Skip to main content

Articles

Page 6 of 41

  1. ZKSCAN3, a zinc-finger transcription factor containing KRAB and SCAN domains, has been reported to be regulated in several human cancers. However, its expression and function in hepatocellular carcinoma (HCC) ...

    Authors: Jieqiong Li, Nan Hao, Juan Han, Mi Zhang, Xiaomei Li and Nan Yang

    Citation: Cancer Cell International 2020 20:216

    Content type: Primary research

    Published on:

  2. One of the most prominent features of tumor cells is uncontrolled cell proliferation caused by an abnormal cell cycle, and the abnormal expression of cell cycle-related proteins gives tumor cells their invasiv...

    Authors: Kai Liu, Minying Zheng, Rui Lu, Jiaxing Du, Qi Zhao, Zugui Li, Yuwei Li and Shiwu Zhang

    Citation: Cancer Cell International 2020 20:213

    Content type: Review

    Published on:

  3. Dietary fiber is effective for colorectal cancer (CRC) treatment. Interleukin-6 (IL-6) and its adaptors are potential targets for CRC therapy. Butyrate, a metabolite of dietary fiber, is a new, highly safe typ...

    Authors: Yin Yuan, Bo Li, Yanbin Kuang, Shuo Ni, Aoxiang Zhuge, Jing Yang, Longxian Lv, Silan Gu, Ren Yan, Yating Li, Kaicen Wang, Liya Yang, Xueling Zhu, Jingjing Wu, Xiaoyuan Bian and Lanjuan Li

    Citation: Cancer Cell International 2020 20:212

    Content type: Primary research

    Published on:

  4. Circular RNAs (circRNAs) are small non-coding RNAs with a unique ring structure and play important roles as gene regulators. Disturbed expressions of circRNAs is closely related to varieties of pathological pr...

    Authors: Huixin Song, Qiaofei Liu and Quan Liao

    Citation: Cancer Cell International 2020 20:211

    Content type: Review

    Published on:

  5. Hydroxysteroid 17-Beta Dehydrogenase 6 (HSD17B6), a key protein involved in synthetizing dihydrotestosterone, is abundant in the liver. Previous studies have suggested a role for dihydrotestosterone in modulat...

    Authors: Lei Lv, Yujia Zhao, Qinqin Wei, Ye Zhao and Qiyi Yi

    Citation: Cancer Cell International 2020 20:210

    Content type: Primary research

    Published on:

  6. GSK-J4 is the inhibitor of H3K27me3 demethylase. Recent studies demonstrated that GSK-J4 could affect the proliferation and apoptosis of a variety of cancer cells. However, the effects and underlying mechanism...

    Authors: Xuan Chu, Liang Zhong, Lihua Yu, Ling Xiong, Jian Li, Wenran Dan, Jiao Ye, Chen Liu, Xu Luo and Beizhong Liu

    Citation: Cancer Cell International 2020 20:209

    Content type: Primary research

    Published on:

  7. Lung cancer is the most common cancer worldwide, and metastasis is the leading cause of lung cancer related death. However, the molecular network involved in lung cancer metastasis remains incompletely describ...

    Authors: Qing Cao, Zewen Dong, Shuzhen Liu, Guoyan An, Bianbian Yan and Lei Lei

    Citation: Cancer Cell International 2020 20:208

    Content type: Primary research

    Published on:

  8. The pathogenesis and developmental mechanism of early-stage (FIGO 2009 IA2-IIA2) cervical cancer (CC) remain unclear. Seeking novel molecular biomarkers based on The Cancer Genome Atlas (TCGA) will facilitate ...

    Authors: Shuhang Qin, Yuandong Liao, Qiqiao Du, Wei Wang, Jiaming Huang, Pan Liu, Chunliang Shang, Tianyu Liu, Meng Xia and Shuzhong Yao

    Citation: Cancer Cell International 2020 20:206

    Content type: Primary research

    Published on:

  9. Inflammation is one of a main reason for colon cancer progression and poor prognosis. The high-mobility group box-1 (HMGB1) and glutathione peroxidase 4 (GPX4) are responsible for inflammation, but the relatio...

