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  1. Despite recent advances, multiple myeloma (MM) remains incurable. However, the appearance of allogeneic stem cell transplantation (allo-SCT) through graft-versus-myeloma effect provides a potential way to cure...

    Authors: Xuejiao Yin, Liang Tang, Fengjuan Fan, Qinyue Jiang, Chunyan Sun and Yu Hu
    Citation: Cancer Cell International 2018 18:62
  2. Recently, long non-coding RNA (lncRNA) MIAT has been demonstrated as an oncogenic gene in several types of cancer. However, the role and mechanism of MIAT in colorectal cancer (CRC) have not been investigated.

    Authors: Zhaoxia Liu, Hai Wang, Hongwei Cai, Ye Hong, Yan Li, Dongming Su and Zhining Fan
    Citation: Cancer Cell International 2018 18:59
  3. Immunotoxins are typical therapeutic drugs that can target cancer cells. They exploit the affinity of specific monoclonal antibodies or ligands to cancer cells to deliver a conjugated protein toxin to target s...

    Authors: Miaonan Sun, Liankun Sun, Dejun Sun, Chunmei Zhang and Mei Li
    Citation: Cancer Cell International 2018 18:58
  4. Metastatic dissemination of solid tumors is often initiated by reactivation of an embryonic development program, epithelial-to-mesenchymal-transition (EMT). EMT has been associated with acquiring invasiveness ...

    Authors: Mamta Singla, Ajay Kumar, Amanjit Bal, Subhendu Sarkar and Shalmoli Bhattacharyya
    Citation: Cancer Cell International 2018 18:57
  5. Renal cell carcinoma accounts for 2–3% of all cancers and metastasis increased the malignancy of renal cancer. However, the role of methylation in metastasis of renal cancer is poorly understood.

    Authors: Jianbo Zheng, Yanhui Mei, Ping Xiang, Guangsheng Zhai, Ning Zhao, Chuanbing Xu, Min Liu, Zhengsheng Pan, Kai Tang and Dongsheng Jia
    Citation: Cancer Cell International 2018 18:56
  6. After publication of the original article (1) it was noted that the author details and affiliations of this manuscript contained minor errors in the institution addresses.

    Authors: Yue Li, You Li, Yao Chen, Qian Xie, Ningning Dong, Yanjun Gao, Huan Deng, Chunhua Lu and Suihai Wang
    Citation: Cancer Cell International 2018 18:55

    The original article was published in Cancer Cell International 2017 17:102

  7. Paired box gene 8 (PAX8) is expressed in and indispensable to thyroid development. MiR-144-3p is found dys-regulated in cancers, and it can block the expression of target gens. This study sought to understand ...

    Authors: Chang Liu, Chang Su, Yanchun Chen and Guang Li
    Citation: Cancer Cell International 2018 18:54
  8. Signal transducer and activator of transcription 3 (STAT3) is persistently activated in a wide variety of epithelial cancers. Aberrant activity of STAT3 correlates with tumor growth, invasion and metastasis, w...

    Authors: Chao Zhou, Jie Ma, Mengyuan Su, Dan Shao, Jianan Zhao, Tongjian Zhao, Zhuoyao Song, Yan Meng and Ping Jiao
    Citation: Cancer Cell International 2018 18:53
  9. Endometrial cancer (EC) is the fourth most common malignancy of the female genital tract worldwide. MicroRNAs are important gene regulators with critical roles in diverse biological processes, including tumori...

    Authors: JinHui Liu, ChunYu Li, Yi Jiang, YiCong Wan, ShuLin Zhou and WenJun Cheng
    Citation: Cancer Cell International 2018 18:51
  10. Gastric cancer presents a major health burden worldwide. Therefore, many molecular targeting agents have been evaluated for treatment of gastric cancer. Gefitinib has shown anticancer activity against gastric ...

    Authors: Jia Huafeng, Zhang Deqing, Ding Yong, Zhang Yulian and Hu Ailing
    Citation: Cancer Cell International 2018 18:50
  11. Osteosarcoma (OS) is a rare, malignant bone tumor that primarily affects adolescents and has a high degree of malignancy and high incidence of recurrence and metastasis. Our study aimed to explore the role of ...

    Authors: Riliang Cao, Jianli Shao, Yabin Hu, Liang Wang, Zhizhong Li, Guodong Sun and Xiaoliang Gao
    Citation: Cancer Cell International 2018 18:49

    The Correction to this article has been published in Cancer Cell International 2021 21:560

  12. Secreted frizzled-related protein 1 (SFRP1) is a member of the SFRPs family that modulates the Wnt signal transduction pathway. Recent studies have showed down-regulation of SFRP1 expression in colorectal canc...

