has been associated with reduced risk for developing breast cancer. In rodent models, the protective effect of pregnancy can be mimicked with a defined regimen of estrogen and progesteron...

    Authors: Jiahui Zhang, Yifan Tu and Sallie Smith-Schneider

    Citation: Cancer Cell International 2005 5:6

    Content type: Primary research

    Published on:

  8. The necessary and sufficient capabilities of cancer cell have been identified. Strikingly, this list does not include one that would seem to be a key property, namely the ability of cancer cells to kill their ...

    Authors: Anatoly V Lichtenstein

    Citation: Cancer Cell International 2005 5:5

    Content type: Hypothesis

    Published on:

  9. Melanoma inhibitory activity (MIA) is a small secreted protein that interacts with extracellular matrix proteins. Its over-expression promotes the metastatic behavior of malignant melanoma, thus making it a po...

    Authors: Jamael El Fitori, Jörg Kleeff, Nathalia A Giese, Ahmed Guweidhi, Anja K Bosserhoff, Markus W Büchler and Helmut Friess

    Citation: Cancer Cell International 2005 5:3

    Content type: Primary research

    Published on:

  10. Most cancer cells are characterized by mobile lipids visible on proton NMR (1H-NMR), these being comprised mainly of methyl and methylene signals from lipid acyl chains. Erythroleukemia K562 cells show narrow sig...

    Authors: Aurélie Mannechez, Paiboon Reungpatthanaphong, Jacques D de Certaines, Geneviève Leray and Laurence Le Moyec

    Citation: Cancer Cell International 2005 5:2

    Content type: Primary research

    Published on:

  11. Breast cancer cells frequently metastasize to the skeleton and induce extensive bone destruction. Cancer cells produce proteinases, including matrix metalloproteinases (MMPs) and the plasminogen activator syst...

    Authors: Hayley Morgan and Peter A Hill

    Citation: Cancer Cell International 2005 5:1

    Content type: Primary research

    Published on:

  12. Tumor microenvironment, which is largely affected by inflammatory cells, is a crucial participant in the neoplastic process through promotion of cell proliferation, survival and migration. We measured the effe...

    Authors: Inga Zelvyte, Tim Stevens, Ulla Westin and Sabina Janciauskiene

    Citation: Cancer Cell International 2004 4:7

    Content type: Primary research

    Published on:

  13. Heptaplatin is a new platinum derivative with anticancer activity against various cancer cell lines, including cisplatin-resistant cancer cell lines (Cancer Chemother Pharmacol 1995; 35: 441).

    Authors: Cheol-Hee Choi, Yoon-Jung Cha, Chun-San An, Kyung-Jong Kim, Kweon-Cheon Kim, Sung-Pyo Moon, Zang Hee Lee and Young-Don Min

    Citation: Cancer Cell International 2004 4:6

    Content type: Primary research

    Published on:

  14. Prostate cancer is the second leading cause of male death in the United States. The incidence increases most rapidly with age, and multiple genetic and epigenetic factors have been implicated in the initiation...

    Authors: James Kumi-Diaka, Simone Saddler-Shawnette, Alex Aller and Jayann Brown

    Citation: Cancer Cell International 2004 4:5

    Content type: Primary research

    Published on:

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