    Authors: Yuhan Yang, Ling Yang, Sheng Jiang, Ting Yang, Jingbin Lan, Yun Lei, Hao Tan and Kejian Pan

    Citation: Cancer Cell International 2020 20:205

    Content type: Primary research

    Published on:

  10. Papillary thyroid cancer (PTC) is a type of malignant tumor with excellent prognosis, accounting for more than 80% of thyroid cancer. Recently, numerous studies illustrated the importance of N6-methyladenosine (m

    Authors: Xinyi Wang, Xiaorui Fu, Junjia Zhang, Chengfeng Xiong, Shuyong Zhang and Yunxia Lv

    Citation: Cancer Cell International 2020 20:203

    Content type: Primary research

    Published on:

  11. Circ-centro-some/spindle pole-associated protein (CSPP1) has been confirmed to be characterized in diverse human malignancies and its ectopic expression may regulate tumor progression and development. However,...

    Authors: Qian Sun, Rui Yu, Chunfeng Wang, Jianning Yao and Lianfeng Zhang

    Citation: Cancer Cell International 2020 20:202

    Content type: Primary research

    Published on:

    The Correction to this article has been published in Cancer Cell International 2020 20:293

  12. Long non-coding RNA H19 (lncRNA H19) has been implicated in tumorigenesis and metastasis of breast cancer through regulating epithelial to mesenchymal transition (EMT); however, the underlying mechanisms remai...

    Authors: Yang Li, Hong-Yu Ma, Xiao-Wei Hu, Yuan-Yuan Qu, Xin Wen, Yu Zhang and Qing-Yong Xu

    Citation: Cancer Cell International 2020 20:200

    Content type: Primary research

    Published on:

  13. Esophageal cancer is the sixth leading cause of cancer-related mortality worldwide, which is partially due to limited progress of therapy. Apatinib, an inhibitor of VEGFR2, has a promising antitumor effect on ...

    Authors: Bin Wei, Yuanyuan Wang, Jiawei Wang, Xiaomin Cai, Lingyan Xu, Jingjing Wu, Ying Wang, Wen Liu, Yanhong Gu, Wenjie Guo and Qiang Xu

    Citation: Cancer Cell International 2020 20:198

    Content type: Primary research

    Published on:

  14. Radiotherapy, chemotherapy, and surgery have made crucial strides in glioblastoma treatment, yet they often fail; thus, new treatment and new detection methods are needed. Aberrant expression of Nanos3 has bee...

    Authors: Fengyu Zhang, Ruilai Liu, Cheng Liu, Haishi Zhang and Yuan Lu

    Citation: Cancer Cell International 2020 20:197

    Content type: Primary research

    Published on:

  15. Forkhead box C2 (FOXC2) is a crucial factor involving in various cancers. However, its functions in hepatocellular carcinoma (HCC) is unknown. Here, we explored the role of FOXC2 in the progression of HCC and ...

    Authors: Jinzhang Chen, Xiaoxiang Rong, Xinhui Liu, Dayong Zheng, Xiaodong Rong, Fengsheng Chen, Peng Zhao, Feiye Liu and Jian Ruan

    Citation: Cancer Cell International 2020 20:196

    Content type: Primary research

    Published on:

  16. Skin cutaneous melanoma (SKCM) is one of the most malignant and aggressive cancers, causing about 72% of deaths in skin carcinoma. Although extensive study has explored the mechanism of recurrence and metastas...

    Authors: Biao Huang, Wei Han, Zu-Feng Sheng and Guo-Liang Shen

    Citation: Cancer Cell International 2020 20:195

    Content type: Primary research

    Published on:

  17. Lung cancer is the most common malignant tumor in the world. The Whole-proteome microarray showed that ubiquitin ligase chromatin assembly factor 1 subunit B (CHAF1B) expression in A549/DDP cells is higher tha...

