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  1. Triple-receptor negative breast cancer (TNBC) is an aggressive breast tumor subtype that generally has a poor prognosis. This study aimed to investigate the role and regulatory mechanisms of Zinc finger MIZ-ty...

    Authors: Xiaopan Zou, Yan Liu, Jun Di, Wei Wei, Nobumoto Watanabe, Jiang Li and Xiaomeng Li
    Citation: Cancer Cell International 2022 22:52
  2. Colorectal cancer (CRC) is a malignant tumor affecting people worldwide. Long noncoding RNAs (lncRNAs) is a crucial factor modulating various cancer progression, including CRC. Long intergenic non-protein codi...

    Authors: Shoushan Nan, Shuangxia Zhang, Rong Jin and Juelei Wang
    Citation: Cancer Cell International 2022 22:51
  3. Gastric cancer (GC) has a poor prognosis and limited therapeutic options. As a new promising cancer therapeutic approach, chimeric antigen receptor (CAR)-T cells represent a potential GC treatment. We investig...

    Authors: Fengqiang Sun, Xiaomei Yu, Ruixue Ju, Zhanzhao Wang and Yuhui Wang
    Citation: Cancer Cell International 2022 22:50
  4. The function of spindle apparatus coiled-coil protein 1 (SPDL1) as a cancer-promoting gene has been reported in a number of studies. However, the pan-cancer analysis of SPDL1 is still lacking. Here, we perform...

    Authors: Peng Song, Dilinaer Wusiman, Fenglan Li, Xiaoxuan Wu, Lei Guo, Wenbin Li, Shugeng Gao and Jie He
    Citation: Cancer Cell International 2022 22:49
  5. N6-Methyladenosine (m6A), the most abundant internal modification associated with eukaryotic mRNAs, has emerged as a dynamic regulatory mechanism controlling the expression of genes involved in many physiologica....

    Authors: Shanshan Wang, Wei Lv, Tao Li, Shubing Zhang, Huihui Wang, Xuemei Li, Lianzi Wang, Dongyue Ma, Yan Zang, Jilong Shen, Yuanhong Xu and Wei Wei
    Citation: Cancer Cell International 2022 22:48
  6. Authors: Fan Luo, Jiaxin Cao, Feiteng Lu, Kangmei Zeng, Wenjuan Ma, Yan Huang, Li Zhang and Hongyun Zhao
    Citation: Cancer Cell International 2022 22:46

    The original article was published in Cancer Cell International 2021 21:458

  7. Authors: Ishita Gupta, Gheyath K. Nasrallah, Anju Sharma, Ayesha Jabeen, Maria K. Smatti, Hamda A. Al-Thawadi, Ali A. Sultan, Moussa Alkhalaf, Semir Vranic and Ala-Eddin Al Moustafa
    Citation: Cancer Cell International 2022 22:45

    The original article was published in Cancer Cell International 2020 20:107

  8. Malignant melanoma (MM) is highly metastatic and has the highest mortality rate in patients with skin cancer. The ERBB3 binding protein 1 (Ebp1) has been linked to the onset and progression of a number of mali...

    Authors: Yanqiu Bao, Jingshu Cui, Yuyang Yue, Shuxia Cao, Xiangdan Li and Lan Liu
    Citation: Cancer Cell International 2022 22:44
  9. N-[2-(5-methoxy-1H-indol-3-yl) ethyl] or simply melatonin is a biogenic amine produced by pineal gland and recently recognized various other organs. Because of a broad range of biological function melatonin is co...

    Authors: Mohammad Mirza-Aghazadeh-Attari, Ainaz Mihanfar, Bahman Yousefi and Maryam Majidinia
    Citation: Cancer Cell International 2022 22:43
  10. Despite advances in the development of efficient chemotherapy, the treatment of colorectal cancer (CRC) remains a challenge due to acquired chemoresistance. It has been reported that microRNAs (miRNAs) dysregu...

    Authors: Hu Han, Yan Li, Wan Qin, Lu Wang, Han Yin, Beibei Su and Xianglin Yuan
    Citation: Cancer Cell International 2022 22:42
  11. Rearrangements involving the fibroblast growth factor receptor 1 (FGFR1) gene result in 8p11 myeloproliferative syndrome (EMS), which is a rare and aggressive hematological malignancy that is often initially d...

    Authors: Xuehong Zhang, Furong Wang, Fanzhi Yan, Dan Huang, Haina Wang, Beibei Gao, Yuan Gao, Zhijie Hou, Jiacheng Lou, Weiling Li and Jinsong Yan
    Citation: Cancer Cell International 2022 22:40
  12. Theabrownin (TB) is a bioactive component of tea and has been reported to exert effects against many human cancers, but its efficacy and mechanism on hepatocellular carcinoma (HCC) with different p53 genotypes...