    Authors: Zhongchuan Wang, Rujia Li, Yongshan He and Shiyong Huang
    Citation: Cancer Cell International 2018 18:48
  13. Long noncoding RNAs (lncRNAs) have been reported to have potential diagnostic and prognostic values for numerous cancers. However, the plasma expression of lncRNA BLACAT1 and its clinical value in patients wit...

    Authors: Denghui Liao, Gang Lv, Ting Wang, Jie Min, Yadong Wang and Shengchun Liu
    Citation: Cancer Cell International 2018 18:47
  14. Abnormally high expression of the mammalian de novo lipogenesis (DNL) pathway in various cancer cells promotes cell over-proliferation and resistance to apoptosis. Inhibition of key enzymes in the DNL pathway,...

    Authors: Phuriwat Khiewkamrop, Pattamaphron Phunsomboon, Lysiane Richert, Dumrongsak Pekthong and Piyarat Srisawang
    Citation: Cancer Cell International 2018 18:46
  15. Abnormal expression of long non-coding RNA (lncRNAs) often facilitates unrestricted growth of cancer cells. Long intergenic non-protein coding RNA 1510, an enhancer lncRNA (LINC01510), a lncRNA enhancer is upr...

    Authors: Chaoqun Cen, Jian Li, Jingjing Liu, Mingshi Yang, Tianyi Zhang, Yu Zuo, Changwei Lin and Xiaorong Li
    Citation: Cancer Cell International 2018 18:45
  16. Despite new progress of chemotherapy in multiple myeloma (MM) clinical treatment, MM is still a refractory disease and new technology is needed to improve the outcomes and prolong the survival. Cold atmospheri...

    Authors: Dehui Xu, Yujing Xu, Ning Ning, Qingjie Cui, Zhijie Liu, Xiaohua Wang, Dingxin Liu, Hailan Chen and Michael G. Kong
    Citation: Cancer Cell International 2018 18:42
  17. The abnormal expression of non-coding RNAs (ncRNAs), such as microRNAs and long ncRNAs, often contribute to the development of cancers. miR-200c functions as a tumour suppressor that impacts the growth of blad...

    Authors: Ran Xu, Xuan Zhu, Fangzhi Chen, Changkun Huang, Kai Ai, Hongtao Wu, Lei Zhang and Xiaokun Zhao
    Citation: Cancer Cell International 2018 18:41
  18. Low expression of E2F3a and caspase 8 associated protein 2 (CASP8AP2) are associated with poor prognosis of childhood acute lymphoblastic leukemia (ALL).

    Authors: Fei-Fei Liu, Kai-Ling Wang, Li-Ping Deng, Xiao Liu, Min-yuan Wu, Tian-You Wang, Lei Cui and Zhi-Gang Li
    Citation: Cancer Cell International 2018 18:40
  19. MicroRNA-21 (miR-21) was previously reported being dysregulated in many kinds of cancer including esophageal squamous cell carcinoma (ESCC). In the present study, we aimed to investigate the role of miR-21 in ...

    Authors: Fang Li, Jia-Hua Lv, Long Liang, Jun-chao Wang, Chu-Rong Li, Lei Sun and Tao Li
    Citation: Cancer Cell International 2018 18:39
  20. Esophageal squamous cell carcinoma (ESCC) is one of the prevalent and deadly cancers worldwide, especially in China. Considering the poor prognosis of ESCC, the aim of this study is to dissect the effects of l...

    Authors: Bin Liu, Chun-Feng Pan, Guo-Liang Yao, Ke Wei, Yang Xia and Yi-Jiang Chen
    Citation: Cancer Cell International 2018 18:38
  21. MicroRNAs (miRNAs) are endogenous, small non-coding RNAs that play important roles in multiple biological processes. Here, we show that miRNAs play an important function in the down-regulation of FAS expressio...

    Authors: Masanori Kawano, Kazuhiro Tanaka, Ichiro Itonaga, Tatsuya Iwasaki and Hiroshi Tsumura
    Citation: Cancer Cell International 2018 18:37
  22. Rab11 family-interacting protein 2 (Rab11-FIP2) can interact with MYO5B and plays an important role in regulating plasma membrane recycling. However, little is known about the clinical significance of DUSP2 in...

    Authors: Wenjie Dong and Xinai Wu
    Citation: Cancer Cell International 2018 18:35
  23. The aberrant expression of long non-coding RNA (lncRNA) X inactivate-specific transcript (XIST) has been demonstrated to be involved in the tumourigenesis and the development of various cancers. Therefore, we ...

    Authors: Huihui Mao, Kai Wang, Yuehua Feng, Jun Zhang, Lili Pan, Yuxia Zhan, Haijun Sheng and Guanghua Luo
    Citation: Cancer Cell International 2018 18:34
  24. Apoptosis plays an important role in the development and homeostasis of multicellular organisms and its deregulation may result in many serious diseases, including cancer. Now it is clear that some oncogenic m...