    Authors: Lian Gong, Yi Hu, Dong He, Yuxing Zhu, Liang Xiang, Mengqing Xiao, Ying Bao, Xiaoming Liu, Qinghai Zeng, Jianye Liu, Ming Zhou, Yanhong Zhou, Yaxin Cheng, Yeyu Zhang, Liping Deng, Rongrong Zhu…

    Citation: Cancer Cell International 2020 20:194

    Content type: Primary research

    Published on:

  18. Gastric cancer (GC) remains one of the most common digestive malignancies worldwide and ranked third causes of cancer-related death. Mounting evidence has revealed that miRNAs exert critical regulatory roles i...

    Authors: Yingfeng Wei, Sheng Guo, Jianhua Tang, Jianjun Wen, Huifen Wang, Xiaobo Hu and Qiuping Gu

    Citation: Cancer Cell International 2020 20:193

    Content type: Primary research

    Published on:

  19. Rhabdomyosarcoma (RMS) is the most common pediatric soft tissue sarcoma. There are two subtypes, fusion gene-positive RMS (FP-RMS) and fusion gene-negative RMS (FN-RMS), depending on the presence of a fusion g...

    Authors: Kazutaka Ouchi, Mitsuru Miyachi, Shigeki Yagyu, Ken Kikuchi, Yasumichi Kuwahara, Kunihiko Tsuchiya, Tomoko Iehara and Hajime Hosoi

    Citation: Cancer Cell International 2020 20:192

    Content type: Primary research

    Published on:

  20. Nicotinamide N-methyltransferase (NNMT) is highly expressed in several cancers and can regulate cell epigenetic status and various cell metabolism pathways, such as ATP synthesis and cellular stress response. ...

    Authors: Haitao Yu, Xi Zhou, Yanzhong Wang, Xucheng Huang, Jun Yang, Jin Zeng, Guoli Li, Xinyou Xie and Jun Zhang

    Citation: Cancer Cell International 2020 20:191

    Content type: Primary research

    Published on:

  21. Cisplatin (DDP) is a major chemotherapeutic drug which was widely used for cervical cancer (CC) patients with advanced or recurrent although its limitation in the development of resistance. LncRNA nicotinamide...

    Authors: Yanjie Liu, Ruixia Guo, Yuhuan Qiao, Liping Han and Mingzhu Liu

    Citation: Cancer Cell International 2020 20:190

    Content type: Primary research

    Published on:

  22. The stem cell factor SALL4 is reactivated in human cancers. SALL4 plays diverse roles in tumor growth, metastasis, and drug resistance, but its role in tumor metabolism has not been well characterized.

    Authors: Meng Shao, Jiayin Zhang, Jiahui Zhang, Hui Shi, Yu Zhang, Runbi Ji, Fei Mao, Hui Qian, Wenrong Xu and Xu Zhang

    Citation: Cancer Cell International 2020 20:188

    Content type: Primary research

    Published on:

  23. Exosomes (EXs) are small extracellular vesicles, a size range of 40-100 nm in diameter, actively secreted by most eukaryotic cells into surrounding body fluids like blood, saliva, urine, bile, breast milk and ...

    Authors: Leyla Norouzi-Barough, Amir Asgari Khosro Shahi, Farnoosh Mohebzadeh, Ladan Masoumi, Mohammad Reza Haddadi and Sadegh Shirian

    Citation: Cancer Cell International 2020 20:187

    Content type: Review

    Published on:

  24. Programmed death-ligand 1 (PD-L1) expression determines the eligibility for anti-PD-1 treatment in patients with advanced gastric cancer, but evidence indicates that PD-L1 staining is heterogeneous. Patients w...

    Authors: Min Ye, Dan Huang, Qiongyan Zhang, Weiwei Weng, Cong Tan, Guangqi Qin, Wenhua Jiang, Weiqi Sheng and Lei Wang

    Citation: Cancer Cell International 2020 20:186

    Content type: Primary research

    Published on:

  25. Our previous clinical study has shown that Chinese herbal medicine (CHM) Fuzheng Kang-Ai (FZKA) decoction is effective in treating advanced lung cancer patients through prolonging the drug resistance to Gefiti...