    Authors: Jiaan Xu, Xiujuan Xiao, Bo Yan, Qiang Yuan, Xiaoqiao Dong, Quan Du, Jin Zhang, Letian Shan, Zhishan Ding, Li Zhou and Thomas Efferth
    Citation: Cancer Cell International 2022 22:39
  13. The tumour heterogeneous make-up of immune cell infiltrates is a key factor for the therapy response and prognosis of hepatocellular carcinoma (HCC). However, it is still a major challenge to comprehensively u...

    Authors: Juan Lu, Yanfei Chen, Xiaoqian Zhang, Jing Guo, Kaijin Xu and Lanjuan Li
    Citation: Cancer Cell International 2022 22:38
  14. To determine whether concurrent chemotherapy is necessary during locoregional radiotherapy (RT) after palliative chemotherapy (PCT) in patients with de novo metastatic nasopharyngeal carcinoma (mNPC).

    Authors: Shuo-Han Zheng, Yu-Tong Wang, Song-Ran Liu, Zi-Lu Huang, Guan-Nan Wang, Jin-Tao Lin, Shi-Rong Ding, Chen Chen and Yun-Fei Xia
    Citation: Cancer Cell International 2022 22:36
  15. Golgi phosphoprotein 3 (GOLPH3) has been frequently reported as an oncoprotein in a variety of tumors. However, its role in the cancer-associated intercellular signaling communication has not yet been explored...

    Authors: Ying Gao, Zheng Yin, Yunling Qi, Hong Peng, Wenbin Ma, Ruizhi Wang and Wen Li
    Citation: Cancer Cell International 2022 22:35
  16. Silencing of the periostin gene (POSTN) can inhibit the biological process of several different cancers, and this inhibition may be related to down-regulation of PI3K/AKT signaling. However, the effect of POSTN o...

    Authors: Chaojian Xu, Ziyue Wang, Long Zhang, Yi Feng, Jia Lv, Zhuangzhuang Wu, Rong Yang, Taiyong Wu, Jian Li, Ruhao Zhou, Zhi Tian, Junjun Bai, Huadong Zhang, Yanping Lan and Zhi Lv
    Citation: Cancer Cell International 2022 22:34
  17. Epigenetic reprogramming reportedly has a crucial role in prostate cancer (PCa) progression. RNA modification is a hot topic in epigenetics, and N6-methyladenosine (m6A) accounts for approximately 60% of RNA c...

    Authors: Yongjun Quan, Xiaodong Zhang and Hao Ping
    Citation: Cancer Cell International 2022 22:33
  18. Glioblastoma is one of the most common fatal intracranial malignancies. Lysine-specific demethylase 1 (LSD1) reportedly has therapeutic effects on a variety of tumors. This study explored the therapeutic effec...

    Authors: Wei Li, Bai-sheng Huang, Yuan-yuan Xiong, Li-jian Yang and Li-xiang Wu
    Citation: Cancer Cell International 2022 22:32
  19. Non-small cell lung cancer (NSCLC) is still one of the diseases with the highest mortality and morbidity, and lung adenocarcinoma (LUAD) accounts for more than half of all NSCLC cases in most countries. miRNA ...

    Authors: Zijian Ma, Ganyi Chen, Yiqian Chen, Zizhang Guo, Hao Chai, Yu Tang, Lin Zheng, Ke Wei, Chunfeng Pan, Zhifei Ma, Yang Xia and Aiping Zhang
    Citation: Cancer Cell International 2022 22:31
  20. Raw areca nut (RAN) consumption induces oral, esophageal and gastric cancers, which are significantly associated with the overexpression of pituitary tumor transforming gene 1/securin and chromosomal instabili...

    Authors: Nabamita Boruah, Chongtham Sovachandra Singh, Pooja Swargiary, Hughbert Dkhar and Anupam Chatterjee
    Citation: Cancer Cell International 2022 22:30
  21. Liver is the most common metastatic site of colorectal cancer (CRC) and liver metastasis (LM) determines subsequent treatment as well as prognosis of patients, especially in T1 patients. T1 CRC patients with L...

    Authors: Tenghui Han, Jun Zhu, Xiaoping Chen, Rujie Chen, Yu Jiang, Shuai Wang, Dong Xu, Gang Shen, Jianyong Zheng and Chunsheng Xu
    Citation: Cancer Cell International 2022 22:28
  22. Circular RNAs (circRNAs) have emerged as vital regulators of the initiation and progression of diverse kinds of human cancers. In this study, we explored the role of hsa_circ_0000231 and its downstream pathway in...