    Authors: Andrea Vazanova, Jana Jurecekova, Tomas Balharek, Juraj Marcinek, Jan Stasko, Anton Dzian, Lukas Plank, Pavol Zubor, Peter Racay and Jozef Hatok
    Citation: Cancer Cell International 2018 18:33
  25. Integrins play a critical role in carcinogenesis. Integrin β1 localization is regulated by the guanosine-5′-triphosphate hydrolase Rab25 and integrin β1 levels are elevated in the serum of colon cancer patient...

    Authors: Kyung Sook Hong, Eun-Young Jeon, Soon Sup Chung, Kwang Ho Kim and Ryung-Ah Lee
    Citation: Cancer Cell International 2018 18:32
  26. Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma (RCC), and is frequently accompanied by the genetic features of von Hippel–Lindau (VHL) loss. VHL loss increases the e...

    Authors: Yongchang Lai, Zhijian Zhao, Tao Zeng, Xiongfa Liang, Dong Chen, Xiaolu Duan, Guohua Zeng and Wenqi Wu
    Citation: Cancer Cell International 2018 18:31
  27. Store-operated Ca2+ entry (SOCE) has been implicated in the migration of some cancer cell lines. The canonical SOCE is defined as the Ca2+ entry that occurs in response to near-maximal depletion of Ca2+ within th...

    Authors: Priyodarshan Goswamee, Tamar Pounardjian and David R. Giovannucci
    Citation: Cancer Cell International 2018 18:30
  28. New drugs for adrenocortical carcinoma (ACC) are needed because most patients undergo rapid disease progression despite surgery and adjuvant therapy with mitotane. In this study, we aimed to investigate the in...

    Authors: Elaine Silveira, Isadora Pontes Cavalcante, Jean Lucas Kremer, Pedro Omori Ribeiro de Mendonça and Claudimara Ferini Pacicco Lotfi
    Citation: Cancer Cell International 2018 18:29
  29. CD44 encoded by a single gene is a cell surface transmembrane glycoprotein. Exon 2 is one of the important exons to bind CD44 protein to hyaluronan. Experimental evidences show that hyaluronan–CD44 interaction...

    Authors: Rezvan Esmaeili, Nasrin Abdoli, Fatemeh Yadegari, Mohamadreza Neishaboury, Leila Farahmand, Ahmad Kaviani and Keivan Majidzadeh-A
    Citation: Cancer Cell International 2018 18:28
  30. Lung cancer is a malignant tumor with the highest incidence and mortality around the world. Recent advances in RNA sequencing technology have enabled insights into long non-coding RNAs (lncRNAs), a previously ...

    Authors: Xuehai Wang, Gang Li, Qingsong Luo, Jiayong Xie and Chongzhi Gan
    Citation: Cancer Cell International 2018 18:27
  31. Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm whose pathogenesis is linked to the Philadelphia chromosome presence that generates the BCRABL1 fusion oncogene. Tyrosine kinase inhibitors ...

    Authors: Doralina do Amaral Rabello, Vivian D’Afonseca da Silva Ferreira, Maria Gabriela Berzoti-Coelho, Sandra Mara Burin, Cíntia Leticia Magro, Maira da Costa Cacemiro, Belinda Pinto Simões, Felipe Saldanha-Araujo, Fabíola Attié de Castro and Fabio Pittella-Silva
    Citation: Cancer Cell International 2018 18:26
  32. Cholangiocarcinoma (CCA) is one of the worst prognosis cancer. The survival time of CCA patients is related to serum estrogen levels and estrogen has been found to enhance the proliferation and invasiveness of...

    Authors: Ekapot Singsuksawat, Chanitra Thuwajit, Komgrid Charngkaew and Peti Thuwajit
    Citation: Cancer Cell International 2018 18:25
  33. Pro-oxidant drugs have been proposed for treating certain cancers but the resistance developed by cancer cells to oxidative stress limits its potential use in clinics. To understand the mechanisms underlying r...

    Authors: Christophe Glorieux and Pedro Buc Calderon
    Citation: Cancer Cell International 2018 18:24
  34. Cholesterol in lipid raft plays crucial role on cancer cell survival during metastasis of cancer cells. Cancer cells are reported to enrich cholesterol in lipid raft which make them more susceptible to cell de...

    Authors: Mukesh Kumar, Karuna Irungbam and Meena Kataria
    Citation: Cancer Cell International 2018 18:23
  35. Increasing evidence indicates that PIM1 is a potential prognostic marker and target for cancer treatment but its precise mechanisms of action remain to be determined in salivary adenoid cystic carcinoma (SACC)...