    Authors: Sumei Wang, Zhiwei Peng, Wenjuan Li, Shunqin Long, Shujing Xiao and Wanyin Wu

    Citation: Cancer Cell International 2020 20:185

    Content type: Primary research

    Published on:

  26. Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent malignancies and a major cause of cancer related death worldwide, especially in China. Cell lines are widely used disease models for basic...

    Authors: Xiang Li, Dongping Tian, Yi Guo, Shiyue Qiu, Zexin Xu, Wen Deng and Min Su

    Citation: Cancer Cell International 2020 20:184

    Content type: Primary research

    Published on:

  27. Endometrial cancer is the fourth most common cancer in women. The death rate for endometrial cancer has increased. Glycolysis of cellular respiration is a complex reaction and is the first step in most carbohy...

    Authors: JinHui Liu, SiYue Li, Gao Feng, HuangYang Meng, SiPei Nie, Rui Sun, Jing Yang and WenJun Cheng

    Citation: Cancer Cell International 2020 20:183

    Content type: Primary research

    Published on:

  28. Ovarian cancer (OC) is a common female reproductive malignancy with a high mortality rate. Although LAMA4 was observed to be downregulated in OC cells, its mechanism in regulating OC metastasis is still unknow...

    Authors: Yang Liu, Yangchun Xu, Lei Ding, Lili Yu, Butian Zhang and Dan Wei

    Citation: Cancer Cell International 2020 20:181

    Content type: Primary research

    Published on:

  29. MicroRNA 942-5p (miR-942-5p) has been reported to promote migration and invasion in non-small cell lung cancer (NSCLC), but the underlying mechanism is not completely understood. The interplay between long non...

    Authors: Qun Wang, Jing Wu, Hui Huang, Yan Jiang, Ying Huang, Hongyan Fang, Gang Zheng, Xiaochun Zhou, Yujuan Wu, Changjiang Lei and Desheng Hu

    Citation: Cancer Cell International 2020 20:180

    Content type: Primary research

    Published on:

  30. Obesity confers increased risk for various types of cancer. PD-L1 is a key molecule in tumor immune evasion by inducing T cell exhaustion. The relationship between obesity and PD-L1 is still ambiguous. This st...

    Authors: Zhi Li, Cai Zhang, Jing-Xia Du, Jia Zhao, Meng-Ting Shi, Man-Wen Jin and Hui Liu

    Citation: Cancer Cell International 2020 20:179

    Content type: Primary research

    Published on:

  31. The purpose of this study is to perform bioinformatics analysis of autophagy-related genes in gastric cancer, and to construct a multi-gene joint signature for predicting the prognosis of gastric cancer.

    Authors: Jieping Qiu, Mengyu Sun, Yaoqun Wang and Bo Chen

    Citation: Cancer Cell International 2020 20:178

    Content type: Primary research

    Published on:

  32. Bladder cancer is one of the most prevalent malignancies worldwide. However, traditional indicators have limited predictive effects on the clinical outcomes of bladder cancer. The aim of this study was to deve...

    Authors: Chen Zhang, Xin Gou, Weiyang He, Huaan Yang and Hubin Yin

    Citation: Cancer Cell International 2020 20:177

    Content type: Primary research

    Published on:

  33. Cutaneous melanoma is one of the most aggressive and lethal skin cancers. It is greatly important to identify prognostic biomarkers to guide the clinical management. However, it is technically challenging for ...

    Authors: Lu Zhang, Qiang Wang, Lijie Wang, Longxiang Xie, Yang An, Guosen Zhang, Wan Zhu, Yongqiang Li, Zhihui Liu, Xiaochen Zhang, Panpan Tang, Xiaozheng Huo and Xiangqian Guo

    Citation: Cancer Cell International 2020 20:176

    Content type: Primary research

    Published on:

  34. Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer that lacks expression of estrogen receptor (ER) and progesterone receptor (PR) and the human epidermal growth factor recepto...