    Authors: Wei Zhang, Bo Wang, Yilin Lin, Yang Yang, Zhen Zhang, Quan Wang, Haoran Zhang, Kewei Jiang, Yingjiang Ye, Shan Wang and Zhanlong Shen
    Citation: Cancer Cell International 2022 22:27
  23. Long noncoding RNAs (lncRNAs) play a critical role in innate and adaptive immune responses. Thus, we aimed to identify ideal subtypes for head and neck squamous cell carcinoma (HNSCC) based on immune-related l...

    Authors: Ruoyan Cao, Lin Cui, Jiayu Zhang, Xianyue Ren, Bin Cheng and Juan Xia
    Citation: Cancer Cell International 2022 22:25
  24. The Src homology and collagen 4 (SHC4) is an important intracellular adaptor protein that has been shown to play a pro-cancer role in melanoma and glioma. However, the biological function and detailed mechanis...

    Authors: Xin Zhang, Hongwei Zhang, Zhibin Liao, Jiacheng Zhang, Huifang Liang, Weixing Wang, Jia Yu and Keshuai Dong
    Citation: Cancer Cell International 2022 22:24
  25. Krüppel‐like factors (KLFs) are zinc finger proteins which participate in transcriptional gene regulation. Although increasing evidence indicate that KLFs are involved in carcinogenesis and progression, its cl...

    Authors: Ke-Yun Zhu, Yao Tian, Ying-Xi Li, Qing-Xiang Meng, Jie Ge, Xu-Chen Cao, Ti Zhang and Yue Yu
    Citation: Cancer Cell International 2022 22:23
  26. In recent years, the Fibrinogen to pre-albumin ratio (FPR) has been reported in many studies to be significantly associated with the prognosis of various cancers. This systematic review and meta-analysis aimed...

    Authors: Baibei Li, Huachu Deng, Ziyan Zhou and Bo Tang
    Citation: Cancer Cell International 2022 22:22
  27. Molecular markers play an important role in predicting clinical outcomes in pancreatic adenocarcinoma (PAAD) patients. Analysis of the ferroptosis-related genes may provide novel potential targets for the prog...

    Authors: Jihua Yang, XiaoHong Wei, Fang Hu, Wei Dong and Liao Sun
    Citation: Cancer Cell International 2022 22:21
  28. The roles of Polypyrimidine tract-binding protein 3 (PTBP3) in regulating lung squamous cell carcinoma (LUSC) cells progression is unclear. The aim of this study was to investigate the role of PTBP3 in LUSC.

    Authors: Yingji Chen, Ying Ji, Suo Liu, Yicai Liu, Wei Feng and Longyu Jin
    Citation: Cancer Cell International 2022 22:19
  29. Short-term starvation (STS) has gradually been confirmed as a treatment method that synergistically enhances the effect of chemotherapy on malignant tumours. In clinical applications, there are still some limi...

    Authors: Wang Zhi, Suting Li, Yuting Wan, Fuwen Wu and Li Hong
    Citation: Cancer Cell International 2022 22:18

    The Correction to this article has been published in Cancer Cell International 2022 22:131

  30. HPV as the main cause of cervical cancer has long been revealed, but the detailed mechanism has not yet been elucidated. The role of testis/cancer antigen in cervical cancer has been revealed. However, there a...

    Authors: Yuanhang Zhu, Chenchen Ren, Li Yang, Zhenan Zhang, Meiyuan Gong and Kebing Chen
    Citation: Cancer Cell International 2022 22:17

    The Correction to this article has been published in Cancer Cell International 2022 22:77

  31. Nasopharyngeal carcinoma (NPC) is a deadly cancer, mainly presenting in southeast and east Asia. Long noncoding RNAs (lncRNAs) play essential roles in cancer progression. Exosomes are critical for intercellula...

    Authors: Hongchao Yao, Linli Tian, Bingrui Yan, Like Yang and Yushan Li
    Citation: Cancer Cell International 2022 22:16
  32. Accumulating evidence has revealed that aberrant microRNA (miRNA) expression can affect the development of chemotherapy drug resistance by modulating the expression of relevant target proteins. Emerging eviden...

    Authors: Yang Zhou, Chunyan Wang, Jinye Ding, Yingying Chen, Yaoqi Sun and Zhongping Cheng
    Citation: Cancer Cell International 2022 22:15
  33. Mucin-1 (MUC-1) is a transmembrane glycoprotein, which bears many similarities between dogs and humans. Since the existence of animal models is essential to understand the significant factors involved in breas...