    Authors: Jiajie Xu, Xin Zhu, Qingling Li, Chao Chen, Zhenying Guo, Zhuo Tan, Chuanming Zheng and Minghua Ge
    Citation: Cancer Cell International 2018 18:22
  36. We ought to explore the acquired somatic alterations, shedding light on genetic basis of somatic alterations in NB patients with chemotherapy.

    Authors: Chao Duan, Han Wang, Ying Chen, Ping Chu, Tianyu Xing, Chao Gao, Zhixia Yue, Jie Zheng, Mei Jin, Weiyue Gu and Xiaoli Ma
    Citation: Cancer Cell International 2018 18:21
  37. Papillary thyroid carcinoma (PTC) is one of the most frequent malignancies of the endocrine system, whose mechanisms of pathogenesis, progression and prognosis are still far from being clearly elucidated. Desp...

    Authors: Feng Chen, Yaqiong Jin, Lin Feng, Jie Zhang, Jun Tai, Jin Shi, Yongbo Yu, Jie Lu, Shengcai Wang, Xin Li, Ping Chu, Shujing Han, Shujun Cheng, Yongli Guo and Xin Ni
    Citation: Cancer Cell International 2018 18:20
  38. Visfatin has been reported to be associated with breast cancer progression, but the interaction between the visfatin and clinicopathologic factors in breast cancer progression status requires further investiga...

    Authors: Sin-Hua Moi, Yi-Chen Lee, Li-Yeh Chuang, Shyng-Shiou F. Yuan, Fu Ou-Yang, Ming-Feng Hou, Cheng-Hong Yang and Hsueh-Wei Chang
    Citation: Cancer Cell International 2018 18:19
  39. The ability to metastasize is one of the most important characteristics of neoplastic cells. An imbalance between the action of some matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs drives the in...

    Authors: Renato F. Ivanovic, Nayara I. Viana, Denis R. Morais, Iran A. Silva, Katia R. Leite, José Pontes-Junior, Gustavo Inoue, William C. Nahas, Miguel Srougi and Sabrina T. Reis
    Citation: Cancer Cell International 2018 18:18
  40. After publication of the original article [1] it was noted that the names of two authors, Han-Juan Xiao and Jun-Ming Hu were incorrectly published as Hai-Juan Xiao and Jun-Ming Hou. These errors were introduce...

    Authors: Jin Li, Yuan Wang, Cheng-Gong Zhang, Han-Juan Xiao, Jun-Ming Hu and Jing-Dong He
    Citation: Cancer Cell International 2018 18:17

    The original article was published in Cancer Cell International 2018 18:4

  41. Recent studies have shown that laminin subunit alpha 4 (LAMA4) plays an important role in carcinogenesis. However, its molecular biological function in triple-negative breast cancer (TNBC) has not been entirel...

    Authors: Zhi-Xue Yang, Bo Zhang, Jinrong Wei, Guo-Qin Jiang, Yan-Lin Wu, Bing-Jing Leng and Chun-Gen Xing
    Citation: Cancer Cell International 2018 18:16
  42. The antitumoral effects of different Toll-like receptor (TLRs) agonists is mediated by activating immune responses to suppress tumors growth, although TLR ligands may also have a direct effect on tumoral cells...

    Authors: Eva Villamón, Javier González-Fernández, Esperanza Such, José Vicente Cervera, Daniel Gozalbo and M. Luisa Gil
    Citation: Cancer Cell International 2018 18:15
  43. p53 is a tumor suppressor and key regulator of glycolysis in cancer cells, however highly mutated in tumors. In ovarian cancer, studies concerning p53 mutations focus on the DNA binding domain since the majori...

    Authors: Stephanie Antoun, David Atallah, Roula Tahtouh, Nada Alaaeddine, Malak Moubarak, Abir Khaddage, Eliane Nasr Ayoub, George Chahine and George Hilal
    Citation: Cancer Cell International 2018 18:14
  44. G protein-coupled receptors (GPR) are involved in a wide range of physiological processes, some of which, however, can be hijacked by tumor cells. Over-expression of G protein-coupled receptors 137 (GPR137) ar...

    Authors: Li-Jie Men, Ji-Zhu Liu, Hai-Ying Chen, Li Zhang, Shuang-Feng Chen, Tai-Wu Xiao, Jing-Xia Wang, Guang-Yao Li and Ya-Ping Wu
    Citation: Cancer Cell International 2018 18:13
  45. Triple-negative breast cancer is a biological subtype of breast cancer, which is unresponsive to conventional chemotherapies and has a poor prognosis. C-Phycocyanin (C-PC), a marine natural purified from Spirulin...

    Authors: Liangqian Jiang, Yujuan Wang, Guoxiang Liu, Huihui Liu, Feng Zhu, Huanhuan Ji and Bing Li
    Citation: Cancer Cell International 2018 18:12

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