    Authors: Ruishan Zhang, Xiang Li, Zhuangkai Liu, Yuying Wang, Hao Zhang and Hong Xu

    Citation: Cancer Cell International 2020 20:175

    Content type: Primary research

    Published on:

  35. Ovarian cancer is the third most common gynecological cancer in the world but the leading cause of death among gynecological malignancies. Epithelial splicing regulatory protein-1 (ESRP1), a key negative splic...

    Authors: Guanming Deng, Xiaofang Zhou, Le Chen, Ying Yao, Junjun Li, Yun Zhang, Chenhui Luo, Lijuan Sun and Jie Tang

    Citation: Cancer Cell International 2020 20:174

    Content type: Primary research

    Published on:

  36. Circular RNAs, as hopeful diagnosis markers and therapeutic molecules, have been studied, probed and applied into several diseases, such as cardiovascular diseases, systemic lupus erythematosus, leukemia, pulm...

    Authors: Zhuo-Zheng Liang, Cheng Guo, Man-Man Zou, Ping Meng and Tian-Tuo Zhang

    Citation: Cancer Cell International 2020 20:173

    Content type: Review

    Published on:

  37. Human polypyrimidine tract binding protein 3 (PTBP3), which belongs to the PTB family, demonstrate a significant tumorigenic capability in a variety of malignancies. However, the correlation between PTBP3 expr...

    Authors: Qiong Wu, Bo Zhang, Ben Li, Xiang Cao, Xinming Chen and Qun Xue

    Citation: Cancer Cell International 2020 20:172

    Content type: Primary research

    Published on:

  38. Circular RNAs (circRNAs) are a special kind of non-coding RNAs that are implicated in cancer malignant behavior, including glycolysis. However, their contributions to gastric cancer (GC) cell glycolysis are st...

    Authors: Jia Liu, Haiying Liu, Qingshan Zeng, Pei Xu, Mingxing Liu and Ning Yang

    Citation: Cancer Cell International 2020 20:171

    Content type: Primary research

    Published on:

  39. Drug resistance and chemotherapy-induced peripheral neuropathy continue to be significant problems in the successful treatment of acute lymphoblastic leukemia (ALL). 5,7-Dibromo-N-alkylisatins, a class of potent ...

    Authors: Bryce Keenan, Rocio K. Finol-Urdaneta, Ashleigh Hope, John B. Bremner, Maria Kavallaris, Daniel Lucena-Agell, María Ángela Oliva, Jose Fernando Díaz and Kara L. Vine

    Citation: Cancer Cell International 2020 20:170

    Content type: Primary research

    Published on:

  40. Nestin has been revealed to promote tumorigenesis, progression, metastasis, and angiogenesis of breast cancer. Although the prognostic and clinicopathological impact of nestin expression on breast cancer patie...

    Authors: Xinyi Zhang, Changsheng Xing, Wenting Guan, Lang Chen, Kai Guo, Anze Yu and Kai Xie

    Citation: Cancer Cell International 2020 20:169

    Content type: Primary research

    Published on:

  41. Renal cell carcinoma (RCC) is one of the most common aggressive malignant tumors in urogenital system, and the clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal carcinoma. Immune rela...

    Authors: Yuanbin Jiang, Xin Gou, Zongjie Wei, Jianyu Tan, Haitao Yu, Xiang Zhou and Xinyuan Li

    Citation: Cancer Cell International 2020 20:166

    Content type: Primary research

    Published on:

  42. The objective of the present study is to comprehensively evaluate the impact of the rs1800975 A/G polymorphism within the human xeroderma pigmentosum group A (XPA) gene on susceptibility to overall cancer by perf...

    Authors: Maoxi Yuan, Chunmei Yu and Kuiying Yu

    Citation: Cancer Cell International 2020 20:164

    Content type: Primary research

    Published on:

Annual Journal Metrics

Institutional membership

Visit the membership page to check if your institution is a member and learn how you could save on article-processing charges (APCs).

Funding your APC

​​​​​​​Open access funding and policy support by SpringerOpen​​

​​​​We offer a free open access support service to make it easier for you to discover and apply for article-processing charge (APC) funding. Learn more here