    Authors: Rana Vafaei, Mitra Samadi, Aysooda Hosseinzadeh, Khadijeh Barzaman, MohammadReza Esmailinejad, Zohreh Khaki and Leila Farahmand
    Citation: Cancer Cell International 2022 22:14
  34. N6-methyladenosine (m6A) is a dynamic and reversible internal RNA structure of eukaryotic mRNA. YTH domain family 2 (YTHDF2), an m6A-specific reader YTH domain family, plays fundamental roles in several types ...

    Authors: Peng Xu, Kang Hu, Ping Zhang, Zhi-Gang Sun and Nan Zhang
    Citation: Cancer Cell International 2022 22:13
  35. At present, more than one cell death pathways have been found, one of which is ferroptosis. Ferroptosis was discovered in 2012 and described as an iron-dependent and lipid peroxidation-driven regulated cell de...

    Authors: Qing Nie, Yue Hu, Xiao Yu, Xiao Li and Xuedong Fang
    Citation: Cancer Cell International 2022 22:12
  36. N6-methyladenosine (m6A) has emerged as a significant regulator of the progress of various cancers. However, its role in lung adenocarcinoma (LUAD) remains unclear. Here, we explored the biological function and u...

    Authors: Yiming Xu, Dandan Lv, Chao Yan, Hua Su, Xue Zhang, Yangfeng Shi and Kejing Ying
    Citation: Cancer Cell International 2022 22:11
  37. Chronic myeloid leukemia (CML) and acute myeloid leukemia (AML) are two common malignant disorders in leukemia. Although potent drugs are emerging, CML and AML may still relapse after the drug treatment is sto...

    Authors: Li-Rong Yang, Zhu-Ying Lin, Qing-Gang Hao, Tian-Tian Li, Yun Zhu, Zhao-Wei Teng and Jun Zhang
    Citation: Cancer Cell International 2022 22:10
  38. Glioblastoma multiforme (GBM) is a heterogeneous CNS neoplasm which causes significant morbidity and mortality. One reason for the poor prognostic outcome of GBM is attributed to the presence of cancer stem ce...

    Authors: Hany E. Marei, Asmaa Althani, Nahla Afifi, Anwarul Hasan, Thomas Caceci, Armando Felsani, Giuseppe Tringali, Ingrid Cifola, Giacomo Pozzoli and Carlo Cenciarelli
    Citation: Cancer Cell International 2022 22:9
  39. In humans, riboflavin must be obtained through intestinal absorption because it cannot be synthesized by the body. SLC52A2 encodes a membrane protein belonging to the riboflavin transporter protein family and ...

    Authors: Lilong Zhang, Man Li, Zhoujun Cui, Dongqi Chai, Yongjun Guan, Chen Chen and Weixing Wang
    Citation: Cancer Cell International 2022 22:8
  40. Bladder cancer (BLCA) is one of the most common malignancies worldwide. One of the main reasons for the unsatisfactory management of BLCA is the complex molecular biological mechanism. Annexin A1 (ANXA1), a Ca2+-...

    Authors: Piao Li, Lingling Li, Zhou Li, Shennan Wang, Ruichao Li, Weiheng Zhao, Yanqi Feng, Shanshan Huang, Lu Li, Hong Qiu and Shu Xia
    Citation: Cancer Cell International 2022 22:7
  41. Ovarian cancer is the most aggressive gynecological malignancy. Transcriptional regulators impact the tumor phenotype and, consequently, clinical progression and response to therapy. PHD finger protein 20-like...

    Authors: Dulce Rosario Alberto-Aguilar, Verónica Ivonne Hernández-Ramírez, Juan Carlos Osorio-Trujillo, Dolores Gallardo-Rincón, Alfredo Toledo-Leyva and Patricia Talamás-Rohana
    Citation: Cancer Cell International 2022 22:6
  42. Alternative splicing (AS) plays important roles in transcriptome and proteome diversity. Its dysregulation has a close affiliation with oncogenic processes. This study aimed to evaluate AS-based biomarkers by ...

    Authors: Boxue He, Cong Wei, Qidong Cai, Pengfei Zhang, Shuai Shi, Xiong Peng, Zhenyu Zhao, Wei Yin, Guangxu Tu, Weilin Peng, Yongguang Tao and Xiang Wang
    Citation: Cancer Cell International 2022 22:5
  43. Serine/threonine protein kinase 25 (STK25) plays an important role in regulating glucose and insulin homeostasis and in ectopic lipid accumulation. It directly affects the progression and prognosis of nonalcoh...

    Authors: Yichao Zhang, Junhui Xu, Zhendong Qiu, Yongjun Guan, XiaoYi Zhang, Xin Zhang, Dongqi Chai, Chen Chen, Qinyong Hu and Weixing Wang
    Citation: Cancer Cell International 2022 22:4

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